Searching for ways to extend the survival benefit of targeted therapies, a team led by researchers at the Duke Cancer Institute identified a potential new tactic to disrupt the repair mechanism that cancer cells use after treatment, blunting their ability to regenerate. The approach could present a new treatment strategy.
Using mRNA technology like that in the COVID-19 vaccines, researchers have demonstrated a successful way to deliver a potential HIV vaccine, researchers at Duke Human Vaccine Institute report.
School districts that required masking saw lower rates of COVID-19 transmission within schools last fall compared to those with optional masking policies, according to a study by the ABC Science Collaborative.
Health care workers who have children under age 5 are twice as likely as other parents to plan to vaccinate their children against COVID-19, according to a new poll conducted by the HERO Registry, which is coordinated by the Duke Clinical Research Institute.
A study led by the Duke Clinical Research Institute (DCRI) in partnership with Vanderbilt University has expanded its testing platform to evaluate ivermectin at a higher dose for a longer period of time.
MRI scans of children aged 9–10 years with ADHD showed few differences in structural brain measurements compared to their unaffected peers, according to a study led by a Duke University School of Medicine researcher.
Cognitive changes following non-neurologic and non-cardiac surgery were not associated with changes in Alzheimer’s disease-related biomarkers in older patients, according to a study led by a team at Duke University School of Medicine.
Hospital rooms where COVID patients were treated had little to no active virus contaminations on surfaces, according to a study at Duke University Hospital that adds to the body of research on how the pandemic respiratory virus is spread.
Some prostate cancers might also include a small number of aggressive cells hiding among the indolent ones like wolves in a herd of sheep. Researchers at Duke Health have identified a molecular signature that can spot these lurking threats.
the NIH Collaboratory is donning a new name—NIH Pragmatic Trials Collaboratory—that will carry the highly successful program into the future with a continued commitment to transforming clinical research. The program was formerly known as the NIH Health Care Systems Research Collaboratory. Its new moniker reflects the program’s core mission of strengthening the national capacity to implement cost-effective, large-scale research studies conducted within healthcare delivery systems, also known as pragmatic trials.
Children and staff who repeatedly test negative for COVID-19 after contact with someone who has the illness can safely remain in school if universal masking programs are in place, according to a new “test-to-stay” study report from the ABC Science Collaborative.
With numerous recent studies demonstrating that antibiotics work as well as surgery for most uncomplicated appendicitis cases, the non-surgical approach can now be considered a routine option, according to a review article in JAMA.
The National Institute of Allergy and Infectious Diseases awarded researchers at the Duke Human Vaccine Institute a contract that enables it to compete for projects advancing investigational vaccines to production for use in early clinical trials.
The Duke Clinical Research Institute (DCRI), Center for Health Equity Research at UNC-Chapel Hill (UNC-CHER), and Community-Campus Partnerships for Health (CCPH) today announced plans to deliver their You & Me COVID-Free testing project in Merced County, Calif., in partnership with United Way.
A survey of parents and caregivers of children with cancer found that nearly a third of them expressed hesitancy to vaccinate their youngsters against COVID-19.
In a large national survey, adults who struggled with picky eating habits as children overwhelmingly said they benefitted more from positive and encouraging strategies their parents used than forceful or coercive approaches.
Duke’s accountable care organization received a 96.88% quality score in the most recent assessment from the Centers for Medicare and Medicaid Services (CMS).
A research collaboration between scientists at Duke University and the University of North Carolina at Chapel Hill has identified and tested an antibody that limits the severity of infections from a variety of coronaviruses, including those that cause COVID-19 as well as the original SARS illness.
Craig Albanese, a seasoned health care executive and distinguished academic pediatric surgeon, has been named executive vice president and chief operating officer of Duke University Health System (DUHS).
The National Institute of Allergy and Infectious Diseases (NIAID) has awarded $17.5 million over three years to the Duke Human Vaccine Institute to develop a vaccine that protects against multiple types of coronaviruses and viral variants.
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