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Cellular culprit suspected of pushing dengue fever from bad to worse is cleared by advanced transcriptomics

No one knows what makes a mild dengue viral infection morph into a severe and sometimes deadly dengue hemorrhagic fever/dengue shock syndrome. Experts previously believed the likely cause was ramped up activity of T cells, which can massively boost...
19-Dec-2019 3:05 PM EST Add to Favorites

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La Jolla Institute for Immunology acquires Berkeley Lights Beacon® platform

La Jolla Institute for Immunology (LJI) is placing their confidence in Berkeley Lights’ Beacon® Optofluidic Platform and B cell antibody discovery workflow to accelerate the discovery of rare and lifesaving antibodies for the treatment of...
9-Dec-2019 1:00 AM EST Add to Favorites

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LJI researchers reveal unexpected versatility of an ancient DNA repair factor

New work from the lab of La Jolla Institute for Immunology (LJI) investigator Anjana Rao, Ph.D., reveals a previously unrecognized activity for a highly conserved DNA repair factor. The study reports that mouse lymphocytes engineered to lack that...
26-Nov-2019 4:35 PM EST Add to Favorites

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Seqster Signs 3-year License Agreement of SRP™ to La Jolla Institute of Immunology for Asthma Study

Seqster, the award-winning SaaS-based technology platform enabling consumer-centered health data management, today announced a 3-year licensing deal and partnership with La Jolla Institute of Immunology (LJI) to support the execution of a $6.9...
22-Oct-2019 11:30 AM EDT Add to Favorites

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Lassa Virus’ Soft Spot Revealed

A new study, led by researchers at La Jolla Institute for Immunology (LJI), identified and then reverse engineered the molecular properties shared by antibodies that are particularly efficient at inactivating or “neutralizing” Lassa virus...
5-Aug-2019 8:05 AM EDT Add to Favorites

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TET proteins: double agents in DNA methylation prevent catastrophic cancer

In their latest study, published in this week’s online issue of Proceedings of the National Academy of Sciences, researchers at La Jolla Institute for Immunology (LJI), reveal how the finely tuned balance between DNA methylation and demethylation...
24-Jul-2019 2:45 PM EDT Add to Favorites

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No cell is an island

In a new study, published on June 25, 2019, in the journal eLife, the researchers report that higher levels of doublets can be found in people with severe cases of tuberculosis or dengue fever.
24-Jun-2019 5:05 PM EDT Add to Favorites

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To kill tumors, activate this elite group of T cells

Tissue-resident memory T cells (TRMs) are known to help the body fight infection, but they are also key tumor fighters. A new study reveals that these cells are unique in their ability to seek out and kill tumor cells without suffering from the...
21-Jun-2019 5:05 PM EDT Add to Favorites


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Our Experts on Newswise

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Expert available to discuss Lassa virus and antibody therapies against the virus

26-Nov-2019 10:40 AM EST

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Dr. Matthias von Herrath named world’s leading type 1 diabetes expert

Dr. Matthias von Herrath, M.D., who founded the Type 1 Diabetes Center at La Jolla Institute for Immunology (LJI) has been identified as the world’s top expert in Type 1 Diabetes by Expertscape, an organization that provides tools to quickly and...
12-Dec-2018 11:05 AM EST

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About

The La Jolla Institute for Immunology is dedicated to increasing knowledge and improving human health through studies of the immune system. Our essential purpose is to expand our understanding of how the immune system works and to discover the causes of immune system disorders. The knowledge gained through our biomedical research can, in turn lead to the prevention, treatment and cure of a wide range of human diseases.

Experts

  • Catherine Hedrick

    Professor

    Keywords:
    Monocytes, Cancer, Cardiovascular Disease, T Lymphocytes, cancer metastasis, Heart Disease, Plaques, Immune Cells
     
     
  • Keywords:
    Ebola, Lassa Fever, Marburg Hemorrhagic Fever, VIC, Ebola outbreak, Hemorrhagic Fever, Chikungunya, Ebola treatment, Lassa fever vaccine, cryo-electron microscopy, Structure, neutralizing antibodies, marburg virus
     
     
  • Klaus Ley

    Professor

    Keywords:
    Inflammation, Heart Disease, Vaccine, chronic inflammation, Integrins
     
     
  • Pandurangan Vijayanand

    William K. Bowes Distinguished Professor

    Keywords:
    Asthma, PrecISE Clinical Center, Lung Cancer, immune fitness, immune profiling, Precision Medicine, genomic tools
     
     
  • Shane Crotty

    Professor

    Keywords:
    Hiv Vaccine, human immune response, Vaccines, CHAVI-ID, Germinal Centers, neutralizing antibodies
     
     

Contacts

Gina Kirchweger
Chief Communications Officer
allergy immunology

gina@lji.org

858-752-6640

Jenna Hambrick
Digital Strategist

jhambrick@lji.org

858.752.6645

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