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Released: 13-Apr-2016 11:05 AM EDT
Method for Earlier Detection of Leukemia Wins $300,000 Grant
Koch Institute for Integrative Cancer Research at MIT

A team of MIT researchers received a $300,000 grant to develop a new diagnostic program that could detect leukemia at its earliest stages.

27-Oct-2015 3:05 PM EDT
$20 Million Commonwealth Foundation for Cancer Research Challenge Gift to Expand Collaborative Cancer Research Between Dana-Farber/Harvard Cancer Center and MIT’s Koch Institute
Koch Institute for Integrative Cancer Research at MIT

The Commonwealth Foundation for Cancer Research has pledged $20 million to the Bridge Project, a collaborative research program of the Koch Institute for Integrative Cancer Research at MIT and Dana-Farber/Harvard Cancer Center (DF/HCC), to accelerate the translation of interdisciplinary cancer solutions toward the clinic.

Released: 18-Aug-2015 11:05 AM EDT
MIT Koch Institute’s Canan Dagdeviren Recognized as Honoree of MIT Technology Review’s Annual "Innovators Under 35" List
Koch Institute for Integrative Cancer Research at MIT

Today, MIT Technology Review reveals its annual list of Innovators Under 35. The list represents exceptionally talented technologists whose work has great potential to transform the world. For her work in the field of nanotechnology and materials, Canan Dagdeviren of MIT’s Koch Institute has been recognized as an inventor on the list.

Released: 4-Aug-2015 2:05 PM EDT
Real-Time Data for Cancer Therapy
Koch Institute for Integrative Cancer Research at MIT

Researchers at MIT’s Koch Institute for Integrative Cancer Research are developing a tiny biochemical sensor that can be implanted in cancerous tissue during initial biopsy. The sensor wirelessly sends data about telltale biomarkers to an external “reader” device, allowing doctors to better monitor a patient’s progress and adjust dosages or switch therapies accordingly.

Released: 30-Jul-2015 12:05 PM EDT
Identifying a Key Growth Factor in Cell Proliferation
Koch Institute for Integrative Cancer Research at MIT

In two companion papers published in Cell, researchers from MIT's Koch Institute reveal why proliferating cells — including those in tumors — require mitochondrial respiration. While there are other ways to make ATP, cells can’t proliferate without access to electron acceptors provided by respiration.

23-Jul-2015 12:05 PM EDT
New Material Opens Possibilities for Super-Long-Acting Pills
Koch Institute for Integrative Cancer Research at MIT

Researchers at MIT’s Koch Institute for Integrative Cancer Research and Massachusetts General Hospital have created a polymer gel that could allow for the development of long-acting devices that reside in the stomach, including orally delivered capsules that can release drugs over a number of days, weeks, or potentially months following a single administration.

Released: 4-Jun-2015 10:05 AM EDT
MIT’s Koch Institute Hosts 14th Annual Symposium, “CANCER COMPLEXITY: Heterogeneity in Tumor Progression and Drug Response”
Koch Institute for Integrative Cancer Research at MIT

This one-day symposium at MIT will examine the heterogeneity within tumors that shape their evolutions and allow them to resist treatments. Nearly 1,000 cancer researchers and clinical oncologists will assemble to learn about the latest breakthroughs in overcoming the clinical challenges this complexity creates for cancer diagnostics and therapy.

Released: 27-May-2015 2:05 PM EDT
Diagnosing Cancer with Help From Bacteria
Koch Institute for Integrative Cancer Research at MIT

Engineers at MIT and the University of California at San Diego have devised a new way to detect cancer that has spread to the liver, by enlisting help from probiotics — beneficial bacteria similar to those found in yogurt.

21-May-2015 10:05 AM EDT
Microfluidic Cell-Squeezing Device Opens New Possibilities for Cell-Based Vaccines
Koch Institute for Integrative Cancer Research at MIT

MIT researchers have shown that they can use a microfluidic cell-squeezing device to introduce specific antigens inside the immune system’s B cells, providing a new approach to developing and implementing antigen-presenting cell vaccines.

