Formerly known as nonalcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis (MASH) is an inflammatory disease characterized by liver scarring or fibrosis that progressively impairs liver function.
It is a major risk factor...
22-Aug-2024 3:05 PM EDT
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Scientists at Sanford Burnham Prebys and the La Jolla Institute for Immunology have revealed a new secret regarding senescence, a cellular state similar to sleep that is more likely to affect aged cells.
22-Aug-2024 1:05 PM EDT
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Scientists at Sanford Burnham Prebys and Salk Institute for Biological Studies have uncovered a new role for a protein known for its role in the brain helping control feelings of hunger or satiety, as well as in the liver to aid the body in...
2-Aug-2024 1:05 PM EDT
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Ze’ev Ronai, PhD, is stepping down as director of the National Cancer Institute-designated cancer center at Sanford Burnham Prebys, effective August 1. Cosimo Commisso, PhD, deputy director of the cancer center, will serve as interim head while a...
30-Jul-2024 1:05 PM EDT
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Scientists at Sanford Burnham Prebys, University of California San Diego and their international collaborators have reported that more types of lung cells can be infected by SARS-CoV-2 than previously thought, including those without known viral...
23-Jul-2024 2:05 PM EDT
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Nuclear pore complexes (NPCs) are channels composed of multiple proteins that ferry molecules in and out of the nucleus, regulating many critical cellular functions, such as gene expression, chromatin organization and RNA processes that influence...
5-Jun-2024 5:05 PM EDT
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Researchers at Sanford Burnham Prebys, with collaborators, illuminate how the fibrotic tumor microenvironment creates an inhospitable milieu for anti-tumor immunity, not just by creating a physical barrier but through metabolic changes that suppress...
4-Jun-2024 3:05 PM EDT
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Brooke Emerling, Ph.D., co-director of, and associate professor in, the Cancer Metabolism and Microenvironment Program at Sanford Burnham Prebys, is contributing to a revival of interest in an underappreciated set of enzymes called...
28-May-2024 1:00 PM EDT
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As a new assistant professor at Sanford Burnham Prebys faculty, Sun seeks to better understand the genetic and epigenetic underpinnings of cancers, using genome editing technologies, animal and patient-derived models, and other tools to develop more...
13-Mar-2024 9:05 AM EDT
Sanjeev S. Ranade, Ph.D., who joined the faculty of Sanford Burnham Prebys this month as an assistant professor in the Development, Aging and Regeneration program, studies how proteins called transcription factors (TFs) specifically control the...
22-Jan-2024 6:00 AM EST
Kelly Kersten, Ph.D., who joined Sanford Burnham Prebys this month as an assistant professor in the Cancer Metabolism and Microenvironment program, studies the interactions between immune cells and their microenvironment to better understand how...
17-Jan-2024 2:05 PM EST
Shengjie Feng, Ph.D. is an expert in cryo-electron microscopy, a Nobel Prize-winning imaging technology capable of creating stop-action movies of proteins and other biomolecules jostling and connecting with each other while mitochondria and other...
16-Jan-2024 12:05 PM EST
2-Oct-2017 8:00 AM EDT
19-Oct-2016 12:05 PM EDT
Sanford Burnham Prebys is an independent biomedical research institute dedicated to understanding human biology and disease and advancing scientific discoveries to improve human health. For over 40 years, our research has produced breakthroughs in cancer, neuroscience, immunology and children’s diseases, and is anchored by our NCI-designated cancer center and advanced drug discovery capabilities. For more information, visit us at SBPdiscovery.org or on Facebook at facebook.com/SBPdiscovery and on Twitter @SBPdiscovery.
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