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A multi-institutional study led by researchers at The University of Texas M. D. Anderson Cancer Center has found that using chemotherapy alone and delaying or avoiding cranial radiation altogether can be effective in treating pediatric patients with unresectable or progressive low-grade glioma. The study was presented Sunday at the 40th annual International Society of Pediatric Oncology Meeting in Berlin, Germany.

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The National Cancer Institute (NCI) has renewed The University of Texas M. D. Anderson Cancer Center's Cancer Center Support Grant, an essential step in extending the institution's elite status as a comprehensive cancer center.

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The University of Texas M. D. Anderson Cancer Center has received nearly $19 million in grants from Susan G. Komen for the Cure as part of that organization's new initiative to fast-track promising research to benefit breast cancer patients.

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In a first-of-its-kind finding, researchers at The University of Texas M. D. Anderson Cancer Center have discovered that exposure to the hepatitis B virus (HBV) may increase the risk of pancreatic cancer.

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Women with three or fewer involved lymph nodes appear to have low relapse rate after undergoing pre-operative chemotherapy.

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Counting the copies of a specific gene in cells gathered from a urine sample may provide a simple, noninvasive way to detect bladder cancer, a team led by researchers at The University of Texas M. D. Anderson Cancer Center reports in the Journal of the National Cancer Institute.

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Cancer patients who receive stereotactic radiosurgery (SRS) and whole brain radiation therapy (WBRT) for the treatment of metastatic brain tumors have more than twice the risk of developing learning and memory problems than those treated with SRS alone, according to new research from The University of Texas M. D. Anderson Cancer Center.

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The protein IKKalpha (IKKα) regulates the cell cycle of keratinocytes and plays a key role in keeping these specialized skin cells from becoming malignant, researchers at The University of Texas M. D. Anderson Cancer Center report in the Sept. 9 issue of Cancer Cell.

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Lung cancer risk prediction models are enhanced by taking into account risk factors by race and by measuring DNA repair capacity, according to research teams led by epidemiologists at The University of Texas M. D. Anderson Cancer Center in two complementary papers appearing in the September issue of Cancer Prevention Research.

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Black women are less likely than white women to receive radiation therapy after a lumpectomy, the standard of care for early stage breast cancer, according to a new study by researchers at The University of Texas M. D. Anderson Cancer Center.

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Researchers at The University of Texas M. D. Anderson Cancer Center have discovered that when treated with Herceptin prior to surgery, 50 percent of HER2 positive, breast cancer patients showed no signs of disease at the time of surgery. However, of those women who had residual disease, about one-third had tumors that converted from HER2 positive to HER 2 negative status "”possibly indicating a resistance to the targeted therapy.

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Women whose lives have been touched by the breast cancer experience of a friend or relative are more acutely attuned to their own risk for the disease and are taking action to protect themselves, according to a new national opinion poll by The University of Texas M. D. Anderson Cancer Center and Prevention magazine.

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Breast cancer patients and their physicians may make more informed, long-term treatment decisions using risk assessment strategies to help determine probability of recurrence, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reported in the Aug. 12 online issue of the Journal of the National Cancer Institute.

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New preclinical research shows that cannabinoid cell surface receptor CB1 plays a tumor-suppressing role in human colorectal cancer, scientists report in the Aug. 1 edition of the journal Cancer Research.

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An abundant chromosomal protein that binds to damaged DNA prevents cancer development by enhancing DNA repair, researchers at The University of Texas M. D. Anderson Cancer Center report online this week in the Proceedings of the National Academy of Sciences.

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Scientists from The University of Texas M. D. Anderson Cancer Center have found overexpression of tissue type transglutaminase (TG2) in ovarian cancer is associated with increased tumor cell growth and adhesion, resistance to chemotherapy and lower overall survival rates. When researchers targeted and silenced TG2 in animal models, cancer progression was reversed, suggesting the protein may also provide a novel therapeutic approach for late-stage ovarian cancer.

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The University of Texas M. D. Anderson Cancer Center today signed a sister institution agreement with the Sir Y.K. Pao Centre for Cancer and Hong Kong Cancer Institute at the Chinese University of Hong Kong (CUHK), formalizing existing collaborations between the two cancer centers based on their shared missions of scientific discovery, patient therapies, education and prevention.

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The University of Texas M. D. Anderson Cancer Center once again is the top hospital in the nation for cancer care, according to the U.S. News & World Report annual "America's Best Hospitals" survey.

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Thyroid cancer that has spread to distant sites has a poor prognosis, but an experimental drug that inhibits tumor blood vessel formation can slow disease progression in some patients, a research team led by investigators from The University of Texas M. D. Anderson Cancer Center reports in the July 3rd edition of The New England Journal of Medicine.

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Researchers at The University of Texas M. D. Anderson Cancer Center will advance two new therapeutic approaches for malignant brain tumors and develop biomarkers to guide treatment decisions under a major translational research grant from the National Cancer Institute.

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The University of Texas M. D. Anderson Cancer Center's Radiation Treatment Center in Bellaire has added partial-breast irradiation, a new approach to treating some breast cancer patients who are undergoing lumpectomies, to its complement of radiation therapy services.

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More people in the U.S. are living longer after a cancer diagnosis. For this increasing number of cancer survivors, living a better quality of life is just as important as living through the disease. Improving communication and acknowledging stress can enhance the quality of life of cancer survivors and those who support them.

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Metformin, the common first-line drug for type 2 diabetes, may be effective in increasing pathologic complete response rates in diabetic women with early stage breast cancer who took the drug during chemotherapy prior to having surgery, paving the way for further research of the drug as a potential cancer therapy, according to researchers at The University of Texas M. D. Anderson Cancer Center.

