A machine learning algorithm that predicts suicide attempt recently underwent a prospective trial at the institution where it was developed, Vanderbilt University Medical Center.
Amid the COVID-19 pandemic, children’s hospitals across the United States have seen signification reductions in the number of children being treated for common pediatric illnesses like asthma and pneumonia, according to a new multicenter study led by Monroe Carell Jr. Children’s Hospital at Vanderbilt.
Strong, collaborative relationships with principal investigators are a key factor of longevity in clinical research coordinator positions — an essential, but increasingly transient job in executing treatment-advancing clinical trials, Vanderbilt University Medical Center researchers found.
A monoclonal antibody “cocktail” developed at Vanderbilt University Medical Center (VUMC) to neutralize the COVID-19 virus is effective against all known strains, or variants, of the virus, according to a report published in the journal Nature Medicine.
A neurostimulator surgically implanted above the buttocks to reprogram how the bladder senses the filling of urine is helping patients with debilitating bladder and bowel disorders that are often life-limiting.
And while students and parents alike are looking forward to the return to in-person learning, a child and adolescent psychiatry expert at Monroe Carell Jr. Children's Hospital at Vanderbilt says they should expect some challenges.
Delirium, a form of acute brain dysfunction, is widespread in critically ill patients in lower resourced hospitals, and the duration of delirium predicted both mortality and disability at six months after discharge, according to a study published in PLOS ONE.
Treatment with convalescent plasma vastly improved the survival rate of patients hospitalized for COVID-19 who also had hematologic malignances that compromise the immune system, according to new data released by the COVID-19 and Cancer Consortium (CCC19).
A study published today in the New England Journal of Medicine provides the most definitive evidence to date that, of the two drugs recommended for light sedation of patients receiving mechanical ventilation in the ICU, one is as effective and safe as the other.
The Vanderbilt Transplant Center (VTC) established a new record in 2020 for total solid organ transplants, performing 611 life-saving procedures among its adult and pediatric organ transplant programs.
The latest Vanderbilt Child Health Poll release found that many Tennessee parents are worried about the mental health of their children during the COVID-19 pandemic, and over 80% of parents had concerns about their children attending school remotely. The Poll also revealed that schooling practices and mental health concerns have varied widely among Tennessee families of different racial and economic groups.
Vanderbilt University Medical Center performed more heart transplants in 2020 than any other center in the world — 124 adult hearts, 23 pediatric hearts and VUMC’s first heart-lung transplant since 2006.
A unifying explanation of the cause of autism and the reason for its rising prevalence has eluded scientists for decades, but a theoretical model published in the journal Medical Hypotheses describes the cause as a combination of socially valued traits, common in autism, and any number of co-occurring disabilities.
The Vanderbilt study, COVID-19 Myocardial Pathology Evaluation in AthleTEs with Cardiac Magnetic Resonance (COMPETE CMR), found a much lower degree of myocarditis in athletes than what was previously reported in other studies.
Injury Prevention experts at Monroe Carell Jr. Children’s Hospital at Vanderbilt want to raise awareness on the importance of safely heating your home.
And with a boom in online shopping due to COVID-19, injury prevention advocates want to raise awareness about the need for gift-givers to be more mindful of online toy purchases.
Younger parents were much less likely than older parents to say they planned to vaccinate their children and themselves against COVID-19, according to a research letter published online in medRxiv by authors at the Vanderbilt University School of Medicine and Ann & Robert H. Lurie Children’s Hospital of Chicago and Northwestern University Feinberg School of Medicine.
A new Vanderbilt-designed prediction model may make it easier to determine which infants will go on to develop neonatal abstinence syndrome (NAS), a drug withdrawal syndrome in newborns that occurs after exposure to opioids during pregnancy.
The findings, published today in the Journal of Clinical Investigation, support efforts to block the enzyme to potentially treat or prevent COVID-19 in older people.
Findings from a national study published today in the Journal of the American Medical Association (JAMA) “do not support” the use of hydroxychloroquine for the treatment of adult patients hospitalized with COVID-19.
AstraZeneca is advancing into phase 3 clinical trials with an investigational COVID-19 therapy of two long-acting antibodies discovered by Vanderbilt University Medical Center (VUMC) and optimized by AstraZeneca.
Leaders of Vanderbilt University Medical Center (VUMC) today announced plans to purchase Tennova Healthcare-Shelbyville and Tennova Healthcare-Harton hospitals from subsidiaries of Community Health Systems, Inc. (CHS). At the same time, VUMC will acquire minority ownership in CHS’s Tennova Healthcare-Clarksville hospital.
Vanderbilt University Medical Center (VUMC) is now enrolling volunteers for a clinical trial of promising treatments for COVID-19 in the outpatient setting. The trial is part of the national ACTIV-2 protocol to evaluate the safety and efficacy of new potential therapeutics in adult patients who have COVID-19 illness but are not hospitalized.
Vanderbilt University Medical Center (VUMC) has been awarded a one-year, $34-million grant by the National Center for Advancing Translational Sciences, part of the National Institutes of Health, to conduct a nationwide study of “convalescent plasma” as a treatment for COVID-19.
The “secret shopper” study used trained actors attempting to get into treatment with an addiction provider in 10 U.S. states. The results, with more than 10,000 unique patients, revealed numerous challenges in scheduling a first-time appointment to receive medications for opioid use disorder, including finding a provider who takes insurance rather than cash.
Patients with ALK-positive non-small cell lung cancer treated with ensartinib fared better and lived longer than those who received crizotinib, according to results of a phase 3 study. The randomized study compared the targeted therapies as first-line treatments. Ensartinib is a newer targeted therapy that was initially tested and validated at a Vanderbilt-Ingram Cancer Center research laboratory, while crizotinib received approval in 2011 from the U.S. Food and Drug Administration (FDA).
