Researchers Find Cause of Rare, Fatal Disease That Turns Babies’ Lips and Skin Blue

Scientists used a gene editing method called CRISPR/Cas9 to generate mice that mimic a respiratory disorder in newborn infants that turns their lips and skin blue. The new laboratory model allowed researchers to find the ailment’s cause and a...
19-Jun-2019 9:00 AM EDT Add to Favorites

3 Signs of Progress Against Sickle Cell Disease

June 19 is World Sickle Cell Awareness Day. Scientists at Cincinnati Children's have recently made three important steps forward in helping people with sickle cell in the U.S. and in sub-Saharan Africa live longer, better lives.
19-Jun-2019 8:05 AM EDT Add to Favorites

Scientists Identify Genes Associated with Biliary Atresia Survival

Scientists at Cincinnati Children’s Hospital Medical Center have identified an expression pattern of 14 genes at the time of diagnosis that predicts two year, transplant-free survival in children with biliary atresia – the most common diagnosis...
17-Jun-2019 4:00 PM EDT Add to Favorites

Scientists Bioengineer Human Liver Disease in the Lab to Find New Treatments

Scientists successfully bioengineered human liver organoids that faithfully mimic key features of fatal liver disease in the laboratory. This allowed them to uncover underlying disease biology in the organoids and test a potential therapy that in...
23-May-2019 11:00 AM EDT Add to Favorites

Potential New Target Emerges for Preventing Preterm Birth

Experts at Cincinnati Children’s report that the systemic inflammatory process that triggers preterm birth begins in an unexpected location that suggests new ways to develop preventative medications.
2-May-2019 9:00 AM EDT Add to Favorites

Major Grant Fuels Hunt for Universal Flu Vaccine

Funds from the National Institutes of Health will accelerate the chase for one of medicine’s most elusive goals: a universal influenza vaccine.
2-May-2019 2:05 PM EDT Add to Favorites

Shining Light on Rare Nerve Tumors Illuminates a Fresh Path for Fighting Cancer

Experts use emerging technique to reveal that a protein named “Merlin” may interact with 50 other proteins to trigger the rare condition neurofibromatosis 2 (NF2). But this discovery has implications that go far beyond NF2 itself.
22-Apr-2019 11:05 AM EDT Add to Favorites

Overlooked Molecular Machine in Cell Nucleus May Hold Key to Treating Aggressive Leukemia

Many people fighting a very aggressive form of acute myeloid leukemia (AML) don’t survive more than five years. These very sick patients are often unable to receive the only cure—a bone marrow transplant. Now, an international team of scientists...
18-Apr-2019 11:05 AM EDT Add to Favorites

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