Credit: Krzysztof Palczewski, Ph.D.
Four imaging techniques show significantly more retinal damage following light exposure in the eyes of untreated versus treated mice. Thinning of the layers of the retina is shown in top images. Autofluorescent spots (shown bottom left), indicating light damage, are plentiful in untreated animals and absent in treated ones. Two-photon microscopy (bottom right) shows enlargement of the photoreceptors in untreated mice compared with treated ones.