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A gene therapy invented at The University of Texas M. D. Anderson Cancer Center is the first to succeed in a U.S. phase III clinical trial for cancer, as announced today at the American Society of Gene Therapy annual meeting in Boston.

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Efforts to protect the tumor-suppressor p53 could just as easily shelter a mutant version of the protein, causing cancer cells to thrive and spread rather than die, according to research by scientists at The University of Texas M. D. Anderson Cancer Center reported in the current issue of the journal Genes and Development.

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A poster session presented today by The University of Texas M. D. Anderson Cancer Center at the Oncology Nurses Society 33rd Annual Congress, found that early nursing intervention and implementation of effective strategies can lead to a decrease in the incidence of lymphedema, better management of chronic lymphedema and improved quality of life in breast cancer patients.

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Researchers from The University of Texas M. D. Anderson Cancer Center have found a therapy that effectively kills human leukemia cells in mice using natural killer (NK) cells from umbilical cord blood.

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Researchers at The University of Texas M. D. Anderson Cancer Center have discovered a drug combination that kills leukemia cells by shutting down their energy source and hastening cell starvation.

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Gefitinib, the once-promising drug formerly approved as a second line treatment for lung cancer, also known as Iressa, enhanced the effectiveness of hormonal therapy for the treatment of specific types of metastatic breast cancer, according to a Phase II clinical trial led by researchers at The University of Texas M. D. Anderson Cancer Center.

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Celecoxib, the anti-inflammatory medication also known by the trade name Celebrex, has proven to be safe and reduces a specific proliferation measurement of precancerous lesions in the lung, according to a study from The University of Texas M. D. Anderson Cancer Center. This finding demonstrates the significance of COX-2 inhibition toward preventing lung cancer in individuals at higher risk of developing the disease.

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In an effort to better define and ultimately address fatigue more effectively, a qualitative study from The University of Texas M. D. Anderson Cancer Center has identified three primary themes - loss of strength or energy, major effects of fatigue and associated sensations - among patients being treated with standard radiation therapy.

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The Dan L. Duncan Family Foundation has given The University of Texas M. D. Anderson Cancer Center $35 million-the institution's largest gift to the cancer prevention program and its second-largest gift in its 67-year history. The funds will be used to establish the Dan Duncan Family Institute for Cancer Prevention and Risk Assessment.

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According to nurse-researchers at The University of Texas M. D. Anderson Cancer Center in Houston, participation among nurses in the institution's unique Professional Action Coordinating Teams (PACTs) has increased 50 percent in one year.

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Researchers from The University of Texas M. D. Anderson Cancer Center have found a possible approach to therapy that may make cancer cells more sensitive to attack by immune system cells while making the immune system cells more powerful.

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M. D. Anderson-led team's whole-organ genomic survey depicts journey from normal to malignant cell.

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A growth factor receptor found abundantly on the surface of cancer cells and long known to fuel cancer growth also protects tumor cells from starvation by a newly identified mechanism, researchers at The University of Texas M. D. Anderson Cancer Center report in the May 5 issue of Cancer Cell.

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Before leaving home for a day of outdoor activity, take appropriate precautions to ensure that your and your family's skin is well-protected. According to Susan Chon, M.D., assistant professor of dermatology at The University of Texas M. D. Anderson Cancer Center, the majority of all skin cancers are caused by the sun.

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F. O'Neil "Neil" Griffin Conference and Education Center Dedicated on South Campus

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The University of Texas M. D. Anderson Cancer Center today signed a sister institution agreement with the German Cancer Research Center (DKFZ), Germany's premier cancer center which is renowned particularly for excellence in basic cancer research. The mission-driven agreement formalizes long-standing academic relationships among faculty at both institutions.

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When administered before chemoradiation, the common anti-cancer drug cisplatin neither improved disease-free survival nor reduced the number of colostomies needed when compared to the standard treatment for patients with anal canal cancer, according to a study published in the April 23 issue of the Journal of the American Medical Association.

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According to researchers at The University of Texas M. D. Anderson Cancer Center, mammography, the gold-standard for breast cancer screening and early detection, has shown to significantly reduce the risk of being diagnosed with advanced stage breast cancer in women over the age of 80, an age group currently without clear guidelines for regular screenings.

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M. D. Anderson findings point to immune dysfunction as cause, explain age as risk factor.

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M.D. Anderson-led team connects dietary balance to common cancer pathways.

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Prevention of weight gain with a restricted calorie diet sharply reduced the development of pancreatic lesions that lead to cancer in preclinical research reported today by researchers from The University of Texas at Austin and The University of Texas M. D. Anderson Cancer Center at the American Association for Cancer Research annual meeting.

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Cells lining the mouth reflect the molecular damage that smoking does to the lining of the lungs, researchers at The University of Texas M. D. Anderson Cancer Center report today at the annual meeting of the American Association for Cancer Research.

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Simple Tips to Keep Skin Safe This Summer from The University of Texas M. D. Anderson Cancer Center.

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National Minority Cancer Awareness Week is April 20-26, and The University of Texas M. D. Anderson Cancer Center is encouraging people to learn about the growing disparity in cancer incidence and death rates that affect minority populations.

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A collaboration between a non-profit cancer center and a for-profit drug company allow for research to better understand and treat side effects of cancer treatment, such as pain and neuropathy.

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This story describes a variety of new clinical trials at M. D. Anderson for patients with Hodgkin's lymphoma, giving them a wider choice of battling their disease.

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To radiation, chemotherapy, surgery and biological therapies deployed to wage war on cancer, M. D. Anderson researchers have added a new approach "” diplomacy. A look at epigenetics.