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DICE: Immune cell atlas goes live

For more than four years, a team of LJI scientists led by Associate Professor Pandurangan Vijayanand, M.D., Ph.D., has been undertaking a massive immunoprofiling effort, detailing how variations in DNA sequence impact gene activity in different...
12-Nov-2018 12:05 PM EST Add to Favorites

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Maternally-Acquired Zika Immunity Can Increase Dengue Disease Severity in Mouse Pups

In this study, La Jolla Institute for Immunology (LJI) investigator Sujan Shresta, Ph.D., who studies both dengue and Zika viruses, explored awhether maternal immunity to Zika virus, which is structurally and genetically similar to dengue, might...
8-Nov-2018 5:05 PM EST Add to Favorites

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Global immunoprofiling effort reveals multifunctional T cell response during Zika infection

The latest study by researchers at the La Jolla Institute for Immunology (LJI) and their collaborators provide the first in-depth characterization of the body’s cytotoxic T cell response to Zika, which plays an important role in providing...
13-Nov-2018 11:05 AM EST Add to Favorites

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LJI investigators discover how protein pair controls cellular calcium signals

Two studies recently published by La Jolla Institute for Immunology (LJI) investigators Patrick Hogan, PhD, and Aparna Gudlur, PhD, report how a calcium-sensing protein called STIM1 signals that it's time to initiate calcium retrieval and then...
26-Oct-2018 1:35 PM EDT Add to Favorites

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La Jolla Institute Receives $ 4.5 Mill Cancer Moonshot Award

Researchers at La Jolla Institute for Immunology (LJI) and UC San Diego have been awarded $ 4.5 million as part of the National Cancer Institute’s Cancer Moonshot initiative. The funding will support research to develop new and improved...
18-Oct-2018 1:05 PM EDT Add to Favorites

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Researchers Find Elusive Source of Most Abundant Immune Cell

Neutrophils—short-lived, highly mobile and versatile—outnumber all other immune cells circulating through the blood stream. Now, researchers at La Jolla Institute for Allergy and Immunology identified a progenitor of neutrophils in the bone...
24-Aug-2018 11:35 AM EDT Add to Favorites

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Innate Lymphoid Cells (ILCs) form an essential line of defense against enteric bacteria

Mice deficient in innate lymphoid cells are vulnerable to lethal infection by the bacterial pathogen Yersinia enterocolitica (YE), which causes some forms of food poisoning. Moreover, activation by a cytokine called LIGHT, which is a member of the...
6-Aug-2018 11:05 AM EDT Add to Favorites

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Maternal Dengue Immunity Protects Against Fetal Damage in Mice Following Zika Virus Infection

A mouse mother's prior dengue immunity would protects her unborn pups from devastating brain defects such as microencephaly associated with ZIKV. These findings could guide development of more effective flavivirus vaccines and hint at what types of...
30-Jul-2018 1:15 PM EDT Add to Favorites


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About

The La Jolla Institute for Immunology is dedicated to increasing knowledge and improving human health through studies of the immune system. Our essential purpose is to expand our understanding of how the immune system works and to discover the causes of immune system disorders. The knowledge gained through our biomedical research can, in turn lead to the prevention, treatment and cure of a wide range of human diseases.

Experts

  • Klaus Ley

    Professor

    Keywords:
    Inflammation, Heart Disease, Vaccine, chronic inflammation, Integrins
     
     
  • Pandurangan Vijayanand

    William K. Bowes Distinguished Professor

    Keywords:
    Asthma, PrecISE Clinical Center, Lung Cancer, immune fitness, immune profiling, Precision Medicine, genomic tools
     
     
  • Catherine Hedrick

    Professor

    Keywords:
    Monocytes, Cancer, Cardiovascular Disease, T Lymphocytes, cancer metastasis, Heart Disease, Plaques, Immune Cells
     
     
  • Shane Crotty

    Professor

    Keywords:
    Hiv Vaccine, human immune response, Vaccines, CHAVI-ID, Germinal Centers, neutralizing antibodies
     
     
  • Michael Croft

    Professor

    Keywords:
    Fibrosis, Atopic Dermatitis, Asthma, Eczema, Tumor Necrosis Factor, TNF, Inflammation, Light, TNF family, Autoimmune Disease, Psoriasis
     
     

Contacts

Gina Kirchweger
Chief Communications Officer
allergy immunology

858-752-6640

Jenna Hambrick
Digital Strategist

858.752.6645

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