Precision medicine helps identify “at-risk rapid decliners” in early-stage kidney disease
Michigan Medicine - University of MichiganA novel therapeutic may halt rapid kidney function in some type 1 diabetic kidney disease patients.
A novel therapeutic may halt rapid kidney function in some type 1 diabetic kidney disease patients.
At one center, the number of hospital admissions among adolescents with eating disorders more than doubled during the first 12 months of the COVID-19 pandemic.
Nearly a quarter of parents have suspected their child might be delayed in their development, a new national poll finds – but they may not always share these concerns with a doctor.
University of Michigan Rogel Cancer Center names its first associate director for diversity, equity, inclusion and justice
A new blood test could signal whether treatment for metastatic HPV-positive throat cancer is working months earlier than standard imaging scans, allowing doctors to try alternatives sooner, initial results show.
Activity of the polycomb repressive complex 1 is essential for the development and maintenance of leukemic cells; disrupting it presents a new potential therapeutic approach.
In a new study, a team of researchers uncovered new mechanisms underlying an important type of resistance to modern prostate cancer drugs called lineage plasticity, where castration-resistant prostate cancers undergo a deadly identity switch. They also outline a promising path to overcoming this form of resistance: BET bromodomain inhibitors.
A decade-long study of distal radius fracture in older adults revealed that personalized medicine catering to a patient’s individual needs and environment, not age or X-rays, should guide treatment options. The federally funded study is the most collaborative, intense effort to try and answer a 200-year puzzle about how to treat one of the most common fractures in older adults.
Data sharing among 40 Michigan hospitals about the care and outcomes for thousands of inpatients with COVID-19 has led to reduced variation and findings that could inform care anywhere, including approaches for preventing blood clots and reducing overuse of antibiotics, as well as a risk prediction tool.
Nearly one in three Americans between the ages of 50 and 80 put off an in-person appointment for medical care in 2020 because they were worried about exposure to the novel coronavirus, new national poll data show.
When delivering moms require caesarians or their newborns need neonatal care, some families may spend as much as $10,000 out-of-pocket, according to a new Michigan Medicine-led study.
People with the rare autoimmune disease scleroderma, who likely experience more serious isolation during a global pandemic, saw their anxiety and depression improve after receiving online mental health intervention through an international study. Researchers say the support program could be extended to many vulnerable patient populations moving forward.
Researchers at Michigan Medicine found people with cerebral palsy have fragile bones that present high fracture risk, but at different times across the lifespan compared to the general population. The results helped them develop new sex-specific critical periods of bone health for this population.
Surgeons can ease their patients’ pain from common operations without prescribing opioids, and avoid the possibility of starting someone on a path to long-term use, a pair of new studies suggests.
Smokers needed their blocked arteries fixed nearly a decade earlier than non-smokers, and patients with obesity underwent these procedures four years earlier than non-obese patients, according to a new study from across Michigan.
As many older adults get back to normal life across the United States thanks to high rates of vaccination and lower COVID-19 activity, a new poll suggests many should watch their alcohol intake.
The approval of a new Alzheimer's disease drug is getting a lot of attention, but a recent scientific review of the evidence about dementia prevention shows an important role for primary care providers and patients to modify risk factors and protect brain health over the long term.
By sequencing the RNA of individual cells within multiple benign and cancerous kidney tumors, researchers from the University of Michigan Rogel Cancer Center have identified the cells from which different subtypes originate, the pathways involved and how the tumor microenvironment impacts cancer development and response to treatment.
In a subset of patients with partial lipodystrophy and/or NASH, the hormone leptin can be leveraged as a therapeutic agent to move fat out of the liver.
Prizes, lotteries, discounts and freebies for COVID-19 vaccination may help overcome vaccine hesitancy and reward the vaccinated too, but it's important to learn from this moment to inform other preventive health care, an expert says.
An effort by the Michigan Radiation Oncology Quality Consortium reduced unnecessary radiation therapy procedures, and saved the time and resources of patients and families.
The COVID-19 shutdown initially seemed to hit pause on pregnancy and birth rates, new research from one major hospital system suggests, but that trend is quickly reversing.
Americans who get seriously ill from COVID-19 in 2021 might have to pay thousands of dollars in bills from their hospitals, doctors and ambulance companies as insurance companies allow waivers for out-of-pocket costs to expire, a new study suggests.
Older adults with cerebral palsy are more likely to experience debilitating pains of musculoskeletal conditions, but researchers found they receive significantly less physical therapy for those ailments. The lead author says the results, while staggering, support their hypothesis that people with CP receive inequitable health care.
The protein ApoE has known roles in cardiovascular disease and Alzheimer’s — new research implicates it in pancreatic cancer.
