Latest News from: JAMA - Journal of the American Medical Association

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7-Jun-2007 4:15 PM EDT
Physician-Researchers Often Less Successful in Obtaining NIH Funding
JAMA - Journal of the American Medical Association

Physician researchers with only an M.D. degree are less likely to receive NIH research grants than researchers with a Ph.D. degree or those with both M.D. and Ph.D. degrees, according to a study in the June 13 issue of JAMA.

7-Jun-2007 6:20 PM EDT
Diabetes Associated With Decreases in Life Expectancy and Number of Years Free of Heart Disease
JAMA - Journal of the American Medical Association

Men and women with diabetes at age 50 and older appear not to live as long overall, or have as many years without cardiovascular disease, than individuals without diabetes, according to a report in the June 11 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

7-Jun-2007 6:25 PM EDT
Studies Identify Interactions Between Heart Disease, Kidney Disease
JAMA - Journal of the American Medical Association

Anemia and other conditions related to chronic kidney disease are independently associated with the risk of cardiovascular disease; conversely, heart disease is associated with a decline in kidney function and the development of kidney disease, according to two reports in the June 11 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

7-Jun-2007 6:30 PM EDT
Survey: Most Patients Want to Shake Hands With Their Physicians
JAMA - Journal of the American Medical Association

Most patients want physicians to shake their hands when they first meet, and about half want their first names used in greetings, according to a report in the June 11 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

7-Jun-2007 6:40 PM EDT
Addressing Multiple Unhealthy Behaviors at Once May Be More Effective Than Sequential Approach
JAMA - Journal of the American Medical Association

Physicians trying to help patients change more than one behavioral risk factor may have more success approaching several topics at once rather than addressing them separately over time, according to a report in the June 11 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

7-Jun-2007 6:45 PM EDT
Blood Pressure Drop During Bypass Surgery Associated With Increased Risk of Cognitive Decline
JAMA - Journal of the American Medical Association

Patients whose mean arterial blood pressure drops during bypass surgery may be at risk for early difficulties in thinking, learning and memory, according to an article posted online today that will appear in the August 2007 print issue of Archives of Neurology, one of the JAMA/Archives journals.

31-May-2007 4:25 PM EDT
Folic Acid Supplements Do Not Appear to Reduce Risk of Colorectal Tumors
JAMA - Journal of the American Medical Association

New research indicates that folic acid supplementation does not decrease the risk of benign colorectal tumors, but may possibly increase the risk for some types of colorectal tumors, according to a study in the June 6 issue of JAMA. Some previous studies have suggested that folate supplementation may help to prevent colorectal tumors.

31-May-2007 4:30 PM EDT
Financial Incentives For Hospitals Not Associated With Improved Quality Of Care or Outcomes For Heart Attack Patients
JAMA - Journal of the American Medical Association

A pay-for-performance program at hospitals was not associated with significant improvement in processes of care or outcomes for heart attack patients, according to a study in the June 6 issue of JAMA.

31-May-2007 5:05 PM EDT
Low Doses of Ecstasy Associated With Decline in Verbal Memory
JAMA - Journal of the American Medical Association

Even low doses of Ecstasy may be associated with a decline in language-related memory, according to a report in the June issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

31-May-2007 5:20 PM EDT
Genetic Variations May Predispose Some Men to Suicidal Thoughts During Short-Term Treatment for Depression
JAMA - Journal of the American Medical Association

Genetic variations may help explain why some men with depression develop suicidal thoughts and behaviors after they begin taking antidepressant medications, while most do not, according to a report in the June issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

31-May-2007 4:00 PM EDT
Genetic Mutations Identified for Type of Gastric Cancer
JAMA - Journal of the American Medical Association

Researchers have identified novel genetic mutations that are linked to hereditary diffuse gastric cancer, with these mutations being due to both independent mutational events and common ancestry, according to a study in the June 6 issue of JAMA. This study is being released early to coincide with its presentation at the annual meeting of the American Society of Clinical Oncology.

24-May-2007 4:00 PM EDT
Intake of Vitamin D, Calcium Associated With Lower Risk of Breast Cancer Before Menopause
JAMA - Journal of the American Medical Association

Women who consume higher amounts of calcium and vitamin D may have a lower risk of developing premenopausal breast cancer, according to a report in the May 28 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

24-May-2007 4:00 PM EDT
Exercise May Slightly Boost "Good" Cholesterol Levels
JAMA - Journal of the American Medical Association

Regular exercise appears to modestly increase levels of high-density lipoprotein, or "good," cholesterol, according to a meta-analysis study in the May 28 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

24-May-2007 4:05 PM EDT
Soy Nuts May Improve Blood Pressure in Postmenopausal Women
JAMA - Journal of the American Medical Association

