T cells take the lead in controlling SARS-CoV-2 and reducing COVID-19 disease severity

A multi-layered, virus-specific immune response is important for controlling SARS-CoV-2 during the acute phase of the infection and reducing COVID-19 disease severity, with the bulk of the evidence pointing to a much bigger role for T cells than...
16-Sep-2020 2:55 PM EDT Add to Favorites

LJI scientists receive $3.5 million to investigate role of immune cells in Parkinson's disease

Scientists at the La Jolla Institute for Immunology (LJI) have received $3.5 million as part of a team award from Aligning Science Across Parkinson’s (ASAP) to support a three-year study into how immune cells may contribute to Parkinson's disease.
15-Sep-2020 1:45 PM EDT Add to Favorites

Beating HIV and COVID-19 may depend on tweaking vaccine molecules

In a new Immunity study, researchers at La Jolla Institute for Immunology (LJI) show that one way to improve the body's immune response to vaccines is to factor in antigen valency. Valency refers to the number of antibody binding sites on an antigen.
27-Aug-2020 3:45 PM EDT Add to Favorites

Blocking nerve signals to the pancreas halts type 1 diabetes onset in mice

Blocking nerve signals to the pancreas could stop patients from ever developing type 1 diabetes.
23-Aug-2020 9:00 PM EDT Add to Favorites

LJI team gets first-ever look at a rare but vital stem cell in humans

Scientists at La Jolla Institute for Immunology (LJI) have tracked down the rare stem cells that generate neutrophils in human bone marrow. This research, published August 18, 2020, in Immunity, gives researchers a potential path for intervening in...
14-Aug-2020 5:45 PM EDT Add to Favorites

Exposure to common cold coronaviruses can teach the immune system to recognize SARS-CoV-2

A new study led by scientists at La Jolla Institute for Immunology (LJI) shows that memory helper T cells that recognize common cold coronaviruses also recognize matching sites on SARS-CoV-2, the virus that causes COVID-19.
4-Aug-2020 10:00 AM EDT Add to Favorites

T cells can shift from helping to harming in atherosclerosis

At La Jolla Institute for Immunology (LJI) researchers are dedicated to finding a way to stop plaques from forming in the first place. In a new study, LJI scientists show that certain T lymphocytes, a type of white blood cell, that start out trying...
22-Jul-2020 8:05 PM EDT Add to Favorites

Researchers track down metabolic enzyme that protects against inflammation

A new study from scientists at the La Jolla Institute for Immunology (LJI) shows that a previously poorly understood enzyme actually inhibits inflammation in blood vessels. The research offers a potential path to treating DADA2, an inflammatory...
17-Jul-2020 2:20 PM EDT Add to Favorites

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