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Released: 7-Apr-2006 5:10 PM EDT
Study Finds Protein Loss Linked to Colon Polyp Risk from Growth Hormone
University of North Carolina Health Care System

The use of growth hormone therapy has been linked in some people to an increased risk of colon polyps. New research points to gene loss as possible factor.

17-Mar-2006 4:00 PM EST
How Cells Return to Normal After Responding to Stress
University of North Carolina Health Care System

Research describes how cells recover from heat, cold and other stressful conditions. The findings could have implications for the development of new therapies for cardiovascular and neurodegenerative diseases.

6-Mar-2006 1:55 PM EST
Aspirin Beneficial Against Heart Disease in More Men than Previously Thought
University of North Carolina Health Care System

Taking aspirin to prevent coronary heart disease is beneficial and cost-effective for a wider range of men than is often recognized, a study from the University of North Carolina at Chapel Hill has found.

Released: 10-Feb-2006 1:30 PM EST
Study Sets Treatment Standard for Elderly with Colon Cancer
University of North Carolina Health Care System

One of the newest and most potent chemotherapies for colon cancer is as safe and effective for the elderly as it is for younger patients, based on a University of North Carolina at Chapel Hill-led data review.

Released: 26-Jan-2006 2:30 PM EST
UNC Scientists Discover ‘Gatekeeper’ Protein in Blood Clotting
University of North Carolina Health Care System

New research from the University of North Carolina at Chapel Hill School of Medicine has identified a protein that may control blood clotting by keeping blood platelets from sticking together.

17-Jan-2006 1:55 PM EST
Effective, Cheap Treatment for Cystic Fibrosis Lung Disease
University of North Carolina Health Care System

Working half a world away from each other, two teams of medical scientists have identified what they believe is a simple, effective and inexpensive treatment to reduce lung problems associated with cystic fibrosis, the leading fatal genetic illness among whites.

Released: 11-Jan-2006 2:00 PM EST
Health Seriously Declines, Disparities Increase as Youths Become Adults
University of North Carolina Health Care System

Can becoming an adult be hazardous to your health? A new study from the University of North Carolina at Chapel Hill Carolina Population Center indicates that may be the case, with leading health indicators showing serious declines as adolescents become adults.

Released: 22-Dec-2005 12:00 AM EST
Chromosome Regions Related to Alcohol Addiction Affect Smokers Behavior
University of North Carolina Health Care System

Chromosome regions containing genes related to alcohol addiction affect drinking behavior in smokers.

Released: 19-Dec-2005 3:50 PM EST
Novel Enzyme Offers New Look at Gene Regulation
University of North Carolina Health Care System

Scientists at the University of North Carolina at Chapel Hill have purified a novel protein and have shown it can alter gene activity by reversing a molecular modification previously thought permanent.

Released: 16-Dec-2005 2:30 PM EST
Cancer Support Cells May Evolve, Fuel Tumor Growth
University of North Carolina Health Care System

University of North Carolina at Chapel Hill scientists have demonstrated in a living organism that cancers may cause surrounding supportive cells to evolve and ultimately promote cancer growth.

Released: 29-Nov-2005 12:00 AM EST
Cellular Molecule Spurs Growth of Prostate Cancer, Target for Treatment
University of North Carolina Health Care System

University of North Carolina at Chapel Hill scientists have identified a molecule that stimulates the aggressive growth of prostate cancer. Findings suggest new treatment target.

Released: 15-Nov-2005 2:55 PM EST
Brain Activity Related to Processing Faces Is Similar in People with, without Autism
University of North Carolina Health Care System

New brain imaging research at the University of North Carolina at Chapel Hill indicates that when people with autism look at a face, activity in the brain area that responds is similar to that of people without autism.

Released: 7-Nov-2005 3:35 PM EST
Increased Suicide Rate with Possible Link to Nearby Industry Chemicals
University of North Carolina Health Care System

Sustained elevation of the suicide rate in a North Carolina county may be linked to releases of hydrogen sulfide and other airborne chemicals from a nearby paper mill and possibly other industrial sites, a new study indicates.

