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Timing May Be Everything When Taking Meds

Using new bioinformatics tools to analyze thousands of human tissue samples, researchers created a new database of daily rhythms in human gene activity—including many genes that regulate how drugs work. Reporting in Science Translational Medicine,...
10-Sep-2018 2:00 PM EDT Add to Favorites

Scientists Block RNA Silencing Protein in Liver to Prevent Obesity and Diabetes in Mice

Obesity and its related ailments like type 2 diabetes and fatty liver disease pose a major global health burden, but researchers report in Nature Communications that blocking an RNA-silencing protein in the livers of mice keeps the animals from...
10-Sep-2018 11:45 AM EDT Add to Favorites


Scientists Close in on Mystery Surrounding Dangerous Blood Syndromes

Scientists may be on the road to solving the mystery of a group of mostly incurable blood diseases called myelodysplastic syndromes (MDS), which cause people to have immature, malfunctioning bone marrow cells that fuel a diverse set of health...
23-Aug-2018 12:30 AM EDT Add to Favorites


Taking a Pill Can Effectively Treat Brutal Lung Disease

Researchers report in Nature Communications they figured out why air sacs in the lungs clog up with a thick substance called surfactant in a brutal disease called Pulmonary Alveolar Proteinosis (PAP), and they show taking cholesterol-busting pills...
7-Aug-2018 1:45 PM EDT Add to Favorites


Scientists Learn More about How Gene Linked to Autism Affects Brain

New preclinical research shows a gene already linked to a subset of people with autism spectrum disorder is critical to healthy neuronal connections in the developing brain, and its loss can harm those connections to help fuel the complex...
13-Jun-2018 2:45 PM EDT Add to Favorites


Study Suggests Well-Known Growth Suppressor Actually Fuels Lethal Brain Cancers

Scientists report finding a potentially promising treatment target for aggressive and deadly high-grade brain cancers like glioblastoma. Publishing online June 18 in Nature Cell Biology, the study also reports the current lack of a drug that hits...
14-Jun-2018 11:05 AM EDT Add to Favorites

Helping Preterm Infants Grow Bigger Kidneys Would Prevent Kidney Disease Later in Life

A study led by scientists at Cincinnati Children’s reveals one mechanism involved in regulating when nephron formation ends. If translated to clinical practice years from now, the result could be reduced need for kidney transplants and fewer...
21-May-2018 3:00 PM EDT Add to Favorites


Taming Random Gene Changes As Our Bodies Start to Form

Scientists exploring how to tame random gene fluctuations as the embryos that become our bodies start to form have identified a control switch in the vertebrate segmentation clock of developing zebrafish. The researchers report in Cell Reports their...
10-May-2018 8:30 AM EDT Add to Favorites

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