Substituting soy nuts for other protein sources in a healthy diet appears to lower blood pressure in postmenopausal women, and also may reduce cholesterol levels in women with high blood pressure, according to a report in the May 28 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

24-May-2007 4:10 PM EDT
Community-Associated Staph Infections Involving Antibiotic-Resistant Bacteria Increase
JAMA - Journal of the American Medical Association

The incidence of antibiotic-resistant staph infections associated with being acquired in the community and not in health care institutions increased almost seven-fold in Chicago's Cook County Hospital system between 2000 and 2005, according to a report in the May 28 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

17-May-2007 4:00 PM EDT
Certain Combination Therapy Found More Effective for Treating Malaria in African Children
JAMA - Journal of the American Medical Association

Ugandan children who received the combination therapy of artemether-lumefantrine experienced a lower rate of treatment failure compared to other combination therapies, according to a study in the May 23/30 issue of JAMA, a theme issue on malaria.

17-May-2007 4:10 PM EDT
Diagnostic Tests for Malaria Underused in Zambia
JAMA - Journal of the American Medical Association

Despite improvements in the ability to diagnose malaria, these diagnostic tests are often underused in Zambia, and patients with negative test results are often prescribed anti-malaria medications, according to a study in the May 23/30 issue of JAMA, a theme issue on malaria.

17-May-2007 4:20 PM EDT
Article Outlines Current Recommendations For Treating Malaria in the U.S.
JAMA - Journal of the American Medical Association

Kevin S. Griffith, M.D., M.P.H., of the Centers for Disease Control and Prevention, Atlanta, and colleagues conducted a review of medical literature from 1966 to 2006 to provide clinicians with recommendations for diagnosing and treating malaria in the U.S.

17-May-2007 4:20 PM EDT
Number of Insecticide-Treated Nets Available to African Households Needs to be Dramatically Increased
JAMA - Journal of the American Medical Association

John M. Miller, M.P.H., of the Malaria Control and Evaluation Partnership in Africa (MACEPA) at PATH, Lusaka, Zambia, and colleagues conducted a study to estimate how many insecticide-treated nets (ITNs) are available in African households that are at risk of malaria and how many ITNs are needed to reach targets for use by children younger than 5 years and pregnant women.

17-May-2007 4:35 PM EDT
Nearly Half of Children in Kenya With Common Type of Severe Malaria Affected Neurologically
JAMA - Journal of the American Medical Association

Richard Idro, M.M.E.D., of the Kenya Medical Research Institute, Kilifi, Kenya and colleagues conducted a study to determine the incidence and neurological involvement of African children with acute falciparum malaria (a severe type of malaria).

17-May-2007 5:15 PM EDT
Antifolate Therapies Found Effective Against Certain Type of Malaria
JAMA - Journal of the American Medical Association

Toby Leslie, M.Sc., of HealthNet TPO Malaria and Leishmaniasis Control Programme, Peshawar, Northwest Frontier Province, Pakistan, and colleagues tested the relative efficacy and safety of two antifolate drugs (sulfadoxine-pyrimethamine and chlorproguanil-dapsone) against P vivax malaria and compared each with chloroquine.

17-May-2007 5:25 PM EDT
Malaria 2007--Progressing Research, Persisting Challenges
JAMA - Journal of the American Medical Association

In an editorial in this week's JAMA, Gianna Zuccotti, M.D., Contributing Editor, and Catherine D. DeAngelis, M.D., M.P.H., Editor in Chief, JAMA, comment on the status of malaria in the world today.

10-May-2007 4:00 PM EDT
Low Amounts of Physical Activity Can Help Improve Fitness Levels For Sedentary, Overweight Postmenopausal Women
JAMA - Journal of the American Medical Association

New research indicates that even small amounts of physical activity, approximately 75 minutes a week, can help improve the fitness levels for postmenopausal women who are sedentary and overweight or obese, according to a study in the May 16 issue of JAMA.

10-May-2007 4:00 PM EDT
Low-Glycemic Load Diet May Be More Effective For Dieters With Certain Insulin Response Patterns
JAMA - Journal of the American Medical Association

Overweight individuals who secrete insulin at a higher level may experience greater weight loss by selecting a low-glycemic load diet, compared to a low-fat diet, according to a study in the May 16 issue of JAMA. The researchers also found a low-glycemic load diet to have beneficial effects on HDL cholesterol and triglyceride concentrations.

10-May-2007 4:00 PM EDT
Genetic Markers in Surrounding Tissues Associated With Breast Cancer Tumor Grade, Presence of Metastases
JAMA - Journal of the American Medical Association

Researchers have identified genetic markers on several chromosomes in the tissue surrounding tumor cells that are associated with breast cancer tumor grade and the presence of lymph node metastases, according to a study in the May 16 issue of JAMA.