Released: 12-Oct-2005 11:35 AM EDT
Study Finds Protein Is Required for Human Chromosome Production
University of North Carolina Health Care System

Scientists at the University of North Carolina at Chapel Hill School of Medicine have identified an elusive protein that performs a necessary step in the production of human chromosomes.

Released: 10-Oct-2005 2:10 PM EDT
Altering Time of Breast Biopsy May Improve Mastectomy Reconstruction Process
University of North Carolina Health Care System

Altering the standard step-by-step procedure that takes women facing a mastectomy from diagnosis to surgery to reconstruction can improve the process and help in determining if immediate reconstruction is the best course of action, according to new research.

Released: 6-Oct-2005 12:00 AM EDT
Test Predicts Risk of Liver Scarring After Transplant
University of North Carolina Health Care System

A test may help identify liver transplant patients with hepatitis C who are at greatest risk for advanced cirrhosis, thereby allowing doctors to decide who should receive treatment that could save the transplanted organ.

Released: 23-Sep-2005 11:55 AM EDT
Study Points to Molecular Origin of Neurodegenerative Disorders
University of North Carolina Health Care System

New research from the University of North Carolina at Chapel Hill School of Medicine points to the possible molecular origin of at least nine human diseases of nervous system degeneration.

Released: 9-Sep-2005 2:25 PM EDT
Researchers Identify Core Traits Strongly Linked to Eating Disorders
University of North Carolina Health Care System

An international team of researchers led by investigators at the University of North Carolina at Chapel Hill and the University of Pittsburgh School of Medicine has identified six core traits that appear to be linked to genes associated with two common eating disorders: anorexia and bulimia nervosa.

Released: 25-Aug-2005 11:40 AM EDT
Protein’s Role in Cell Division, New Knowledge Into Tumor Growth
University of North Carolina Health Care System

Scientists at the University of North Carolina at Chapel Hill have identified a molecular protein's critical role in cell division and growth. Findings may offer new knowledge into the molecular mechanisms involved in tumor growth.

19-Aug-2005 2:25 PM EDT
Biopsy Method Helps Diagnose Cancer Progression of Large Breast Tumors
University of North Carolina Health Care System

New breast cancer research shows for the first time that even women with large breast tumors can benefit from a less invasive biopsy method that has been reserved until now for women with small breast cancers.

Released: 5-Aug-2005 2:15 PM EDT
New Role for Protein as Fundamental Inhibitor of Cell Movement
University of North Carolina Health Care System

Scientists have identified a protein that may inhibit cellular movement, or migration. The protein may be a likely target for new drug development aimed at decreasing tumor metastasis.

Released: 3-Aug-2005 2:10 PM EDT
Revised Classification System Effective for Predicting Breast Cancer Outcome
University of North Carolina Health Care System

A revised and commonly used system for classifying the seriousness of cancer is effective for predicting relapse and survival in women with breast cancer who receive chemotherapy prior to surgery, according to research.

Released: 26-Jul-2005 3:35 PM EDT
Combination Scanner and Detecting Spread, Recurrence of Head, Neck Cancer
University of North Carolina Health Care System

A highly powerful scanner combining two state-of-the-art technologies "“ computed tomography (CT) and positron emission tomography (PET) "“ may detect the spread of head and neck cancer more accurately than other widely used imaging examinations.

Released: 27-May-2005 2:00 PM EDT
UNC Launches Study of Liver Injury Caused by Drugs
University of North Carolina Health Care System

The University of North Carolina at Chapel Hill is one of five clinical centers nationwide to receive funds from the National Institutes of Health to study why good medications are sometimes bad for the liver.

