David   Rimm, MD, PhD

David Rimm, MD, PhD

Yale Cancer Center/Smilow Cancer Hospital

Anthony N. Brady Professor of Pathology and Professor of Medicine (Medical Oncology); Director, Yale Cancer Center Tissue Microarray Facility, Pathology; Director, Yale Pathology Tissue Services, Pathology; Director, Physician Scientist Training Program, Pathology Research

Expertise: Breast CancerTargeted TherapiesPathologyCancer Cells

David Rimm is the Anthony N. Brady Professor of Pathology in the Departments of Pathology and Medicine (Oncology) at the Yale University School of Medicine. He is the Director of Yale Pathology Tissue Services and the Lab for Quantitative Diagnostics in Anatomic Pathology. He completed an MD-PhD at Johns Hopkins University Medical School followed by a Pathology Residency at Yale and a Cytopathology Fellowship at the Medical College of Virginia. His research lab group focuses on quantitative pathology using the AQUA® technology invented in his lab, and other quantitative methods, with projects related to predicting response and resistance to both targeted and immune- therapy in cancer. His lab is involved in the use of new high-plex methods including digital spatial profiling (NanoString) for new biomarker discovery. He is also interested in translation of assays to the clinic and standardization of those assays for CLIA labs. The work is supported by grants from the NIH, BCRF, and sponsored research agreements from biopharma. He also serves on the CAP Immunohistochemistry committee and multiple scientific advisory boards for biotech and pharma. He is an author of over 500 peer-reviewed papers with an H-index of 120 and 8 patents.

No Research/Citations

Study: New Biomarker Tool Helps Select Targeted Therapies to Treat Metastatic Breast Cancers

Two antibody drug conjugates (ADCs), trastuzumab deruxtecan (T-DXd) and sacituzumab govitecan (SG), were approved by the FDA to treat metastatic breast cancers. ADCs are a type of targeted therapy that release cancer drugs to specific tumor cells. The efficacy of T-DXd and SG depends on target expression and the best method for measuring that expression is still not known.
04-Dec-2023 03:05:28 PM EST

No Quotes

Available for logged-in users onlyLogin HereorRegister

No Video

close
0.07326