Findings are from a systematic review and meta-analysis. Data from 20 randomized controlled trials, which included a total of almost 12,000 patients, were analyzed in the study, providing strong and clear evidence in support of triple-drug therapy.
Five years after the disastrous wildfire in Fort McMurray, Alberta, researchers are warning that the complex role of peatlands, a factor critical to projecting the risk and behaviour of future fires, is missing from the forecasting model.
Kolb is research director at the Firestone Institute for Respiratory Health at McMaster and St. Joseph’s Healthcare Hamilton, as well as division director for respirology at the Department of Medicine. He is also the European Respiratory Journal’s chief editor.
A team of McMaster University researchers who studied heart patients found that stair-climbing routines, whether vigorous or moderate, provide significant cardiovascular and muscular benefits.
Using an epigenetic clock, the researchers looked at the genes of 45 of those who were ELBW babies along with 47 who were normal birth weight when they were age 30 to 35 to compare their biological age, controlling for chronic health problems and sensory impairments.
The study tracked 4,811 people in 27 countries who are living with atrial fibrillation and taking blood thinners. Consenting patients undertaking cardiopulmonary bypass surgery were randomly selected for the additional left atrial appendage occlusion surgery; their outcomes compared with those who only took medicine. They were all followed for a median of four years.
Researchers examined prenatal stool (meconium) samples collected from 20 babies during breech Cesarean delivery. By including only breech caesarean deliveries in healthy pregnant women they were able to avoid the transmission of bacteria that occurs naturally during a vaginal birth.
The international guideline panel included 22 health-care professionals, school administrators, and parents of children with and without food allergy, along with a team of six researchers with methodology expertise. A systematic literature review of practices for managing food allergy in schools found a lack of high-quality evidence, so the guideline recommendations are graded as conditional.
McMaster University researchers Ali Ashkar and Sophie Poznanski have uncovered that changing the metabolism of natural killer (NK) immune cells allows these cells to overcome the hostile conditions found inside tumours and destroy advanced ovarian and lung cancer.
A new grant is helping McMaster University engineers and a Toronto precision-medicine diagnostics company to get infection-testing technology to market while generating opportunities for students.
Ontario doctors are still hesitant to prescribe medical cannabis to patients suffering long-term pain 20 years after it was first introduced, says a new study carried out at McMaster University.
The pandemic has created a paradox where mental health has become both a motivator for and a barrier to physical activity.
People need to rethink what they stock in their home cabinets as allergy medicines, what hospitals keep on formulary, and what policymakers recommend. The message needs to get out. This publication is on time for the spring allergy season and as COVID vaccines roll out, for which rashes are common and antihistamines can be helpful
AIEC bacteria grow in a biofilm that coats cells lining the intestinal wall, protecting them from both the immune system and antibiotics. In this research, the team identified a critical protein structure on the surface of the bacteria that allow them to grow in biofilms.
The information comes from the diets and health outcomes of 134,297 people from 21 countries spanning five continents, who were tracked by researchers for data on meat consumption and cardiovascular illnesses. After following the participants for almost a decade, the researchers found consumption of 150 grams or more of processed meat a week was associated with a 46 per cent higher risk of cardiovascular disease and a 51 per cent higher risk of death than those who ate no processed meat. However, the researchers also found moderate levels of consumption of non-processed meats had a neutral effect on health.
Blood from critically ill COVID-19 patients contains antibodies that can contribute to clotting. These antibodies form immune complexes that activate platelets, the cells that lead to blood clot formation. Some blood-thinner medications can block these immune complexes and potentially reduce clots.
The study used data collected from 44,817 participants enrolled in the Canadian Longitudinal Study on Aging (CLSA), a large, national population-based study of health and aging. The participants completed questionnaires about adverse childhood experiences through telephone and face-to-face interviews between 2015 and 2018.
The study will involve more than 2,000 residents, staff, and visitors of long-term care homes in Ontario over the course of a year. Blood and saliva will be examined.
An analysis of several large studies involving participants from more than 60 countries, spearheaded by researchers from McMaster University, has found that eating oily fish regularly can help prevent cardiovascular disease (CVD) in high-risk individuals, such as those who already have heart disease or stroke.
The study, involving 281 Ontario children, found that 85.7% of those who received the short course of antibiotics and 84.1% of those who received the longer course of medication were cured two to three weeks later.
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