While some studies suggest female patients treated by female physicians have better outcomes, there does not appear to be a relationship between operator and patient gender and outcome in patients undergoing coronary angioplasty or stenting.
Much of the conversation around COVID-19 focuses on death and survival. But 45% of patients hospitalized for the virus at Michigan Medicine during the pandemic's first wave experienced significant functional decline. Nearly 20% were discharged to a location other than their home. Researchers say this information highlights the true impact of COVID-19.
Continuing antiseizure treatment after a baby's neonatal seizures stop may not be necessary.
Nearly half a billion people have diabetes, but only 1 in 10 of those in low- and middle-income countries are getting the kind of care that could make their lives healthier, longer and more productive, according to a new global study of data. Many don’t even know they have the condition.
Now that a key policy regarding prescription of a medication for opioid use disorder has been changed, experts reflect on the remaining challenges standing in the way of more people getting effective medication-assisted treatment, and discuss efforts to overcome those barriers.
A study of more than 3 million insured U.S. adult patients under 65 found that nearly 3% take immunosuppressive drugs that may elevate risk for severe COVID-19 symptoms and hospitalization if they became infected. There is growing evidence that immunosuppressive drugs may also reduce the COVID vaccine's efficacy.
In the largest U.S. study of venom allergy and mastocytosis prevalence, Michigan Medicine researchers found that people with venom allergy are nearly 10 times more likely to suffer the bone marrow disorder that causes higher risk of fatal reactions. They also found that elevated levels of tryptase, a chemical secreted by allergy cells, may predict if a person is at higher risk for reaction to immunotherapy.
U-M researchers have discovered the first immune stimulating long noncoding RNA Involved in the body's response to cancer, suggesting potential approaches to improve immunotherapy treatment.
Before undergoing surgery, patients often go through a number of tests. In fact, about half of patients who had one of three common surgical procedures done in Michigan between 2015 and the midway point of 2019 received at least one routine test beforehand.
A quick guide to navigating life now that the CDC and many states have said that fully vaccinated people do not need to wear masks in many situations.
While some parents still have reservations about using telemedicine for their kids, the majority were satisfied with the experience, a new national poll suggests.
A quick guide to the most-valuable preventive care that adults need to get scheduled, to catch up on what they may have missed during the height of the pandemic, and to address issues that the pandemic might have worsened.
Researchers have developed first-in-class small-molecule inhibitors against a key leukemia protein, ASH1L.
If left untreated, gout can cause severe disability. But unlike rheumatoid arthritis, there are only a handful of ways to treat it. Researchers say a combination of two existing drugs disrupts antibody production and doubles treatment efficacy.
Programs that provide ongoing support to patients with painful conditions and complex medication regimens may also help them avoid using potentially risky opioid pain medications, or reduce the amount they use, a new study finds.
Twenty dollars a month might not seem like a lot to pay for health insurance. But for people getting by on $15,000 a year, it’s enough to make some drop their coverage – especially if they’re healthy. That could keep them from getting preventive or timely care, and could leave their insurance company with a sicker pool of patients than before.
Nearly one in five older adults say their mental health has gotten worse since the pandemic began in March 2020, and an equal percentage say their sleep has suffered in that time too. More than 1 in 4 say they’re more anxious or worried than before the COVID-19 era, according to a new poll of people age 50 to 80.
A new study finds Black patients are more likely to die after their heart bypass surgery if they’re at a hospital where some care teams see mostly white patients and others see mostly Black patients. On the other hand, mortality rates are comparable between Black and white patients after heart bypass surgery when the teams of health care providers at their hospitals all care for patients of all races.
When they go to the dentist, patients might not think that the pain prescription they receive could put them or their family at risk of an opioid overdose. But a new study shows that overdose rates were two and a half times higher among patients who filled a prescription for an opioid medication after a dental procedure.
Just 16% of men 18 to 21 years old have received at least one dose of the HPV vaccine at any age. Yet oropharyngeal cancer, which occurs in the throat, tonsils, and back of the tongue, is now the leading cancer caused by HPV — and 80% of those diagnosed with it are men.
COVID-19 vaccination has become a lightning rod for controversy over “vaccine passports” and claims of violations of medical privacy or individual rights. But as two experts explain, there's a long history of efforts to protect the health of others by requiring individuals to provide proof of vaccination or of a past infection, or seek a medical or religious exception.
Newly published analyses of data from polls of teens and young adults show the importance of framing pandemic-related messaging in terms of their role in protecting others from COVID-19.
Postponing procedures during the pandemic sparked anxiety and fear among patients, with many concerned about dying of their conditions before getting surgery.