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From tobacco to alcohol to opioids, Sanford Burnham Prebys researchers are pursuing novel leads and promising therapies to treat addiction

Tens of millions of Americans are addicted to illicit drugs, alcohol, tobacco and other substances including opioids, with both immediate and long-term harm to not just themselves, but also family, friends and society.
16-Nov-2023 3:05 PM EST Add to Favorites

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“DNA loops” in pediatric brain tumors double relapse risk

A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA—loops of DNA found outside of regular chromosomes—are twice as likely to relapse and three times as likely to die...
14-Nov-2023 9:05 AM EST Add to Favorites

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Inhibiting an enzyme associated with aging could help damaged nerves regrow and restore strength

Scientists at Stanford University School of Medicine and Sanford Burnham Prebys have demonstrated a new way to accelerate recovery from peripheral nerve injury by targeting an enzyme that was thought to be responsible for muscle wasting with aging.
11-Oct-2023 7:05 PM EDT Add to Favorites

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Copycat nutrient leaves pancreatic tumors starving

A study led by scientists at Sanford Burnham Prebys suggests an entirely new approach to treat pancreatic cancer. The research shows that feeding tumors a copycat of an important nutrient starves them of the fuel they need to survive and grow.
7-Oct-2023 2:05 PM EDT Add to Favorites

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New grant funds study of very aggressive childhood brain cancers driven by circular pieces of DNA

Lukas Chavez, Ph.D., has received $3.2 million from the National Institutes of Health to study how unique DNA circles found in cancer cells drive deadly pediatric brain tumors. The research aims to expose how the circular pieces of DNA contribute to...
14-Sep-2023 8:05 AM EDT Add to Favorites

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US Department of Defense backs Cosimo Commisso’s pancreatic cancer research

Cosimo Commisso, Ph.D., has received a grant from the Department of Defense for $1 million to advance the research of a small molecule that kills pancreatic cancer cells by disrupting their pH equilibrium.
7-Sep-2023 5:00 AM EDT Add to Favorites

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Timothy Huang awarded $2.6M to solve Alzheimer’s disease puzzle

With the help of a new grant from the National Institutes of Health for more than $2.6 million, Assistant Professor Timothy Huang, Ph.D., will continue his research on the role of the brain’s immune cells on the risk of developing Alzheimer’s...
6-Sep-2023 5:00 AM EDT Add to Favorites

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Sanford Burnham Prebys Cancer Center earns merit extension from NCI

Sanford Burnham Prebys’ Cancer Center has received a rare and prestigious Merit Extension Award from the National Cancer Institute (NCI), recognizing and rewarding its earlier accomplishments as well as current research plans. The award extends...
9-Aug-2023 4:05 PM EDT Add to Favorites

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Sanford Burnham Prebys is a preeminent, independent biomedical research institute dedicated to understanding human biology and disease and advancing scientific discoveries to profoundly impact human health. For over 40 years, our research has produced breakthroughs in cancer, neuroscience, immunology and children’s diseases, and is anchored by our NCI-designated cancer center and advanced drug discovery capabilities. For more information, visit us at SBPdiscovery.org or on Facebook at facebook.com/SBPdiscovery and on Twitter @SBPdiscovery.


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The “Eph” system may pave the way for novel cancer therapies

Elena Pasquale’s new review in Nature Reviews Cancer surveys the large body of data regarding Eph signaling ...
27 Nov 2023

Sanford Burnham Prebys’ Shadow Day supports diversity and inclusion in STEM education

Creating an inclusive environment in STEM is crucial for ensuring a broad range of perspectives and ideas, ult...
20 Nov 2023

Photo Gallery: Fishman Fund awards honors future research leaders

The La Jolla-based Sanford Burnham Prebys research institute celebrated its 2023 Fishman Fund Awards on Sept. ...
31 Dec 1969

Randal J. Kaufman among the world’s most influential scientists

Over the last decade, the publications of Randal J. Kaufman are among the top 1% in the world by number of cit...
15 Nov 2023

“DNA loops” in pediatric brain tumors double relapse risk

Unique DNA loops found outside regular chromosomes are linked to poor clinical outcomes in aggressive childhoo...
31 Dec 1969

Hudson Freeze joins experts to discuss testing to help CAD-affected children

Hudson Freeze joined an international panel of genetics experts on CAD deficiency: Beyond the genetics—a pod...
10 Nov 2023

From tobacco to alcohol to opioids, Sanford Burnham Prebys researchers are pursuing novel leads and promising therapies to treat addiction

Addiction is perhaps the most and least visible of public health crises in the United States. Tens of millions...
31 Dec 1969

How a Sugar Could Be a Potential Secondary Treatment for Cancer

A natural sugar called mannose is a type of hexose that is abundant in many different types of fruits. Recent ...
31 Dec 1969

A two-for-one approach to boost melanoma immunotherapy

New research from Sanford Burnham Prebys has helped explain how melanoma evades the immune system and may guid...
31 Dec 1969

Academia’s postdoc system is teetering, imperiling efforts to diversify life sciences

Fr young life scientists hoping to land a prestigious faculty job in academia, postdoctoral research is practi...
31 Dec 1969



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