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Enlarged Genotype-Phenotype Correlation for a Three-Base Pair Deletion in Neurofibromatosis Type 1

For people with the genetic disorder neurofibromatosis type 1, a three-base pair deletion in the NF1 gene has a mild phenotype, but the mutation causes complications that include non-optic brain tumors, mostly low-grade and asymptomatic, as well as...
17-Sep-2018 5:05 PM EDT Add to Favorites


Researchers Testing Innovative Childhood Obesity Intervention

UAB researchers will implement a new home-intervention model to teach mothers and children to form healthy habits right in the comfort of their homes.
17-Sep-2018 11:05 AM EDT Add to Favorites


Immune Response Mechanism Described for Fate Determination of T Cells

In a paper published in the journal Science, researchers have detailed a mechanism that sets the stage for the fate decision that gives rise to two major subsets of effector cells: T follicular helper cells and non-T follicular helper cells, known...
13-Sep-2018 3:05 PM EDT Add to Favorites


A “reset” of regulatory T-cells reverses chronic heart failure in mouse model

In mouse experiments, scientists have shown a way to hit an immunological “reset button” that ends inappropriately sustained inflammation. This reset reverses the pathologic enlargement and pumping failure of the heart, and it suggests a...
10-Sep-2018 10:05 AM EDT Add to Favorites


Novel Epigenetic Control Mechanism Found for Critical Brain Proteins in Memory Strengthening

Researchers have found a mechanism that links epigenetic changes to translational control during fear memory reconsolidation — several particular epigenetic changes in the hippocampus of the rat brain control downstream regulation of translation...
6-Sep-2018 4:30 PM EDT Add to Favorites


Clearing a Xenotransplantation Hurdle: Detecting Infectious Agents in Pigs

Researchers have developed and tested 30 quantitative assays for pig infectious agents. The assays had sensitivities similar to lab assays for viral loads in human patients. After validation, they also used the assays on nine sows and 22 piglets...
29-Aug-2018 1:05 PM EDT Add to Favorites

New Breathing Tube Used During Cardiac Arrest Could Save Thousands

A study comparing two breathing tubes used by paramedics during out-of-hospital cardiac arrest shows that the King laryngeal tube was superior to the more commonly used endotracheal tube, according to findings of the Pragmatic Airway Resuscitation...
28-Aug-2018 11:05 AM EDT Add to Favorites


What Parents Need to Know to Keep Their Children’s Eyes Safe and Healthy

UAB eye physicians say it is never too early to start caring for your child’s ocular health.
28-Aug-2018 9:05 AM EDT Add to Favorites

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Known for its innovative and interdisciplinary approach to education at both the graduate and undergraduate levels, the University of Alabama at Birmingham is an internationally renowned research university and academic medical center, as well as Alabama’s largest employer, with some 23,000 employees, and has an annual economic impact exceeding $7 billion on the state. The pillars of UAB’s mission include education, research, innovation and economic development, community engagement and patient care. Learn more at


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