The pacemaker has taken on an increasingly important role in recent years. Originally used to fix electrical abnormalities in people with irregular heart rhythms, it is now in favor for heart failure patients as a way to "resynchronize" a weak and struggling heart.
While scientists at Johns Hopkins and Kings College don't enjoy being nay-sayers at the parade of potential benefits suggested by the Human Genome Project, they say we may, in part, be seeing what we want to see (NEJM, 7-13-00).
A study by Johns Hopkins researchers shows that women carry lower levels of HIV in their blood than men but have the same risk as men of developing AIDS. Viral load thresholds used by doctors to begin anti-retroviral drug therapy could result in more men getting offered treatment than women, particularly early in the course of infection.
A new family of genes that contributes to the process of malignancy, shedding new light on the abnormalities that give rise to the aggressive childhood cancer, Burkitt's lymphoma -- as well as lymphoma, leukemia, prostate, ovarian, lung and breast cancer -- has been discovered by a Johns Hopkins research team (Molecular and Cellular Biology, 8-00).
The more eye pressure fluctuates during the day, the higher the risk that a glaucoma patient will lose vision, according to a study by researchers at Johns Hopkins and two other academic medical centers (Journal of Glaucoma).
The function of a group of nerve fibers that originates in the brain stem and fires off signals even before newborn rats can hear has been discovered by Johns Hopkins scientists. The signals may be a process for wiring the ears and brain for hearing, much like laying down circuits on a computer chip (Science, 6-30-00).
A compound called C75 that is capable of rapidly turning off appetite in mice and causing weight loss similar in many ways to that achieved by fasting has been produced by Johns Hopkins scientists (Science, 6-29-00).
In what seems at first an obvious conclusion, researchers at Johns Hopkins and The National Institute on Drug Abuse have found that people who "do" both cocaine and alcohol risk a worse loss of brain function than those who frequently use either drug alone (Neurology, 6-26-00).
Amino acid supplements may provide a cost-effective and safe method for improving the nutritional intake of some dialysis patients who are unable to meet their daily protein requirements, a Johns Hopkins study shows (Kidney International, 6-00).
Press reports suggest that after several years' competition, the public and private laboratories vying to create a working draft of the human genetic instructions -- the genome -- will jointly announce their progress on Monday (6-26-00).
AEGON has committed $2 million to Johns Hopkins for prostate and breast cancer research. The Oncology Center will split the funds with the Free University Oncology Research Institute in Amsterdam for a collaborative research project.
Many people decline to have a tracheotomy for severe, obstructive sleep apnea because they loathe the idea of having a quarter-sized opening in their neck. A study in the June American Journal of Respiratory and Critical Care Medicine proves that a tiny 2-mm opening can work as well when combined with a new technology to monitor the flow of air.
In older adults with psychiatric problems, a four-year Johns Hopkins study has shown that combining observations by janitors, building managers and others who frequently see elderly people and the skills of a highly accessible psychiatric nurse can significantly increase seniors' mental health and stability (JAMA, 6-6-00).
Successfully using behavioral techniques to keep drug addicts abstinent, Johns Hopkins researchers have formed a non-profit data processing company to employ the addicts and provide them with monetary incentives to stay off drugs.
These news tips are based on abstracts or posters being presented at the annual meeting of the American Society of Clinical Oncology.
A substance found in dark green leafy vegetables and egg yolks may improve vision in people with retinitis pigmentosa and other degenerative eye conditions, according to a study published by a Johns Hopkins researcher (Optometry, 3-00).
The age-old stigma against people with epilepsy is alive and well in the print media. That's the consensus of neurologists at Johns Hopkins and the University of Maryland who screened several hundred recent popular press articles on epilepsy/seizures for misinformation or outright errors (Neurology, 5-00).
Johns Hopkins researchers have discovered that a nervous system protein may have a significant role in asthma, hay fever and other allergies. According to the May American Journal of Respiratory and Critical Care Medicine, the protein, nerve growth factor, may be responsible for making allergy sufferers more sensitive to irritants such as tobacco smoke.
With a more healthy diet and less salt, individuals can dramatically lower their blood pressure, according to a nationwide study at Johns Hopkins and four other academic medical centers.
Contrary to general belief among doctors, clot-busting drugs -- the main emergency treatment for heart attack victims -- fail to benefit patients more than 75 years old and may actually increase their risk of death, according to a Johns Hopkins-led study (Circulation, 5-16-00).
For landmark discoveries of how human cells respond to hypoxia, Gregg L. Semenza of the Johns Hopkins Children's Center and Johns Hopkins Institute of Genetic Medicine received the annual E. Mead Johnson Award, for pre-eminent contributions to American pediatrics.
Two Johns Hopkins Children's Center studies confirm that prenatal exposure to normal male hormones alone dictates male gender identity in normal XY male babies, even if they are born without a penis.
Patients and physicians with questions about digestive diseases now can turn to a newly launched website for answers; the Johns Hopkins Division of Gastroenterology and Hepatology announces the launch of their in-depth Gastroenterology and Hepatology Portal.
