Credit: Courtesy Isaac Kohane, MD, PhD, Children's Hospital Boston
GENE EXPRESSION IN BRONCHOPULMONARY DYSPLASIA. The pattern of blue dots indicates that no individual gene was expressed significantly differently in infants who went on to develop bronchopulmonary dysplasia (BPD) as compared with those who didn't: the dots are as likely to fall above the horizontal line as below it. However, the genes in the chromatin remodeling pathway -- represented by yellow squares -- are significantly more likely to fall below the line, indicating that, as a group, they are "turned on" less often in infants who develop BPD.