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Lassa Virus’ Soft Spot Revealed

A new study, led by researchers at La Jolla Institute for Immunology (LJI), identified and then reverse engineered the molecular properties shared by antibodies that are particularly efficient at inactivating or “neutralizing” Lassa virus...
5-Aug-2019 8:05 AM EDT Add to Favorites

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TET proteins: double agents in DNA methylation prevent catastrophic cancer

In their latest study, published in this week’s online issue of Proceedings of the National Academy of Sciences, researchers at La Jolla Institute for Immunology (LJI), reveal how the finely tuned balance between DNA methylation and demethylation...
24-Jul-2019 2:45 PM EDT Add to Favorites

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No cell is an island

In a new study, published on June 25, 2019, in the journal eLife, the researchers report that higher levels of doublets can be found in people with severe cases of tuberculosis or dengue fever.
24-Jun-2019 5:05 PM EDT Add to Favorites

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To kill tumors, activate this elite group of T cells

Tissue-resident memory T cells (TRMs) are known to help the body fight infection, but they are also key tumor fighters. A new study reveals that these cells are unique in their ability to seek out and kill tumor cells without suffering from the...
21-Jun-2019 5:05 PM EDT Add to Favorites

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Eric Zwisler named Chair of La Jolla Institute for Immunology’s Board of Directors

Eric Zwisler, former President and Chairman of Cardinal Health China, has been elected Chairman of the Board of Directors of La Jolla Institute for Immunology. He will assume his role effective May 31, 2019.
3-Jun-2019 3:05 PM EDT Add to Favorites

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NIH awards $35 million grant to establish global Consortium to develop treatments for Ebola, Lassa and other viral threats

La Jolla Institute Professor Erica Ollmann Saphire, Ph.D., will lead a five-year global effort totaling up to $35 million that brings together experts from around the world to streamline and accelerate the development of immunotherapeutics against...
27-May-2019 12:05 PM EDT Add to Favorites

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De-TOXing exhausted T cells may bolster CAR T immunotherapy against solid tumors

A decade ago researchers announced development of a cancer immunotherapy called CAR (for chimeric antigen receptor)-T, in which a patient is re-infused with their own genetically modified T cells equipped to mount a potent anti-tumor attack.
23-May-2019 4:05 AM EDT Add to Favorites

In Nepal with Dr. Melanie McCauley

”There's a lot of merit in bringing medicines to people who can't reach them themselves, but it's sort of putting a bandaid on the situation and I realized that only through scientific discovery will we really make huge changes that impact large...
16-May-2019 10:35 AM EDT Add to Favorites


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Our Experts on Newswise

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Dr. Matthias von Herrath named world’s leading type 1 diabetes expert

Dr. Matthias von Herrath, M.D., who founded the Type 1 Diabetes Center at La Jolla Institute for Immunology (LJI) has been identified as the world’s top expert in Type 1 Diabetes by Expertscape, an organization that provides tools to quickly and...
12-Dec-2018 11:05 AM EST

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About

The La Jolla Institute for Immunology is dedicated to increasing knowledge and improving human health through studies of the immune system. Our essential purpose is to expand our understanding of how the immune system works and to discover the causes of immune system disorders. The knowledge gained through our biomedical research can, in turn lead to the prevention, treatment and cure of a wide range of human diseases.

Experts

  • Catherine Hedrick

    Professor

    Keywords:
    Monocytes, Cancer, Cardiovascular Disease, T Lymphocytes, cancer metastasis, Heart Disease, Plaques, Immune Cells
     
     
  • Erica Ollmann Saphire

    Professor

    Keywords:
    Ebola, Lassa Fever, Marburg Hemorrhagic Fever, VIC, Ebola outbreak, Hemorrhagic Fever, Chikungunya, Ebola treatment, Lassa fever vaccine, cryo-electron microscopy, Structure, neutralizing antibodies, marburg virus
     
     
  • Klaus Ley

    Professor

    Keywords:
    Inflammation, Heart Disease, Vaccine, chronic inflammation, Integrins
     
     
  • Pandurangan Vijayanand

    William K. Bowes Distinguished Professor

    Keywords:
    Asthma, PrecISE Clinical Center, Lung Cancer, immune fitness, immune profiling, Precision Medicine, genomic tools
     
     
  • Shane Crotty

    Professor

    Keywords:
    Hiv Vaccine, human immune response, Vaccines, CHAVI-ID, Germinal Centers, neutralizing antibodies
     
     

Contacts

Gina Kirchweger
Chief Communications Officer
allergy immunology

gina@lji.org

858-752-6640

Jenna Hambrick
Digital Strategist

jhambrick@lji.org

858.752.6645

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