Released: 25-May-2005 9:00 AM EDT
Protein Helps Regulate the Genes of Embryonic Stem Cells
University of North Carolina Health Care System

New research from University of North Carolina at Chapel Hill shows how a protein may be crucial to the regulation of genes in embryonic stem cells. Findings offer new ideas on disease states.

16-May-2005 10:00 AM EDT
Umbilical Cord-Blood Transplants Save Lives of Babies with Rare Genetic Disorder
University of North Carolina Health Care System

Umbilical cord-blood transplants save the lives of newborns with a rare genetic disorder called Krabbe's disease and helps their brains develop more normally, a study led by researchers at the University of North Carolina at Chapel Hill and Duke University Medical Center concludes.

Released: 18-May-2005 1:45 PM EDT
New Method of Administering Anti-cancer Drug May Be More Effective, Safer
University of North Carolina Health Care System

A novel way of administering an anti-cancer drug to bone-marrow transplant patients using continuous infusion may be more effective and safer than the method currently used, new study findings indicate.

Released: 5-May-2005 2:40 PM EDT
Routine Procedure During Childbirth Provides No Benefits
University of North Carolina Health Care System

According to a systematic review of existing studies, the surgical procedure known as an episiotomy, performed in up to 35 percent of U.S. vaginal births, usually provides no benefits.

Released: 21-Apr-2005 3:40 PM EDT
Enzyme Activity Promotes Form of Leukemia, Offers Target for New Drugs
University of North Carolina Health Care System

Scientists have identified an enzyme that helps trigger the development of leukemia, a cancer of blood cells. The enzyme hDOT1L activates a set of genes that plays a key role in the rare and largely incurable acute myeloid leukemia.

Released: 20-Apr-2005 1:00 PM EDT
Gene Associated with Breast Cancer May Play Major Role in Prostate Cancer Recurrence
University of North Carolina Health Care System

A gene associated with breast cancer also may play a major role in the recurrence of prostate cancer, according to new research from the University of North Carolina at Chapel Hill School of Medicine and UNC Lineberger Comprehensive Cancer Center.

Released: 6-Apr-2005 2:35 PM EDT
U.S. Service Academies to Collaborate in Knee Injury Study
University of North Carolina Health Care System

The U.S. Army, Navy and Air Force academies -- fierce rivals on the sports field -- soon will cooperate on a $2.8-million study of risk factors for a common knee injury among athletes.

Released: 4-Apr-2005 2:20 PM EDT
Light Therapy Effectively Treats Mood Disorders, Including SAD
University of North Carolina Health Care System

A study commissioned by the American Psychiatric Association and led by a psychiatrist has found that light therapy effectively treats mood disorders, including seasonal affective disorder (SAD) and other depressive disorders.

Released: 16-Mar-2005 2:50 PM EST
Brain Imaging Study May Hold Clues to Onset of Schizophrenia in People at High Risk
University of North Carolina Health Care System

Images of brain activity may hold clues to the onset of schizophrenia in people at high risk for the disease, according to a study headed by psychiatry researchers at the University of North Carolina at Chapel Hill School of Medicine.

28-Feb-2005 1:40 PM EST
Findings May Help Explain Cause of Most Common Movement Disorder
University of North Carolina Health Care System

Scientists at the University of North Carolina at Chapel Hill may have identified the genetic basis underlying essential tremor disease, the most common human movement disorder.

Released: 15-Feb-2005 2:00 PM EST
Embryonic Stem Cells Treated with Growth Factor Reverse Hemophilia in Mice
University of North Carolina Health Care System

Mouse embryonic stem cells treated in culture with a growth factor and then injected into the liver reverse a form of hemophilia in mice analogous to hemophilia B in humans, a study from the University of North Carolina at Chapel Hill shows.

Released: 4-Jan-2005 2:00 PM EST
Study Pinpoints Protein's Role in Heart Failure Prevention
University of North Carolina Health Care System

Scientists at the University of North Carolina at Chapel Hill School of Medicine have shown that a protein in cardiac muscle cells may play a crucial role in heart failure prevention.

