Infants born prematurely are at risk for injuries to the white and gray matter of the brain that affect cortical development and neural connectivity. Certain forms of these injuries can be detected in the neonatal period using ultrasound, according to Columbia University Medical Center researchers.
Dental visits represent a chance to intervene in the diabetes epidemic by identifying individuals with diabetes or pre-diabetes who are unaware of their condition, according to a study in the July 2011 issue of the Journal of Dental Research.
A new study has found that most patients undergoing biopsy of the small intestine do not have the recommended number of samples to diagnose celiac disease.
Idiopathic pulmonary fibrosis (IPF)―scarring and thickening of the lungs from unknown causes―is the predominant condition leading to lung transplantation nationwide. Columbia University Medical Center researchers confirmed that delayed access to a tertiary care center for IPF is associated with a higher risk of death.
CUMC scientists have found that under stress, neural stem cells in the adult hippocampus can produce not only neurons, but new stem cells. The brain stockpiles the stem cells, which may produce neurons when conditions are favorable. The research could lead to potential treatment for neurodegenerative diseases such as Alzheimer’s and Parkinson’s.
Less invasive catheter-based aortic valve replacement and open valve-replacement surgery have a similar one-year survival for patients at high risk for surgery.
Researchers at Columbia University Medical Center are honing in on the development of what may be the first non-steroidal, oral contraceptive for men. Tests of low doses of a compound that interferes with retinoic acid receptors (RARs) showed that it caused sterility in male mice.
Slowing down the aggregation or “clumping” of vitamin A in the eye may help prevent vision loss caused by macular degeneration, research from Columbia University Medical Center has found.
Many genes that cause human diseases have parallel genes in other organisms, including yeast. Now Columbia University researchers have used an innovative yeast-based screening method to identify a possible treatment for the fatal childhood disease Niemann-Pick C (NP-C). This “exacerbate-reverse” approach can potentially be used to study any disease. The findings were published online in the Journal of Biological Chemistry on April 13, 2011.
Researchers from a consortium that includes Columbia University Medical Center identified four new genes linked to late-onset Alzheimer’s disease, each of which adds to the risk of developing this most common form of the disease. Together they offer a portal into the causes of Alzheimer’s. Their identification will help researchers find ways to determine who is at risk of developing the disease and to identify proteins and pathways for drug development.
Researchers at Columbia University Medical Center have developed a new way to stimulate neuron production in the adult mouse brain, demonstrating that neurons acquired in the brain's hippocampus during adulthood improve certain cognitive functions.
Columbia University’s Mailman School of Public Health and the International Longevity Center (ILC) announced that the ILC, founded by Robert N. Butler, will be the foundation of an interdisciplinary center on aging at Mailman. The center will be a research and educational hub for issues related to healthy aging in NYC, the U.S., and globally.
Researchers at Columbia University Medical Center have discovered that the skeleton acts as a regulator of fertility in male mice through a hormone released by bone, known as osteocalcin. Until now, interactions between bone and the reproductive system have focused only on the influence of gonads on the build-up of bone mass.
Columbia University Medical Center has announced the winners of the 5th annual Katz Prizes in Cardiovascular Research, with the 2010 Lewis Katz Visiting Professorship in Cardiovascular Research being awarded to an internationally renowned heart failure expert from University of Texas Southwestern Medical Center – Milton Packer, M.D.
Researchers from the Columbia University Medical Center and colleagues from the NewYork-Presbyterian/Weill Cornell Medical Center, JFK Johnson Rehabilitation Institute, and Harvard Medical School Department of Physical Medicine and Rehabilitation at the Spaulding Rehabilitation Network have a functional MRI study in the current edition of Neurology. Conventional bedside assessments of consciousness rely on motor responses to indicate awareness and therefore may underestimate capacity for cognition, the researchers say.
Volunteers in New York, NY are being sought for a clinical study examining the subtle changes that may take place in the brains of older people many years before overt symptoms of Alzheimer’s disease (AD) appear. Researchers at Columbia University Medical Center are specifically looking for people with the very earliest complaints of memory problems that affect their daily activities.
A new study in mouse models by researchers at Columbia University Medical Center has found that the brain’s mitochondria -- the powerhouses of the cell -- are one of the earliest casualties of the disease. The study, which appeared in the online Early Edition of PNAS, also found that impaired mitochondria then injure the neurons’ synapses, which are necessary for normal brain function.
Columbia University Medical Center announced a major gift of $50 million from a respected alumnus of its medical school, P. Roy Vagelos, M.D., and his wife, Diana Vagelos. The gift will support the construction of a new medical and graduate education building, which will be built on the medical center campus and named in their honor.