Each week a woman consumes alcohol during the first five to 10 weeks of pregnancy is associated with an incremental 8% increase in risk of miscarriage, according to a study published today by Vanderbilt University Medical Center (VUMC) researchers.
When COVID-19 cases began rising in Nashville, masking became a regular part of life across Vanderbilt University Medical Center and Children’s Hospital as one of several public health safety measures to protect employees and patients from potential COVID-19 exposure.
Children’s Hospital decided to get creative to ensure that the 1,700 children and families who visit the hospital and clinics each day can see that the same friendly faces they’ve always known still exist behind the masks.
The Vanderbilt Health website now features an out-of-pocket cost estimator for many hospital and professional services offered by Vanderbilt University Medical Center. Anyone with an internet connection can use the new online tool to generate immediate estimates, with no website registration required.
Post-surgical bleeding is associated with more deaths than blood clots from surgery, according to a Vanderbilt University Medical Center study published in the journal Anesthesia & Analgesia.
A $500,000 KidneyX prize has been awarded to The Kidney Project — a collaboration between Vanderbilt University Medical Center (VUMC) and UC San Francisco (UCSF) — for the development of an implantable dialysis system that would enable patients to safely and effectively treat kidney failure at home.
Grammy Award-winning country music artist Kix Brooks is the new chair of Monroe Carell Jr. Children's Hospital at Vanderbilt Advisory Board, effective July 1, taking over for outgoing chair Allison DeMarcus. Louise Adams, who succeeds Judge Les Smith, was recently named the chair of the Vanderbilt Eye Institute (VEI) Advisory Board.
Taking new actions that focus on the well-being and safety of customers and team members, American Airlines today announced that it has created a new Travel Health Advisory Panel that includes Vanderbilt University Medical Center (VUMC) infectious disease experts to advise on health and cleaning matters as travelers return over the summer.
Erlanger Health System and Vanderbilt University Medical Center, on behalf of Vanderbilt-Ingram Cancer Center (VICC), have entered into an agreement to design a long-term collaboration in cancer care, including VICC hematology-oncology services at Erlanger's two clinic and infusion locations.
Researchers at Vanderbilt University Medical Center’s (VUMC) Center for Biomedical Ethics & Society were recently awarded a grant from the National Human Genome Research Institute (NHGRI) of the National Institutes for Health (NIH) to explore LGBTQ+ perspectives on a range of issues related to biomedical research.
The Outcomes Related to COVID-19 Treated with Hydroxychloroquine among In-patients with Symptomatic Disease (ORCHID) trial stopped enrolling new patients based on the fourth scheduled interim analysis showing no evidence of benefit or harm.
As the world begins to slowly open back up after months of living in a safer-at-home mode, many families are wondering how best to re-introduce their children to society.
Using electronic health record data to simulate drug trials for pregnant patients could one day offer a solution to the current practice of delivering babies, even if they are pre-term, if the mother contracts COVID-19, according to a position paper published in Nature Medicine.
In the first such procedures in Tennessee, Vanderbilt University Medical Center has successfully used technology to bring two donor hearts that stopped beating back to life before transplanting them into patients.
An investigational drug that binds bile acids in the stomach can reduce the severity of heartburn symptoms in patients with treatment-resistant gastroesophageal reflux disease (GERD) when combined with a proton pump inhibitor (PPI), a new study suggests.
A Polygenic Risk Score — a genetic assessment that doctors have hoped could predict coronary heart disease (CHD) in patients — has been found not to be a useful predictive biomarker for disease risk, according to a Vanderbilt study published in the Journal of the American Medical Association.
The John D. and Catherine T. MacArthur Foundation today unveiled a grant proposal from Vanderbilt University Medical Center (VUMC) as one of the highest-scoring proposals, designated as the “Top 100,” in its 100&Changecompetition for a single $100 million grant to help solve one of the world’s most critical societal challenges.
Black men with high blood pressure could benefit from a research study beginning this month to check their vitals while they are getting a haircut at a barbershop.
Most Tennessee infants exposed to hepatitis C at birth are not later tested to see if they acquired the virus, according to a study by researchers at Monroe Carell Jr. Children’s Hospital at Vanderbilt and the Vanderbilt Center for Child Health Policy.
Emergency Medicine and Trauma Surgery researchers at Vanderbilt University Medical Center (VUMC) are joining the Nashville Fire Department and nearly two dozen emergency medical service agencies across the country in a Department of Defense (DOD)-funded clinical trial aimed at improving survival with breathing techniques used to keep patients alive at the scene of a trauma.
VICC is the first cancer center to enroll a patient in a clinical trial for this new technology developed by SQZ Biotechnologies of Watertown, Massachusetts. The investigational product is generated from the company’s technology that uses high-speed cell deformation to squeeze cells, creating a temporary disruption of their membranes and offering a window for the insertion of tumor antigens.
High levels of protein in a patient’s urine shortly after an episode of acute kidney injury is associated with increased risk of kidney disease progression, providing a valuable tool in predicting those at highest risk for future loss of kidney function.
The CEASAR (Comparative Effectiveness Analysis of Surgery and Radiation for Localized Prostate Cancer) study, coordinated by Vanderbilt University Medical Center, is a multi-site research study conducting long-term followup on men who were diagnosed with localized prostate cancer between 2011 and 2012.
The benefits of fetal surgery to repair spina bifida, a procedure pioneered at Vanderbilt University Medical Center (VUMC) in 1997, continue through school age, a National Institutes of Health (NIH) study reports today in the journal Pediatrics.