Matthew Miller, MD, Daniel Rubinstein, MD, and Hussam Banna, MD, from the UNC School of Medicine joined forces to perform the first corneal neurotization procedure at UNC, a life-changing surgery for patients who have neurotrophic keratitis.
Children’s hospital care is now concentrated in fewer locations, because of a shift in children's care from general hospitals to higher volume children's specialty centers, and this has important implications for hospital planning and readiness, according to a new study led Michael Steiner, MD, MPH, of UNC Health.
UNC School of Medicine researchers led an international team of researchers to conduct the largest-ever meta-analyses of genome-wide association studies (GWAS) to investigate the genetic architecture of PPD.
A clinical study led by Edwin Kim, MD, at the UNC School of Medicine, showed how Peanut Sublingual Immunotherapy (Peanut SLIT) is safe and effective in children ranging from 1-to-4 years of age. Remission of peanut allergy was also possible after three months of stopping the treatment.
A groundbreaking study presented today by University of North Carolina (UNC) School of Medicine researchers at the XXIV FIGO World Congress of Gynecology and Obstetrics could revolutionize pregnancy care, especially in areas with limited resources.
Researchers in the UNC School of Medicine have developed an AI model that can predict whether or not cancerous tissue has been fully removed from the body during breast cancer surgery.
Led by scientists at UNC-Chapel Hill and UC-San Francisco, research reveals new non-coding genetic variants associated with Alzheimer’s disease functioning in microglia – brain cells already implicated in the progression of this often-fatal neurodegenerative condition.
Scientists revealed the intercellular choreography that governs protein regulation, including how unwanted proteins are tagged for degradation, an important player in human health and disease.
Ron Alterovitz, PhD, in the UNC Computer Science Department, and Jason Akulian, MD MPH, in the UNC School of Medicine, have shown that their steerable lung robot can autonomously maneuver the intricacies of the lung, while avoiding important lung structures.
An international study has revealed strong associations between oral health and survival among people diagnosed with head and neck cancer. Specifically, better oral health, as evidenced by the number of natural teeth and dental visits prior to the time of diagnosis, was associated with increased survival.
Scientists figuring out which of the 5,000-plus genetic variants associated with schizophrenia have an actual causal effect in the development of the condition. Some of genetic variants regulate or alter the expression of genes involved in the condition.
A phase 2 study, led by Thomas W. Ferkol, MD, at the UNC School of Medicine, demonstrates safety and efficacy of idrevloride with hypertonic saline for treatment of primary ciliary dyskinesia, a rare genetic disorder that can lead to permanent lung damage.
Over the years, dedicated sickle cell disease programs and research initiatives have greatly improved patient care and life expectancy. But, giving these patients the care they require still presents a number of challenges, including inadequate funding for sickle cell programs, lack of research, and limited access to healthcare.
Anxiety remains one of the most diagnosed clinical symptoms in adolescence and is a potent precursor to and exacerbator of substance use disorder. Through this NIH-funded study, UNC Chapel Hill researchers will examine the neural and physiological mechanisms associated with emergence of substance use in adolescence who experience anxiety.
The new observation, made by UNC School of Medicine’s Stephan Moll, MD, and Jacquelyn Baskin-Miller, MD, suggests that a life-threatening blood clotting disorder can be caused by an infection with adenovirus, one of the most common respiratory viruses in pediatric and adult patients.
UNC School of Medicine researchers Angela Wahl, PhD, Balfour Sartor MD, J. Victor Garcia, PhD, and colleagues created a germ-free mouse model to evaluate the role of the microbiome in the infection, replication, and pathogenesis of HIV and the Epstein-Barr virus, the virus that can cause mononucleosis and other serious diseases.
Researchers in UNC School of Medicine’s Department of Otolaryngology/Head and Neck Surgery and collaborators at Yale Cancer Center and ECOG-ACRIN Cancer Research Group have identified two subtypes of human papillomavirus positive head and neck cancers, giving them a better glimpse into why some patients respond better to treatment than others.
Hidradenitis suppurativa (HS) is a chronic inflammatory follicular disease which causes painful lumps to form under the skin. The lumps typically form in areas where skin rubs together – such as the armpits, groin, and under the breasts. HS can range in severity from occasional fluid-filled abscesses to widespread rope-like scarring, chronic pain, and increase of infection.
The Tobacco Prevention and Evaluation program (TPEP) in the UNC School of Medicine has been awarded a two-year, $887,431 contract from JUUL Settlement funds received by the NC Department of Health and Human Services to better understand electronic cigarette use among our youth and young adults.
Enzyme mutations have been of great interest to scientists who study cancer. Scientists in the Liu and Tan labs at UNC’s Lineberger Comprehensive Cancer Center have been studying mutations of enzyme recognition motifs in substrates, which may more faithfully reflect enzyme function with the potential to find new targets or directions for cancer treatment.
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