10-May-2007 5:40 PM EDT
Calcium Plus Vitamin D Supplements May Help Prevent Weight Gain In Postmenopausal Women
JAMA - Journal of the American Medical Association

Postmenopausal women who take calcium and vitamin D supplements may gain less weight than those who do not, although the overall effect is small, according to a report in the May 14 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. The benefit is greater in those who had not previously been getting the daily recommended amount of calcium.

10-May-2007 5:40 PM EDT
Grain Fiber and Magnesium Intake Associated With Lower Risk for Diabetes
JAMA - Journal of the American Medical Association

Higher dietary intake of fiber from grains and cereals and of magnesium may each be associated with a lower risk of type 2 diabetes, according to a report and meta-analysis in the May 14 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

10-May-2007 5:40 PM EDT
Testosterone May Help Men With Multiple Sclerosis
JAMA - Journal of the American Medical Association

A small pilot study suggests that testosterone treatment is safe, well tolerated and may reduce symptoms, slow brain degeneration and increase muscle mass in men with relapsing-remitting multiple sclerosis, the most common form of the disease, according to a report in the May issue of Archives of Neurology, one of the JAMA/Archives journals.

10-May-2007 5:45 PM EDT
Coenzyme Q10 Does Not Improve Parkinson’s Disease Symptoms
JAMA - Journal of the American Medical Association

Small doses of the antioxidant coenzyme Q10 appear to increase blood levels of this naturally occurring compound in patients with Parkinson's disease, but does not improve Parkinson's disease symptoms, according to an article posted online today that will appear in the July 2007 print issue of Archives of Neurology, one of the JAMA/Archives journals.

3-May-2007 4:05 PM EDT
Angioplasty Reduces Long-Term Cardiac Risk Among Heart Patients with 'Silent' Ischemia
JAMA - Journal of the American Medical Association

When compared with intensive drug therapy, percutaneous coronary intervention (PCI, angioplasty) was more beneficial in reducing the long-term risk of major cardiac events among heart attack survivors with "silent ischemia", according to a study in the May 9 issue of JAMA.

3-May-2007 4:10 PM EDT
Off-Label, Untested Use of Drug-Coated Stents Appears Widespread; Associated With Higher Rates of Complications
JAMA - Journal of the American Medical Association

The off-label and untested use of drug-coated stents in the treatment of coronary artery blockage is common in U.S. practice, and ischemic complication rates are higher among patients receiving drug-coated stents for off-label indications, according to two studies in the May 9 issue of JAMA.

3-May-2007 4:00 PM EDT
Hepatitis C Increases Risk of Non-Hodgkin Lymphoma
JAMA - Journal of the American Medical Association

Hepatitis C infection is associated with an increased risk of non-Hodgkin lymphoma (malignancy involving lymphatic tissue) of 20 percent to 30 percent, and a three-fold increase in the risk of another type of lymphoma, according to a study in the May 9 issue of JAMA.

3-May-2007 4:00 PM EDT
More than 4 Percent of U.S. Adults Estimated to Have Some Form of Bipolar Disorder
JAMA - Journal of the American Medical Association

Approximately 4.4 percent of U.S. adults may have some form of bipolar disorder during some point in their lifetime, including about 2.4 percent with a "sub-threshold" condition, according to an article in the May issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

3-May-2007 4:00 PM EDT
More Than 10 Percent of Adults Abuse or Become Dependent on Drugs During Their Lifetime
JAMA - Journal of the American Medical Association

Approximately 10.3 percent of U.S. adults appear to have problems with drug use or abuse during their lives, including 2.6 percent who become drug dependent at some point, according to a report in the May issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

3-May-2007 5:20 PM EDT
Traumatic Events, but Not Post-traumatic Stress Disorder, Common in Childhood
JAMA - Journal of the American Medical Association

Potentially traumatic events are common in children but do not typically result in post-traumatic stress symptoms or disorder, according to a report in the May issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

26-Apr-2007 6:30 PM EDT
Drug for Treatment of Heart Failure Does Not Improve Survival, Compared to More Widely-Used Medication
JAMA - Journal of the American Medical Association

The drug levosimendan did not improve survival for patients with decompensated heart failure when compared with a more widely-used treatment for this condition, dobutamine, according to a study in the May 2 issue of JAMA.

26-Apr-2007 6:40 PM EDT
Improvements in Therapies for Patients With Acute Coronary Syndrome
JAMA - Journal of the American Medical Association

Recent changes in the recommended treatments used for patients hospitalized for acute coronary syndromes, such as a heart attack, are associated with reductions in the rates of heart failure, stroke, heart attack and death, according to a study in the May 2 issue of JAMA.

