Newswise — The following are late-breaking abstracts to be presented at the International Conference from May 14-19, 2010. Please click on the links below to view the associated abstract. Please observe embargo times that follow the titles.

Airway Basal Cells of Healthy Smokers and Human Lung Adenocarcinomas Share a Common Embryonic Stem Cell-like Transcriptional Program (embargoed until 8:15am CDT, May 19th, 2010) http://bit.ly/bQCX6j

Airway regeneration is delayed by prior depletion of bone marrow Clara cell secretory protein-expressing cells (embargoed until 1:30pm CDT, May 18th, 2010) http://bit.ly/aJJFRT

Involvement of Autophagy in Cigarette Smoking Extractinduced Cellular Senescence in Human Bronchial Epithelial Cells (embargoed until 8:15am CDT, May 18th, 2010) http://bit.ly/bz3WFF

Breastfeeding, aeroallergen sensitization and environmental exposures during infancy are determinants of childhood allergic rhinitis at age three (embargoed until 8:15am CDT, May 16th, 2010) http://bit.ly/9cUrkq

Loss of caveolin-1 expression leads to decreased calcium flux in freshly isolated airway smooth muscle cells (embargoed until 1:30pm CDT, May 18th, 2010) http://bit.ly/cIq0Kv

Dabigatran etexilate, an oral direct thrombin inhibitor, represses fibrotic changes in a murine model of pulmonary fibrosis (embargoed until 8:15am CDT, May 18th, 2010) http://bit.ly/cppe5R

Global DNA Methylation Analysis of Bronchial Epithelial Cells from Patients with Asthma, COPD With and Without Lung Cancer (embargoed until 8:15am CDT, May 18th, 2010) http://bit.ly/bF4IGL

Real-time dynamic CO2 administration: a novel treatment strategy for periodic breathing (embargoed until 8:15am CDT, May 18th, 2010) http://bit.ly/9TIQhW

Non-invasive evaluation of the effects of endothelin receptor antagonists on pulmonary blood flow in patients with pulmonary arterial hypertension at rest and under exercise (embargoed until 8:15am CDT, May 18th, 2010) http://bit.ly/cpq9OA

Notch 3 receptor is localized and activated from an intracellular compartment in embryonic lung vascular smooth muscle cells (embargoed until 8:15am CDT, May 19th, 2010) http://bit.ly/bTRWvY

The Effect of Exercise Intensity on Airway and Systemic Inflammation in Patients with COPD (embargoed until 1:30pm CDT, May 18th, 2010) http://bit.ly/dAUwku

Risk factors for post fiberoptic-bronchoscopy fever in immunocompetent children with recurrent pneumonia (embargoed until 1:30pm CDT, May 17th, 2010) http://bit.ly/dnKTUS

GENOME-WIDE ANALYSIS OF TRANSLATIONALREGULATED GEGE in Hypoxic Alveolar Epithelial Cells (embargoed until 8:15am CDT, May 16th, 2010) http://bit.ly/cvZcM9

Feasibility of Hypoglossal Nerve Stimulation Therapy to Treat Obstructive Sleep Apnea (embargoed until 8:15am CDT, May 17th, 2010) http://bit.ly/bj6eyv

TLR3 Signaling Is Required for Human Rhinovirus (HRV)-Induced Airways Neutrophilic Inflammation and Hyperresponsiveness But Not Viral Clearance in Experimentally-Infected Mice (embargoed until 8:15am CDT, May 18th, 2010) http://bit.ly/bVrJK8

Insulin-Like Growth Factor-I Modulates Bcl-2 Expression in Hyperplastic Mucous Cells (embargoed until 8:15am CDT, May 19th, 2010) http://bit.ly/arbz6e

Fibrotic Nanofiber Scaffolds Mimic In Vivo Lung Microenvironment in Pulmonary Fibrosis (embargoed until 1:30pm CDT, May 17th, 2010) http://bit.ly/ckzlWv

Asthma and Migration: Unmasking Asthma Potential. The International Study of Asthma and Allergy in Childhood (ISAAC) Phase Three (embargoed until 8:15am CDT, May 16th, 2010) http://bit.ly/c1U0mf

Homeostatic Role for Nuclear Factor-KappaB in the Lung (embargoed until 8:15am CDT, May 18th, 2010) http://bit.ly/crp2DP

