Cellular culprit suspected of pushing dengue fever from bad to worse is cleared by advanced transcriptomics

No one knows what makes a mild dengue viral infection morph into a severe and sometimes deadly dengue hemorrhagic fever/dengue shock syndrome. Experts previously believed the likely cause was ramped up activity of T cells, which can massively boost...
19-Dec-2019 3:05 PM EST Add to Favorites

La Jolla Institute for Immunology acquires Berkeley Lights Beacon® platform

La Jolla Institute for Immunology (LJI) is placing their confidence in Berkeley Lights’ Beacon® Optofluidic Platform and B cell antibody discovery workflow to accelerate the discovery of rare and lifesaving antibodies for the treatment of...
9-Dec-2019 1:00 AM EST Add to Favorites

LJI researchers reveal unexpected versatility of an ancient DNA repair factor

New work from the lab of La Jolla Institute for Immunology (LJI) investigator Anjana Rao, Ph.D., reveals a previously unrecognized activity for a highly conserved DNA repair factor. The study reports that mouse lymphocytes engineered to lack that...
26-Nov-2019 4:35 PM EST Add to Favorites

Seqster Signs 3-year License Agreement of SRP™ to La Jolla Institute of Immunology for Asthma Study

Seqster, the award-winning SaaS-based technology platform enabling consumer-centered health data management, today announced a 3-year licensing deal and partnership with La Jolla Institute of Immunology (LJI) to support the execution of a $6.9...
22-Oct-2019 11:30 AM EDT Add to Favorites

Lassa Virus’ Soft Spot Revealed

A new study, led by researchers at La Jolla Institute for Immunology (LJI), identified and then reverse engineered the molecular properties shared by antibodies that are particularly efficient at inactivating or “neutralizing” Lassa virus...
5-Aug-2019 8:05 AM EDT Add to Favorites

TET proteins: double agents in DNA methylation prevent catastrophic cancer

In their latest study, published in this week’s online issue of Proceedings of the National Academy of Sciences, researchers at La Jolla Institute for Immunology (LJI), reveal how the finely tuned balance between DNA methylation and demethylation...
24-Jul-2019 2:45 PM EDT Add to Favorites

No cell is an island

In a new study, published on June 25, 2019, in the journal eLife, the researchers report that higher levels of doublets can be found in people with severe cases of tuberculosis or dengue fever.
24-Jun-2019 5:05 PM EDT Add to Favorites

To kill tumors, activate this elite group of T cells

Tissue-resident memory T cells (TRMs) are known to help the body fight infection, but they are also key tumor fighters. A new study reveals that these cells are unique in their ability to seek out and kill tumor cells without suffering from the...
21-Jun-2019 5:05 PM EDT Add to Favorites

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