1- common lung exam often causes unnecessary pain: more pain control needed, 2- quicker asthma diagnoses may lower hospital admission rates for elderly: based on research expected to be presented at the American Thoracic Society Conference May 5-10 in Toronto.
The sexually transmitted human papillomavirus has been found by Johns Hopkins researchers to be a likely cause of certain cancers of the head and neck and also an indicator of improved survival (Journal of the National Cancer Institute, 5-3-00).
At least half of the extra risk for diabetes faced by African-American women is linked to relatively simple and modifiable lifestyle factors; the same was not true for African-American men, according to a study team led by Johns Hopkins investigators (JAMA, 5-3-00).
Johns Hopkins scientists have found that individuals who have the misfortune to be allergic to cats can find welcome relief and protection from symptoms in one of a new class of drugs already known to help other asthmatics (Journal of Allergy and Clinical Immunology, 4-00).
A new metabolic pathway in a parasite that could lead to drugs for treating so-called African sleeping sickness has been discovered by Johns Hopkins researchers (Science, 4-7-00).
Johns Hopkins research news highlights from presentations or are ongoing issues that provide context for presentations at the annual meeting of the American Association of Cancer Research.
Asthma and allergy research efforts have been aimed at attempting to improve efficacy, increase safety, decrease treatment time and improve compliance; Johns Hopkins, the University of California at San Diego, and Dynavax Technologies Corporation researchers announce that they have developed a method of modifying an allergen to create a vaccine that may solve many concerns.
Johns Hopkins and Sisters Together and Reaching Inc. have teamed up to offer Baltimoreans free HIV urine testing from a mobile van, which will operate five days and evenings per week and patrol areas at high risk for HIV.
People with high blood pressure are 2-1/2 times more likely to develop Type 2, or non-insulin-dependent, diabetes than those with normal blood pressure, according to a study led by Johns Hopkins researchers (NEJM, 3-30-00).
People with HIV infections are less likely to pass the virus to an opposite sex partner if they have low levels of the virus in their blood, according to a study by researchers from Johns Hopkins, NIH, Makerere University, the Uganda Virus Research Institute, and Columbia University (NEJM, 3-30-00).
Johns Hopkins researchers have discovered a phenomenon in the brains of individuals with schizophrenia and other mental illnesses that may help doctors develop better drugs (Molecular Psychiatry, 3-00).
The enzyme telomerase is an ideal target for anti-cancer therapy because it is active in cancer cells, which need it to divide; biotech companies have pumped millions into finding a telomerase inhibitor (Cell, 3-00).
In the continuing debate among emergency medical services personnel regarding the best pre-hospital management for trauma patients, a study by Johns Hopkins and the University of Southern California raises the bar on the importance of time (Archives of Surgery, 3-00).
Infectious disease experts at Johns Hopkins conclude that public health doctors do a far better job of treating tuberculosis than private-practice physicians (CHEST, 3-00).
Altering the way mechanical ventilators are used to treat patients with acute lung injury and acute respiratory distress syndrome significantly reduces deaths from the disease (NEJM, 3-10-00).
A very rare but deadly form of heart disease, fulminant myocarditis, is underdiagnosed; a Johns Hopkins-led study finds that patients who are properly diagnosed and treated aggressively can fully recover from the condition within two weeks (NEJM, 3-9-00).
A new twist on the standard way to predict prostate cancer risk appears to offer African-American men a much-needed, improved accuracy in detecting the disease (Urology, 3-00).
Schizophrenia typically runs a far nastier course in men than in women; now a new Hopkins study suggests that basic differences between men and women in the way the disease rearranges the brain may be responsible (American Journal of Psychiatry, 3-00).
HIV/AIDS statistics are driving the work of researchers and healthcare workers attending the 2000 National Conference on African-Americans and AIDS, Feb. 23-25.
Evidence for a credible animal version of Down syndrome mounted today with Johns Hopkins scientists verifying the syndrome's signature skull and facial deformities in a genetically modified mouse (Developmental Dynamics, 1-00).
Johns Hopkins scientists report a new way of monitoring brain damage that could significantly increase the number of stroke patients eligible for -- and helped by -- clot-breaking treatments.
In the 2-10-00 Science, Johns Hopkins researchers identify a protein that accumulates toward the front end of a cell and helps cells "sense" their way to a target.
A natural chemical substance the eye calls for when it lacks oxygen is responsible for the blinding blood vessel growth that plagues patients with diabetic retinopathy, report Johns Hopkins and CIBA Vision Corp. researchers (American Journal of Pathology, 2-00).
Half of the baby boomers, who are now approaching the Medicare years, have been divorced, and researchers at Johns Hopkins have found that elderly people with divorce in their lives will get less care from their children than people who do not (Demography, 1999).
Researchers at Johns Hopkins think they may have identified both the nervous system mechanism linked to Huntington's disease tremors and jerky movements and the part of the brain causing them (Nature, 2-3-00).
An important link between getting specific bacterial infections and developing autoimmune diseases such as arthritis has been uncovered by Johns Hopkins scientists (Nature Medicine, 2-00).
The first known case of tuberculosis transmitted from a cadaver to an embalmer is reported by Johns Hopkins researchers in the Jan. 27 issue of the New England Journal of Medicine.
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