A new study led by researchers at Columbia University Medical Center has identified a novel molecular pathway underlying Parkinson’s disease and points to existing drugs which may be able to slow progression of the disease. The pathway involved proteins – known as polyamines – that were found to be responsible for the increase in build-up of other toxic proteins in neurons, which causes the neurons to malfunction and, eventually, die. The study is the first to identify a mechanism for why polyamines are elevated in the first place and how polyamines mediate the disease.
Researchers led by Columbia University Medical Center have discovered that the skeleton plays an important role in regulating blood sugar and have further illuminated how bone controls this process. The finding, published in Cell, is important because it may lead to more targeted drugs for type 2 diabetes.
A team of Columbia-led investigators has uncovered eight genes that underpin alopecia areata, one of the most common causes of hair loss, as reported in a paper in the July 1 issue of Nature. This discovery may soon lead to new treatments for the 5.3 million Americans suffering from hair loss caused by alopecia areata.
A new study in the Journal of Clinical Oncology found that less than half of women (49%) in a large study (8,800 women) completed their full prescribed course of hormone therapy for breast cancer. Age was an important factor, with younger women less likely to adhere to treatment. Treatment side effects and insurance coverage may be among the causes.
A team of researchers led by NewYork-Presbyterian Hospital/Columbia University Medical Center has developed a method to predict post-stroke recovery of language by measuring the initial severity of impairment. Being able to predict recovery has important implications for stroke survivors and their families, as they plan for short and long-term treatment needs. Findings are reported online in the journal Stroke.
300 neurosurgeons from 22 of the nations’ top medical institutions will battle it out in NYC’s Central Park on Sat., June 5 – an annual event that provides an opportunity for neurosurgeons to trade in the operating room for the softball field for a day – to support Columbia University Medical Center’s Pediatric Brain Tumor Research Fund.
A technique pioneered in the Tissue Engineering and Regenerative Medicine Laboratory of Dr. Jeremy Mao, the Edward V. Zegarelli Professor of Dental Medicine at Columbia University Medical Center, can orchestrate stem cells to migrate to a three-dimensional scaffold infused with growth factor, holding the translational potential to yield an anatomically correct tooth in as soon as nine weeks once implanted.
300 neurosurgeons from 22 of the nations’ top medical institutions will battle it out in NYC’s Central Park on Sat., June 5 – an annual event that provides an opportunity for neurosurgeons to trade in the operating room for the softball field for a day – to support Columbia University Medical Center’s Pediatric Brain Tumor Research Fund.
Experts from the Department of Obstetrics & Gynecology, Columbia University Medical Center (CUMC) and NewYork-Presbyterian Hospital/Columbia (NYP) will present new research findings and up-to-date information from the field at The American College of Obstetricians and Gynecologists 2010 annual meeting (May 15-19, San Francisco).
Annual heart disease and stroke rates in China will rise by up to 73 percent by 2030, given an aging population and other increased risk factors, without policies and prevention efforts aimed at controlling blood pressure and smoking, according to research from Columbia University Medical Center published in Circulation: Cardiovascular Quality and Outcomes, an American Heart Association journal.
A team of investigators from Columbia, Rockefeller and Stanford Universities has identified a new gene involved in hair growth, as reported in a paper in the April 15 issue of Nature. This discovery may affect future research and treatments for male pattern baldness and other forms of hair loss.
Underscoring what researchers call a serious global public health concern, results from a new study of more than 60,000 women, led by Columbia University Medical Center reveal that many women at an elevated level of risk for osteoporosis-associated fractures fail to perceive the implications of the risk factors. Highlights need for public education about osteoporosis risk factors and treatment.
Columbia University Medical Center’s Department of Ophthalmology announces the opening of its new comprehensive eye care center in midtown Manhattan, the Gloria and Louis Flanzer Vision Care Center. Occupying the entire second floor of 880 Third Avenue at East 53rd Street, the new site will offer patients expert care in a beautiful and spacious setting, equipped with the latest in diagnostic and treatment technologies.
In what may provide the most compelling evidence to date, researchers at Columbia University Medical Center have illuminated how a genetic variant may lead to schizophrenia by causing a disruption in communication between the hippocampus and prefrontal cortex regions of the brain, areas believed to be responsible for carrying out working memory. Findings are published in the current online edition of Nature.
