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Johns Hopkins researchers studying the genetic changes underlying some cancers and genetic disorders have shown how a single gene can play a role in two very different and distinct inherited disorders, a heart rhythm disturbance and a rare growth ailment.

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Johns Hopkins researchers have resolved a longstanding controversy by showing that allergy shots add little or no benefit to standard drug treatment for children with year-round moderate to severe asthma.

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In a government-supported study of more than 300 fatal and non-fatal bicycle accidents, Johns Hopkins researchers found that alcohol was a factor in at least a third of the deaths.

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Johns Hopkins Children's Center scientists have identified TWIST as the disease gene causing Saethre-Chotzen syndrome, one of the most common genetic conditions with craniosynostosis, the early closure of the cranial sutures. Their findings, which also include the mapping of TWIST in the human genome, appear in the January issue of Nature Genetics.

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Johns Hopkins scientists studying scleroderma may have identified the unique molecular footprints on the biochemical trail leading the immune system to attack its own tissues.