Evaluation of Lung Clearance Index in Children with Cystic Fibrosis Compared to Canadian Controls (embargoed until 1:30pm CDT, May 17th, 2010) http://bit.ly/anJn7N

Mesenchymal Stem Cells in OVA-Sensitized and -Challenged Mice Produce Immunomodulatory Cytokines (embargoed until 8:15am CDT, May 18th, 2010) http://bit.ly/bZ6W0W

Neural crest cell origin and signals for intrinsic neurogenesis in the mammalian respiratory tract (embargoed until 8:15am CDT, May 16th, 2010) http://bit.ly/bSC9T4

SCH527123, a Novel Treatment Option for Severe Neutrophilic Asthma (embargoed until 8:15am CDT, May 17th, 2010) http://bit.ly/brETK2

Efficacy and Safety of Omalizumab in Patients With Moderate-to-Severe Persistent Asthma Poorly Controlled on High-Dose Inhaled Corticosteroids and Long-Acting Beta- Agonists—Results of a Phase IIIb Randomized Controlled Trial (embargoed until 1:30pm CDT, May 18th, 2010) http://bit.ly/cXsi8D

Health benefits from large scale ozone reduction in the United States (embargoed until 8:15am CDT, May 17th, 2010) http://bit.ly/c1Jiai

Integrating Palliative and Critical Care: Results of a Cluster Randomized Trial (embargoed until 1:30pm CDT, May 19th, 2010) http://bit.ly/9trWW7

Parent-Initiated Prednisolone for Acute Asthma in School Aged Children: A Randomised Clinical Trial (embargoed until 8:15am CDT, May 17th, 2010) http://bit.ly/cRCDpW

Crucial role for Protein kinase C alpha and arginase activation in the induction of pulmonary endothelial hyperpermeability by pneumolysin (embargoed until 8:15am CDT, May 17th, 2010) http://bit.ly/amfpW4

Quercetin Inhibits rhinovirus replication and subsequent chemokine response in Airway Epithelial Cells (embargoed until 8:15am CDT, May 19th, 2010) http://bit.ly/biacjD

Riociguat for Chronic Thromboembolic Pulmonary Hypertension and Pulmonary Arterial Hypertension: First Long-term Extension Data from a Phase II Study (embargoed until 8:15am CDT, May 17th, 2010) http://bit.ly/b94i2e

A Genome-wide Admixture Scan for Ancestry-linked Genes Predisposing to Sarcoidosis in African Americans (embargoed until 8:15am CDT, May 19th, 2010) http://bit.ly/9tQfHJ

Hypoxia-Induced Changes in the Murine Pulmonary Circulation are Attenuated by Treatment with sRAGE (embargoed until 8:15am CDT, May 19th, 2010) http://bit.ly/d642jt

The Role of IL-17A & Panton-Valentine-Leukocidin in the Pathogenesis of Staphylococcus aureus-Induced Skin Infection (embargoed until 8:15am CDT, May 16th, 2010) http://bit.ly/dp3wzm

Staphylococcal Activation Of EGFR Facilitates Invasion Across The Pulmonary Mucosal Barrier (embargoed until 8:15am CDT, May 18th, 2010) http://bit.ly/dgxpYR

Talactoferrin alfa reduces mortality in severe sepsis: Results of a Phase 2 randomized, placebo-controlled, double-blind study (embargoed until 8:15am CDT, May 17th, 2010) http://bit.ly/bnBzdV

Traditional and high tidal volumes are associated with prolonged mechanical ventilation and organ failure after cardiac surgery (embargoed until 8:15am CDT, May 17th, 2010) http://bit.ly/dATwqx

The Role of TLR signaling in the development of emphysema in ApoE-deficient mice (embargoed until 8:15am CDT, May 18th, 2010) http://bit.ly/bHMAtq

Tumor-Suppressor Protein p53 binds to RSV RNA and Increases RSV Replication by Enhancement of Viral Transcriptional (embargoed until 8:15am CDT, May 18th, 2010) http://bit.ly/caB6xO

Higher toxic potential of 2-stroke scooter exhaust emissions compared to 4-stroke scooter and diesel car emissions (embargoed until 8:15am CDT, May 18th, 2010) http://bit.ly/cSKO4X

Effect of Vitamin E and Selenium on Incidence of Physician-Diagnosed COPD: The Selenium and Vitamin E Cancer Prevention Trial (SELECT) (embargoed until 8:15am CDT, May 17th, 2010) http://bit.ly/ctEOLl

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