Physician-scientists at Beth Israel Deaconess Medical Center reported that a common type of N95 respirator reprocessed with VHP maintained its function and effectiveness through 25 cycles of re-use.
In a pair of papers and a guest editorial published in Dimensions of Critical Care Nursing, nurse-scientists share their experiences nearly doubling the hospital’s intensive care unit capacity; identifying, training and redeploying staff; and developing and implementing a proning team to manage patients with acute respiratory distress syndrome during the first COVID-19 surge.
Researchers at Beth Israel Deaconess Medical Center (BIDMC) conducted a head-to-head test of the second-generation vaccine CV2CoV compared with CVnCoV. The scientists assessed the vaccines’ ability to provoke an immune response as well as their protective efficacy against COVID-19 in non-human primates.
A new study suggests that because of improvements in stent technology and changes in the types of patients receiving stents, the risks of DAPT may now outweigh the benefits for the average patient.
In a paper published in the New England Journal of Medicine, a team of experts at Beth Israel Deaconess Medical Center compared immune responses induced by the three COVID-19 vaccines over an eight-month follow-up period.
Researcher-physicians at Beth Israel Deaconess Medical Center used a novel, highly-sensitive test to measure the amount of toxin produced by C. difficile in the stool of patients with suspected infections.
In the first randomized trial examining the role of a deep-learning based computer-aided detection system during colonoscopy in the U.S., researchers reported a relative reduction of the miss rate by nearly a third when computer-aided detection was used in conjunction with standard-of-care colonoscopy.
Researchers uncovered the precise hypothalamic neurons that regulate the drive to engage in mating behaviors in mice. The study sets the stage for developing a targeted therapy to offset the sexual side effects linked to antidepressants that can discourage patients from treating mental illnesses.
Researchers systematically reviewed federally funded cardiovascular disease trials run between 2000 and 2019 to determine whether various recruitment strategies impacted the number of Black participants enrolled.
A team led by Dan H. Barouch, MD, PhD, has been awarded $4.9 million in annual funding over the next five years to find a cure for HIV. Barouch was one of ten primary investigators to receive a 2021 National Institutes of Health (NIH) Martin Delaney Collaboratories for HIV Cure Research award, which aims to expedite human immunodeficiency virus (HIV) cure research by bringing together research partners in academia, government, the private sector and the community; coordinating complex research studies, and mentoring the next generation of HIV cure researchers.
Researchers conducted the largest and longest observational study to date, using multiple body weight measurements among a racially and ethnically diverse population of gender diverse individuals treated at an academic medical center and non-profit community health center in Washington, D.C. The findings suggest that transgender patients taking gender-affirming hormone therapy should be monitored for changes in body weight, body mass index and for complications that may accompany high body weight, such as cardiovascular disease.
In a real-world trial, a team of clinician-researchers at Beth Israel Deaconess Medical Center have demonstrated that tests of self-collected saliva provided comparable results to tests performed by trained healthcare professionals using NP swabs.
With the goal of dramatically accelerating discoveries in health and disease, Beth Israel Deaconess Medical Center has opened a Spatial Technologies Unit, the first center in Massachusetts and one of the first of its kind worldwide. The new space will provide access to ground-breaking technologies that allow scientists to examine cells as they function within intact tissues. Made possible by a grant from the Massachusetts Life Sciences Center, the BIDMC unit will be a nexus of the state’s precision medicine community, empowering researchers across healthcare, academia, research and industry.
A study sheds new light on the complex interplay among the neurons that govern hunger, behavior and learning.
Researchers report that about a quarter of localized prostate cancers may demonstrate immunologic traits that suggest a substantial number of patients with prostate cancer may benefit from immunotherapies.
Researchers report on how a diverse cohort of gynecologic cancer patients are affected by financial distress, also called “financial toxicity” in acknowledgment of the health hazards it can pose, in the International Journal of Gynecological Cancer.
In a new study published in Nature, Dan Barouch, MD, PhD, Director of BIDMC's Center for Virology and Vaccine Research, and colleagues report on the antibody and cellular immune responses generated by the Ad26.COV2.S vaccine against the original viral strain and against SARS-CoV-2 variants of concern. The team found that this vaccine induced immune responses against all the viral variants.
In a new study from Beth Israel Deaconess Medical Center researchers evaluated the immunogenicity of COVID-19 mRNA vaccines in pregnant and lactating women who received either the Pfizer or Moderna COVID-19 vaccines. They found that both vaccines triggered immune responses in pregnant and lactating women.
May 2021 edition
In a recent perspective article, pathologists outline how the immunome — all of the genes collectively expressed by an individual's immune cells — holds the potential to provide researchers and physicians with unprecedented insight into an individual's health. Collecting that information from large numbers of patients could one day facilitate diagnostics via a near-universal blood test and pave the way to targeted therapies for a wide variety of conditions.
Researchers have successfully created the first 3D organoid models of the pancreas from human stem cells. This first-of-its-kind organoid model includes both the acinar and ductal structures that play a critical role in the majority of pancreatic cancers.
Study reveals that, while mother-to-newborn transmission of the virus is rare, newborns of expectant mothers with COVID-19 can suffer indirect adverse health risks as a result of worsening maternal COVID-19 illness.
In a randomized clinical trial published in the journal PAIN, researchers found participants with moderate to severe irritable bowel syndrome (IBS) who were knowingly treated with a pharmacologically inactive pill — referred to as an honest or open-label placebo — reported clinically meaningful improvements in their IBS symptoms.
In a research letter written by colleagues at Beth Israel Deaconess Medical Center (BIDMC) and published in the Journal of the American College of Cardiology, the authors report racial disparities improved only minimally in rural areas over the last two decades, with larger improvements occurring in urban areas.
Beth Israel Deaconess Medical Center has convened a team of experts to establish the Critical Illness and COVID-19 Survivorship Program, which treats patients with persistent symptoms, which are also described as “long-COVID” or “post-acute sequelae of COVID-19 (PASC).”
The team at Beth Israel Deaconess Medical Center demonstrated that COVID-19 cases resulted in significantly more weekly hospitalizations, more use of mechanical ventilation and higher mortality rates than influenza.
A study led by Beth Israel Deaconess Medical Center physician-researchers provides new, much-needed data about the optimal physical distancing between students for the prevention of COVID-19 in the school setting.
A team of researchers at Beth Israel Deaconess Medical Center (BIDMC) has developed a mathematical means of assessing tests’ false-negative rate.
In a new study led by an interdisciplinary team of gerontologists, geriatricians, precision medicine experts, and bioinformaticians at Beth Israel Deaconess Medical Center (BIDMC), researchers identified a single protein present in the blood that is associated with increased risk of post-operative delirium.
Seward Rutkove, MD, has been named Chair of the Department of Neurology at Beth Israel Deaconess Medical Center (BIDMC). Starting March 1, Rutkove will lead the department’s cutting-edge patient care, clinical and translational research, as well as foster innovative approaches to diagnostics and delivery of care.
In a new study from Beth Israel Deaconess Medical Center (BIDMC), researchers analyzed data from the National Center for Health Statistics to compare the rate of cardiovascular-related deaths before and after the onset of the pandemic in the United States, relative to the same periods in the prior year.
The COVID-19 pandemic has fundamentally disrupted U.S. healthcare organizations.
In a new study published in Clinical Trials, researchers led by Stephen Juraschek, MD, PhD (Medicine, BIDMC) compared four electronic-based and four traditional recruitment methods for clinical trials to determine how different strategies may impact enrollment of groups traditionally under-represented in the medical literature.
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