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La Jolla, CA USA

Our News on Newswise

In Nepal with Dr. Melanie McCauley

”There's a lot of merit in bringing medicines to people who can't reach them themselves, but it's sort of putting a bandaid on the situation and I realized that only through scientific discovery will we really make huge changes that impact large...
16-May-2019 10:35 AM EDT Add to Favorites

Bill, the Carousel Guy

in 47 years operating the Balboa Park Carousel in San Diego, Bill Brown has only missed two weeks of work. For him, Life Without Disease means that he never has to miss another day.
16-May-2019 10:35 AM EDT Add to Favorites

On the road with Page and Larry

Page and Larry have been exploring the world together since their days as high school sweethearts. For them, Life Without Disease means they can keep going wherever adventure leads them.
15-May-2019 2:05 PM EDT Add to Favorites


New HIV vaccine strategy “pumps” the immune system

A new HIV vaccine delivery strategy appears to enhance the protective immune response in a preclinical model. Scientists at the La Jolla Institute for Immunology (LJI) have discovered that delivering an HIV vaccine in small doses over a series of...
6-May-2019 9:50 AM EDT Add to Favorites


TET gene mutations in T regulatory cells unleash fatal autoimmune disease in mice

When TET2 and TET3 proteins are genetically deleted from T-regs in mice, their suppressive function is lost over time and animals develop inflammatory disease. More importantly, because these TET2 and TET3 mutant cells had once 'experienced' being a...
30-Apr-2019 8:05 PM EDT Add to Favorites


TET proteins regulate factors essential for normal antibody production

A new report by researchers at La Jolla Institute found that a genetic deletion, or mutation, of TET2 and TET3 in mouse B cells damps down the generation of functional IgG antibodies, decreasing the effectiveness of immune responses.
24-Apr-2019 11:05 AM EDT Add to Favorites


To respond or tolerate? LJI researchers selectively block immune activation program orchestrated by the nuclear factor NFAT

The immune system occasionally makes mistakes that require correction. For example, in autoimmunity, T-cells lose "immune tolerance" of self and can destroy one's very own tissues. Conversely, in cancer, the immune system can rapidly exhaust itself...
22-Apr-2019 3:05 PM EDT Add to Favorites


Why your kid’s strep throat keeps coming back

Each year, some 600 million people around the world come down with strep throat. Yet, it was unclear why some kids are prone to repeated bouts of strep throat while others appear to be more or less immune. The latest study by researchers at La Jolla...
4-Feb-2019 7:00 AM EST Add to Favorites

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Our Experts on Newswise


Dr. Matthias von Herrath named world’s leading type 1 diabetes expert

Dr. Matthias von Herrath, M.D., who founded the Type 1 Diabetes Center at La Jolla Institute for Immunology (LJI) has been identified as the world’s top expert in Type 1 Diabetes by Expertscape, an organization that provides tools to quickly and...
12-Dec-2018 11:05 AM EST

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Our YouTube Videos


The La Jolla Institute for Immunology is dedicated to increasing knowledge and improving human health through studies of the immune system. Our essential purpose is to expand our understanding of how the immune system works and to discover the causes of immune system disorders. The knowledge gained through our biomedical research can, in turn lead to the prevention, treatment and cure of a wide range of human diseases.


  • Erica Ollmann Saphire


    Ebola, Lassa Fever, Marburg Hemorrhagic Fever, VIC, Ebola outbreak, Hemorrhagic Fever, Chikungunya, Ebola treatment, Lassa fever vaccine, cryo-electron microscopy, Structure, neutralizing antibodies, marburg virus
  • Klaus Ley


    Inflammation, Heart Disease, Vaccine, chronic inflammation, Integrins
  • Pandurangan Vijayanand

    William K. Bowes Distinguished Professor

    Asthma, PrecISE Clinical Center, Lung Cancer, immune fitness, immune profiling, Precision Medicine, genomic tools
  • Catherine Hedrick


    Monocytes, Cancer, Cardiovascular Disease, T Lymphocytes, cancer metastasis, Heart Disease, Plaques, Immune Cells
  • Shane Crotty


    Hiv Vaccine, human immune response, Vaccines, CHAVI-ID, Germinal Centers, neutralizing antibodies


Gina Kirchweger
Chief Communications Officer
allergy immunology


Jenna Hambrick
Digital Strategist


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