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Phase 3 Trial Finds Oral Empagliflozin Provided Safe Glycemic Control in Children with Type 2 Diabetes

Researchers recently completed a phase 3 clinical trial that assessed the efficacy and safety of two different classes of oral agents for the treatment of type 2 diabetes in young people aged 10-17 years.
23-Feb-2023 2:55 PM EST Add to Favorites

Researchers Shed Light on How Exercise Preserves Physical Fitness During Aging

Researchers investigated the role of one cellular mechanism in improving physical fitness by exercise training and identified one anti-aging intervention that delayed the declines that occur with aging in the model organism.
5-Jan-2023 1:55 PM EST Add to Favorites

Exercise and obesity have opposite impact on muscle, fat tissues, researchers demonstrate

First-of-its-kind dissection of adipose and muscle tissues reveal single-cell changes in metabolic tissues
5-Oct-2022 2:15 PM EDT Add to Favorites

Study Reverses Long-Held Ideas About Relationship Among Diabetes, Fat and Cardiovascular Disease

In a paper published in Circulation Research, scientists describe a series of studies designed to determine the relationship among insulin, fats and the vascular system.
5-Aug-2022 10:35 AM EDT Add to Favorites

Gut Microbe Peptide Implicated in Triggering Type 1 Diabetes

Researchers have identified a species of human gut bacterium that makes a protein containing a sequence of amino acids that mimics the insulin peptide targeted by the immune system in type 1 diabetes.
25-Jul-2022 5:40 PM EDT Add to Favorites

Crosstalk between pancreatic cells may drive rare form of diabetes

Joslin researchers show how one form of the rare inherited disease known as mature onset diabetes of the young (MODY) is driven by mutated digestive enzymes generated in pancreatic exocrine cells that are then taken up by neighboring...
20-Jan-2022 2:05 PM EST Add to Favorites

Cracking the code for a new system of cell-to-cell signaling

Joslin discovery about exosomes (cell fragments that regulate other cells) may help to advance RNA gene therapies for many diseases.
22-Dec-2021 4:10 PM EST Add to Favorites

Insulin resistance pinned to cell signaling defects that could act as therapy targets

Insulin resistance in the general population seems likely to be caused by a series of cell-specific signaling defects some of which appear to be sex-specific. In addition, only a portion of the defects are shared with those seen in diabetes,...
20-Sep-2021 7:05 AM EDT Add to Favorites


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Back to School with Dr. Lori Laffel from Joslin Diabetes Center

Lori Laffel, M.D., MPH, Chief of the Pediatric, Adolescent and Young Adult Section at Joslin Diabetes Center and Associate Professor of Pediatrics at Harvard Medical School, oversees the largest pediatric diabetes clinic in New England has over 25...
15-Aug-2014 8:00 AM EDT

Expert Available: Bariatric Surgery for Diabetes

The International Diabetes Federation now recommends that surgery be considered as a treatment for obese patients with type 2 diabetes. Dr. Allison Goldfine, head of clinical research at Joslin Diabetes Center, is available for comment.
29-Mar-2011 9:00 AM EDT

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Joslin Diabetes Center is world-renowned for its deep expertise in diabetes treatment and research. Joslin is dedicated to finding a cure for diabetes and ensuring that people with diabetes live long, healthy lives. We develop and disseminate innovative patient therapies and scientific discoveries throughout the world. Joslin is an independent, non-profit institution affiliated with Harvard Medical School, and one of only 16 NIH-designated Diabetes Research Centers in the U.S.

For more information, visit www.joslin.org or follow @joslindiabetes

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Jeff Bright
Director, Communications

jeffrey.bright@joslin.harvard.edu

617-309-1957

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