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Sanford Burnham Prebys Medical Discovery Institute welcomes new trustees Karen Haynes and Donald Kearns

Sanford Burnham Prebys Medical Discovery Institute today announced that Karen Haynes, Ph.D., president emerita at California State University San Marcos, and Donald Kearns, M.D., president emeritus at Rady Children’s Hospital-San Diego, have been...
24-Feb-2020 8:00 AM EST Add to Favorites

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A deep dive into cellular aging

Scientists at Sanford Burnham Prebys Medical Discovery Institute and Harvard University have discovered that mitochondria trigger senescence, the sleep-like state of aged cells, through communication with the cell’s nucleus—and identified an...
18-Feb-2020 5:10 PM EST Add to Favorites

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Prebiotics help mice fight melanoma by activating anti-tumor immunity

Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that two prebiotics, mucin and inulin, slowed the growth of melanoma in mice by boosting the immune system’s ability to fight cancer. The study, published today in Cell...
6-Feb-2020 4:35 PM EST Add to Favorites

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Why can’t Bertrand Might cry? Scientists offer an answer: missing water channels

Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that cells from children with NGLY1 deficiency—a rare disorder first described in 2012—lack sufficient water channel proteins called aquaporins. The discovery was...
13-Jan-2020 5:05 PM EST Add to Favorites

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Study reveals a new approach to enhancing response to immunotherapy in melanoma

Scientists at Sanford Burnham Prebys have identified a new way to boost the immune system’s ability to fight cancer. The study used a mouse model to identify the importance of the Siah2 protein in the control of immune cells called T regulatory...
3-Jan-2020 11:40 AM EST Add to Favorites

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The secret to a long life? For worms, a cellular recycling protein is key

Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that worms live longer lives if they produce excess levels of a protein, p62, which recognizes toxic cell proteins that are tagged for destruction. The discovery, published...
10-Dec-2019 4:05 PM EST Add to Favorites

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One-two punch drug combination offers hope for pancreatic cancer therapy

Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified a combination of two anti-cancer compounds that shrank pancreatic tumors in mice—supporting the immediate evaluation of the drugs in a clinical trial. U.S. Food and...
18-Nov-2019 11:00 AM EST Add to Favorites

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Sanford Burnham Prebys awarded $3.58 million NIH grant to advance potential treatment for opioid-use disorders

The National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), awarded a $3.58 million grant to Sanford Burnham Prebys scientist Anthony Pinkerton, Ph.D., to advance a potential treatment for opioid-use disorders,...
21-Oct-2019 1:35 PM EDT Add to Favorites


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Sanford Burnham Prebys is a preeminent, independent biomedical research institute dedicated to understanding human biology and disease and advancing scientific discoveries to profoundly impact human health. For over 40 years, our research has produced breakthroughs in cancer, neuroscience, immunology and children’s diseases, and is anchored by our NCI-designated cancer center and advanced drug discovery capabilities. For more information, visit us at SBPdiscovery.org or on Facebook at facebook.com/SBPdiscovery and on Twitter @SBPdiscovery.

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