Moffitt Researchers Develop Non-invasive Approach to Measure Biomarker Levels, Predict Outcomes in Lung Cancer Patients

In a new article published in the Journal for ImmunoTherapy of Cancer, Moffitt Cancer Center researchers show that PET/CT images can be used to measure levels of the PD-L1 biomarker of non-small cell lung cancer (NSCLC) patients in a non-invasive...
17-Jun-2021 11:35 AM EDT Add to Favorites

Analyzing the Tumor Microenvironment at the Single Cell Level Sheds Light on Metastatic Melanoma Outcomes, Moffitt Study Shows

In a new article published in Clinical Cancer Research, Moffitt Cancer Center researchers reveal how different therapies impact the surrounding immune environment of metastatic melanoma tumors according to location and identify a rare population of...
3-Jun-2021 2:10 PM EDT Add to Favorites

Moffitt Cancer Center Experts to Present New Clinical Research Data

Moffitt Cancer Center, a national leader in cancer care and research and the only National Cancer Institute-designated Comprehensive Cancer Center based in Florida, is presenting new data from dozens of clinical research studies at this year’s...
1-Jun-2021 9:25 AM EDT Add to Favorites

Mutation Profile of Acral Nevi Differs from Acral Melanoma, Moffitt Researchers Say

In a new study published in JAMA Dermatology, Moffitt Cancer Center researchers report on the mutation profile of acral nevi and describe differences between acral nevi and acral melanoma.
12-May-2021 1:05 PM EDT Add to Favorites

Moffitt Researchers Discover Regulatory Pathway That Blocks Immune Response Against Cancer

In a new article published in the journal Immunity, Moffitt Cancer Center researchers show that TIM-3 inhibits the STING signaling pathway in dendritic cells, thereby blocking their ability to elicit an immune response.
11-May-2021 11:15 AM EDT Add to Favorites

Moffitt Investigators Identify Sting Gene Methylation That Allows Melanoma to Evade the Immune System

A dysfunctional immune system significantly contributes to the development of cancer. Several therapeutic strategies to activate the immune system to target cancer cells have been approved to treat different types of cancer, including melanoma.
8-Apr-2021 8:05 AM EDT Add to Favorites

Moffitt Researchers Demonstrate Tissue Architecture Regulates Tumor Evolution Location Matters

In a new article published in Nature Communications, Moffitt Cancer Center researchers show how the location of the tumor and spatial constraints put on it by the surrounding tissue architecture impact genetic heterogeneity of tumors.
6-Apr-2021 9:50 AM EDT Add to Favorites

Moffitt Researchers Use Mathematical Modeling to Analyze Dynamics of CAR T-Cell Therapy

In an article published in Proceedings of the Royal Society B, Moffitt Cancer Center researchers use mathematical modeling to help explain why CAR T cells work in some patients and not in others.
25-Mar-2021 10:20 AM EDT Add to Favorites

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