26-Apr-2007 4:00 PM EDT
Molecular Marker May Help Identify Pancreatic Cancer, and Possibly Predict Survival Time
JAMA - Journal of the American Medical Association

Preliminary research suggests that the expression pattern of microRNA (a short RNA molecule) may be useful in differentiating between chronic pancreatitis and pancreatic cancer and may be able to distinguish long and short term survival time for patients with pancreatic cancer, according to an article in the May 2 issue of JAMA.

19-Apr-2007 5:15 PM EDT
New Data Supports Safety of Anti-Anginal Drug But Not Its Effectiveness
JAMA - Journal of the American Medical Association

The anti-anginal medication ranolazine was shown to be safe in regard to certain outcomes but did not reduce the risk of major cardiovascular events such as death, heart attack or recurrent ischemia following acute coronary syndromes, according to a study in the April 25 issue of JAMA.

19-Apr-2007 5:20 PM EDT
Increase in Serious Pneumococcal Infections Not Covered by Childhood Pneumococcal Vaccine
JAMA - Journal of the American Medical Association

Alaska Native children are experiencing increased rates of serious infections caused by strains of pneumococcal bacteria that are not covered by the current childhood pneumococcal vaccine, indicating the importance of ongoing surveillance of vaccine effectiveness, according to a study in the April 25 issue of JAMA.

19-Apr-2007 5:20 PM EDT
Common Genetic Variants Associated With Progression to Advanced Forms of Age-Related Macular Degeneration
JAMA - Journal of the American Medical Association

Variations of two common genes are associated with progression to more advanced forms of age-related macular degeneration, and factors such as smoking and being overweight greatly increase this risk, according to a study in the April 25 issue of JAMA.

19-Apr-2007 5:55 PM EDT
Neither Abortion Nor Miscarriage Associated With Breast Cancer Risk
JAMA - Journal of the American Medical Association

Neither induced abortion nor spontaneous abortion (miscarriage) appears to be associated with breast cancer risk in premenopausal women, according to a report in the April 23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

19-Apr-2007 6:00 PM EDT
Obesity May Be Associated With Disability in Workers, Elderly
JAMA - Journal of the American Medical Association

Obese individuals appear more likely to file workers' compensation claims for injuries on the job, according to a report in Archives of Internal Medicine. A second report in the same issue suggests that older Americans with a body mass index (BMI) of between 25 and 30"”considered to be overweight"”may have a higher risk of disability but a lower risk of death than those with BMI in the recommended range of 18.5 to 25.

19-Apr-2007 4:00 PM EDT
Symptoms of Depression Associated with Development of Diabetes in Older Adults
JAMA - Journal of the American Medical Association

Older adults who have had symptoms of depression"”whether those symptoms occurred once, increased or remained steady over a 10-year period"”may be more likely to develop diabetes than those without depressive symptoms, according to a report in the April 23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

19-Apr-2007 6:10 PM EDT
Migraines Associated With Increased Risk of Cardiovascular Disease in Men
JAMA - Journal of the American Medical Association

Men with migraine headaches may be at an increased risk for major cardiovascular disease and especially heart attacks, according to a report in the April 23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

12-Apr-2007 4:00 PM EDT
Anemia Treatment For Patients With Kidney Disease Can Differ by Dialysis Facility Type
JAMA - Journal of the American Medical Association

Large, for-profit dialysis facilities appear to administer higher than necessary amounts of a medication for treating anemia in patients with kidney disease, compared to nonprofit facilities, according to a study in the April 18 issue of JAMA.

12-Apr-2007 4:00 PM EDT
Benefits of Antidepressants Appear Greater Than Risks for Children, Teens
JAMA - Journal of the American Medical Association

A review of previous studies indicates that the benefits of antidepressants for children and teens with depression or anxiety disorders may outweigh their risks, and that the increased risk for suicidal thoughts and attempts from using these medications is not statistically significant, according to an article in the April 18 issue of JAMA.

5-Apr-2007 6:05 PM EDT
Study Fails to Verify Gene Variations as Risk Factors for Certain Cardiovascular Problems
JAMA - Journal of the American Medical Association

New research has failed to confirm findings from smaller studies that 85 gene variations are associated with an increased risk for acute coronary syndromes (ACS), which includes heart attack and a type of angina, according to a study in the April 11 issue of JAMA.

5-Apr-2007 6:10 PM EDT
Use of Hydrocortisone Reduces Incidence of Atrial Fibrillation After Cardiac Surgery
JAMA - Journal of the American Medical Association

Patients who receive corticosteroids after cardiac surgery have a significantly lower risk of atrial fibrillation in the days following the surgery, according to a study in the April 11 issue of JAMA.

5-Apr-2007 6:15 PM EDT
Use of Stem Cell Transplantation is Beneficial Treatment of Type 1 Diabetes
JAMA - Journal of the American Medical Association

A therapy that includes stem cell transplantation induced extended insulin independence in patients with type 1 diabetes mellitus, according to a preliminary study in the April 11 issue of JAMA.



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