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Hospitalized COVID-19 patients have a greater risk of dying if they are men or are obese or have complications from diabetes or hypertension, according to a new study conducted by University of Maryland School of Medicine (UMSOM) researchers. In a study published in the journal Clinical Infectious Diseases, the researchers evaluated nearly 67,000 hospitalized COVID-19 patients in 613 hospitals across the country to determine link between common patient characteristics and the risk of dying from COVID-19.

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Researchers at the University of Maryland School of Medicine published one of the most comprehensive analyses of how genes get expressed during infection (known as a transcriptome). The analyses include three different strains of the bacteria Streptococcus pneumoniae, which causes pneumonia, meningitis and middle-ear infections.

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Researchers at the University of Maryland School of Medicine (UMSOM) have discovered new drug compounds to potentially treat the novel coronavirus that causes COVID-19. This finding could lead to the development of new broad-spectrum antiviral drugs that target viruses such as influenza, Ebola and coronaviruses.

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Hospitalized COVID-19 patients who were taking a daily low-dose aspirin to protect against cardiovascular disease had a significantly lower risk of complications and death compared to those who were not taking aspirin, according to a new study led by researchers at the University of Maryland School of Medicine (UMSOM).

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Use of preventive antimalarial treatments reduces by half the number of malaria infections among schoolchildren, according to a new analysis published today in The Lancet Global Health.

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New research finds wide variations in the way hospitals ensure that premature or low birth weight infants can breathe safely in a car seat before they're discharged. The same infant who passes a screening in one hospital’s newborn nursery may fail in similar facilities at another hospital’s nursery.

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Researchers at the University of Maryland School of Medicine (UMSOM) have developed a novel technology to test for the presence of thin membrane protrusions called “microtentacles” on breast cancer cells, which can help predict whether a tumor is likely to spread. They describe the TetherChip device in a new paper published today in the Royal Society of Chemistry journal Lab on a Chip.

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Researchers at the University of Maryland School of Medicine (UMSOM) have for the first time identified stem cells in the region of the optic nerve, which transmits signals from the eye to the brain. The finding presents a new theory on why the most common form of glaucoma may develop and potential for new therapies.

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University of Maryland School of Medicine (UMSOM) Dean, E. Albert Reece, MD, PhD, MBA, and Christine Lau, MD, MBA, The Dr. Robert W. Buxton Chair of Surgery at UMSOM, announced today the hiring of two internationally-renown transplant professionals: a surgeon scientist and a transplant scientist. The unique pair of transplant professionals provides UMSOM with a powerful combination of leadership in both clinical surgery and surgical science.

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Researchers at the University of Maryland School of Medicine (UMSOM) evaluated several human antibodies to determine the most potent combination to be mixed in a cocktail and used as a promising anti-viral therapy against the virus that causes COVID-19.

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The Institute of Human Virology (IHV) at the University of Maryland School of Medicine, a Global Virus Network (GVN) Center of Excellence, in collaboration with scientists from Campus Biomedico in Rome and Ulisse Biomed and University of Trieste, in Trieste, Italy announced today the results of studies showing an inverse correlation between average high daily temperatures and COVID-19 related death rates in different geographical areas.

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Fentanyl is not typically part of hospital tests for illicit drug use, however, a new University of Maryland study found after expanding testing that fentanyl, linked to most fatal overdoses in Maryland, tops the list of drugs detected in overdose patients at two Baltimore hospital ERs. The researchers suggest addition of fentanyl to routine drug tests.

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Researchers at the University of Maryland School of Medicine (UMSOM) have identified how certain gene mutations cause amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. The finding could offer potential new approaches for treating this devastating condition.

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The Center for International Health, Education and Biosecurity (Ciheb) at the University of Maryland School of Medicine’s Institute of Human Virology was awarded $4 million from the U.S. Centers for Disease Control and Prevention (CDC) to support coronavirus disease 2019 (COVID-19) response activities in Botswana, Nigeria, Malawi, and Mozambique.

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A new landmark study by researchers at the University of Maryland School of Medicine (UMSOM) found that patients with a vascular condition, called abdominal aortic aneurysm, received no benefits from taking a common antibiotic drug to reduce inflammation.

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Researchers from the Center for Precision Disease Modeling at the University of Maryland School of Medicine (UMSOM) have uncovered a mechanism that appears to explain how certain genetic mutations give rise to a rare genetic kidney disorder called nephrotic syndrome. Using a drosophila (fruit fly) model, they found mutations in genes that code for certain proteins lead to a disruption of the recycling of the cell membrane.

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Prolonged fear and anxiety brought on by major stressors, like the coronavirus pandemic, can not only take a toll on a person’s mental health, but may also have a lasting impact on a man’s sperm composition that could affect his future offspring. That is the finding of a provocative new study published in the journal Nature Communications by researchers at the University of Maryland School of Medicine.

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Researchers at the University of Maryland School of Medicine’s Institute of Human Virology (IHV), which is part of the Global Virus Network (GVN), predict that COVID-19 will follow a seasonal pattern similar to other respiratory viruses like seasonal flu. They base this on weather modeling data in countries where the virus has taken hold and spread within the community.

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Using a combination of magnetic resonance imaging (MRI) to target and sample suspicious prostate tissue, along with a standard prostate biopsy, is significantly more likely to detect the most aggressive prostate cancers than standard biopsy alone. This finding, published today in the New England Journal of Medicine, could allow a higher percentage of prostate cancer patients to avoid unnecessary treatment for slow-growing prostate cancers that are not likely to spread.

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Researchers at the University of Maryland School of Medicine (UMSOM) found that targeting overactive immune cells in the brain with an experimental drug could limit brain cell loss and reverse cognitive and motor difficulties caused by traumatic brain injury (TBI).