Columbia University College of Physicians and Surgeons and Weill Cornell Medical College are pleased to announce a major gift from The Mortimer D. Sackler Foundation to establish an endowed prize in developmental psychobiology. $100,000 Award Will Be Granted Jointly Every Two Years to Honor the Contributions of Mortimer D. Sackler, M.D., to Understanding the Biology of Psychiatric Illness.
A new study, led by researchers at the Herbert Irving Comprehensive Cancer Center at NewYork-Presbyterian Hospital/Columbia University Medical Center, demonstrates that acupuncture may be an effective therapy for joint pain and stiffness in breast cancer patients who are being treated with commonly used hormonal therapies. Results were published in the Journal of Clinical Oncology.
An investigational drug that inhibits serotonin in the gut, administered orally once daily, effectively cured osteoporosis in mice and rats. Serotonin in the gut has been shown in recent research to stall bone formation. The finding could lead to new therapies that build new bone; most osteoporosis drugs only prevent the breakdown of old bone.
A new NEJM study from Columbia University Medical Center researchers, has found that the heart's ability to pump effectively is diminished among people with a common lung disease, even in people with no or mild symptoms. The research is the first to show a strong link between heart function and mild COPD (chronic obstructive pulmonary disease).
Latinos are not all the same when it comes to risk of heart disease, and a new study by a Columbia University researcher shows key differences among Hispanic populations that doctors should take into account in trying to stem the risk of cardiovascular disease in this large and growing subset of the U.S. population.
An excess of one type of serotonin receptor in the center of the brain may explain why antidepressants fail to relieve symptoms of depression for 50 percent of patients, a new study from researchers at Columbia University Medical Center shows.
A team of Columbia scientists have discovered two genes that, when simultaneously activated, are responsible for the most aggressive forms of human brain cancer. This finding was made possible by the assembly of the first comprehensive network of molecular interactions that determine the behavior of these cancer cells.
Lee Goldman, M.D., executive vice president for health and biomedical sciences and dean of the faculties of medicine and health sciences at Columbia University testified today on medical malpractice reform before the New York State Senate Committees on Codes, Health and Insurance in Albany, New York.
Columbia University Medical Center will present the 2009 Naomi Berrie Awards to a nationally recognized diabetes researcher, and a promising young investigator, for their outstanding achievements in diabetes research.
Medications given to cancer patients to reduce their risk of anemia are associated with an increased risk of deep vein thrombosis or pulmonary embolism, according to new research led by Dawn Hershman, M.D, M.S., co-director of the breast cancer program at the Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center.
Columbia University will award the 2009 Louisa Gross Horwitz Prize to longtime collaborators Victor R. Ambros, Ph.D. and Gary Ruvkun, Ph.D., for their discovery of microRNAs (miRNAs) – small molecules that are critical to gene regulation.
Research assembled over the last decade – now published in the Oct. 16 issue of Science – shows that high school students' pass rate on New York State standardized tests, called Regents examinations, can be significantly improved if they are among the lucky few to study under a teacher trained in Columbia University's Summer Research Program for Science Teachers.
In honor of the centennial celebration of the Neurological Institute of Columbia University Medical Center (CUMC) and NewYork-Presbyterian Hospital/Columbia (NYP/CUMC), a daylong neuroscience symposium and gala dinner is being held on Fri., Sept. 25, 2009.
Lawrence H. Schwartz, M.D., a radiologist best known for advancing the use of computed tomography (CT) and magnetic resonance imaging (MRI) in oncologic imaging, has been named chair of the Department of Radiology of Columbia University and radiologist-in-chief at NewYork-Presbyterian Hospital/Columbia.
In honor of the centennial celebration of The Neurological Institute of New York, part of Columbia University Medical Center and NewYork-Presbyterian Hospital, a daylong neuroscience symposium is being held on Friday, Sept. 25, 2009.
A new type of stem cell discovered in the prostate of adult mice can be a source of prostate cancer, according to a new study by researchers at the Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center and NewYork-Presbyterian Hospital.
New research from Columbia University Medical Center has illuminated a previously unknown leptin-serotonin pathway in the brain that simultaneously promotes appetite and bone mass accrual. The research, which explains how leptin – well-known appetite-suppressing hormone – acts in the brain, is published in the Sept. 4 issue of Cell.
Researchers from Columbia University Medical Center's Herbert Irving Comprehensive Cancer Center have identified a protein that activates brain stem cells to make new neurons "“ but that may be hijacked later in life to cause brain cancer in humans. The protein called Huwe1 normally functions to eliminate other unnecessary proteins and was found to act as a tumor suppressor in brain cancer.
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