Released: 20-May-2015 5:05 PM EDT
Tyler Jacks Receives MIT Faculty's Top Honor
Koch Institute for Integrative Cancer Research at MIT

Tyler Jacks, a pioneering cancer biologist and director of MIT’s Koch Institute for Integrative Cancer Research, is this year’s recipient of MIT’s James R. Killian Jr. Faculty Achievement Award. The Killian Award is the highest honor MIT grants to members of its faculty.

Released: 13-May-2015 9:05 AM EDT
Faster, Smaller, More Informative
Koch Institute for Integrative Cancer Research at MIT

A new technique invented at MIT can measure the relative positions of tiny particles as they flow through a fluidic channel, potentially offering an easy way to monitor the assembly of nanoparticles, or to study how mass is distributed within a cell. With further advancements, this technology has the potential to resolve the shape of objects in flow as small as viruses, the researchers say.

Released: 22-Apr-2015 2:05 PM EDT
How to Identify Drugs That Work Best for Each Patient
Koch Institute for Integrative Cancer Research at MIT

More than 100 drugs have been approved to treat cancer, but predicting which ones will help a particular patient is an inexact science at best. A new implantable device developed at MIT may change that.

Released: 9-Apr-2015 9:05 AM EDT
Biologists Identify Brain Tumor Weakness
Koch Institute for Integrative Cancer Research at MIT

A study led by MIT researchers found that a subset of glioblastoma tumor cells is dependent on a particular enzyme that breaks down the amino acid glycine. Without this enzyme, toxic metabolic byproducts build up inside the tumor cells, and they die. Blocking this enzyme could offer a new way to combat such tumors.

Released: 7-Apr-2015 9:00 AM EDT
Cerebral Curiosity
Koch Institute for Integrative Cancer Research at MIT

Steven Keating's curiosity led to the detection of a baseball-sized brain tumor and sparked an interest into the potential of open health data to help himself and others.

Released: 19-Feb-2015 1:00 PM EST
New Nanogel for Drug Delivery
Koch Institute for Integrative Cancer Research at MIT

MIT chemical engineers have designed a new type of self-healing hydrogel that could be injected through a syringe. Such gels, which can carry one or two drugs at a time, could be useful for treating cancer, macular degeneration, or heart disease, among other diseases, the researchers say.

Released: 10-Feb-2015 10:00 AM EST
Engineered Insulin Could Offer Better Diabetes Control
Koch Institute for Integrative Cancer Research at MIT

MIT engineers hope to improve treatment for diabetes patients with a new type of engineered insulin. In tests in mice, the researchers showed that their modified insulin can circulate in the bloodstream for at least 10 hours, and that it responds rapidly to changes in blood-sugar levels.

Released: 3-Dec-2014 2:05 PM EST
A Light-Triggered Approach to Aptamer-Based Cancer Therapeutics
Koch Institute for Integrative Cancer Research at MIT

Researchers at MIT's Koch Institute and Boston Children’s Hospital describe how a new light-triggered strategy can provide more accurate control over where aptamers accumulate.

Released: 18-Nov-2014 10:00 AM EST
Immunologist Herman Eisen Dies at 96
Koch Institute for Integrative Cancer Research at MIT

Immunologist Herman Eisen, founding member of the MIT Center for Cancer Research, died Nov. 2 at age 96. He is perhaps best known for his early work in describing affinity maturation.

Released: 17-Nov-2014 7:05 PM EST
Sangeeta Bhatia Named One of Foreign Policy's 100 Leading Global Thinkers
Koch Institute for Integrative Cancer Research at MIT

Koch Institute faculty member Sangeeta Bhatia has been selected as one of Foreign Policy magazine’s 100 Leading Global Thinkers of 2014 for her work in developing inexpensive and noninvasive diagnostics for the early detection of colon cancer.

Released: 22-Oct-2014 3:00 PM EDT
Fast Modeling of Cancer Mutations
Koch Institute for Integrative Cancer Research at MIT

Using CRISPR, researchers at MIT's Koch Institute have developed a new approach to rapidly model the effects of tumor cells’ genetic mutations in mice.



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