Released: 10-Dec-2004 12:30 PM EST
Increased Suicide Rate and Chemicals Released from Asphalt Plants
University of North Carolina Health Care System

Exposure to low levels of hydrogen sulfide and possibly other airborne chemicals from nearby asphalt plants may have contributed to an increased suicide rate in a North Carolina community, a study suggests for the first time.

15-Nov-2004 5:00 PM EST
Sperm Enzyme Is Essential for Male Fertility
University of North Carolina Health Care System

A study led by scientists at the University of North Carolina at Chapel Hill has determined that a novel enzyme in sperm is essential for sperm motility and male fertility. The new study may offer a potential target for an effective, non-hormonal male contraceptive.

Released: 10-Nov-2004 3:20 PM EST
Significant Improvements in Pelvic Pain, Depression After Hysterectomy
University of North Carolina Health Care System

A study co-authored by researchers from the University of North Carolina at Chapel Hill School of Medicine for the first time has shown significant improvements in self-reported pelvic pain and depression after hysterectomy.

Released: 5-Nov-2004 2:50 PM EST
New Brain Cells Develop During Alcohol Abstinence
University of North Carolina Health Care System

University of North Carolina at Chapel Hill scientists have reported "“ for the first time "“ a burst in new brain cell development during abstinence from chronic alcohol consumption.

Released: 4-Nov-2004 2:50 PM EST
Lineberger Researchers Identify Molecular Markers of Aging
University of North Carolina Health Care System

Researchers at the University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center may have made a crucial discovery in the understanding of cellular aging.

Released: 8-Oct-2004 3:50 PM EDT
Basic Mechanism in Cell Growth Control Involving Damaged DNA
University of North Carolina Health Care System

Scientists at the University of North Carolina at Chapel Hill School of Medicine and the UNC Lineberger Comprehensive Cancer Center describe - for the first time - how some proteins interact to ensure that the cell does not continually divide when its DNA is damaged.

Released: 10-Sep-2004 3:40 PM EDT
New Dye Directly Reveals Activated Proteins in Living Cells
University of North Carolina Health Care System

A series of experiments shows for the first time that novel biosensor dyes can directly reveal activation of proteins in individual living cells.

Released: 12-Aug-2004 4:10 PM EDT
Gene Changes Linked to Eye Pressure: Implications for Glaucoma Therapy
University of North Carolina Health Care System

Scientists have discovered that increased pressure within the eye alters a set of genes normally involved in preventing hardening of tissue. The new findings may have implications for glaucoma therapy.

Released: 29-Jul-2004 4:40 PM EDT
Surprising 'Remodeling' Property of Gene Regulation Process
University of North Carolina Health Care System

Much like moving furniture around to create more space, cells dramatically rearrange their entire genome in order to allow the right genes to be turned on at the right time.

Released: 28-Jul-2004 4:50 PM EDT
Researchers Awarded $8.65 Million from National Institute on Aging
University of North Carolina Health Care System

A team of scientists at the School of Medicine has been awarded a federal grant of $8.65 million to investigate the molecular basis of blood vessel aging and its role in the development of vascular disease, including heart attack.

Released: 9-Jul-2004 6:20 AM EDT
Residency's Influence in Doctors' Decisions to Use Smoking Cessation Methods
University of North Carolina Health Care System

Primary-care doctors who use smoking cessation methods while training as residents are twice as likely to continue doing so in their medical practice more than eight years later, new research at the University of North Carolina at Chapel Hill shows.

Released: 7-Jul-2004 6:20 AM EDT
Research Accelerates Discovery of Novel Gene Function
University of North Carolina Health Care System

University of North Carolina at Chapel Hill researchers have developed a new technique for rapidly identifying the functions of genes. The "high throughput" technique can be used in both cell culture and in animal models to screen thousands of genes for a particular biological function.

Released: 1-Jul-2004 4:10 PM EDT
National Parkinson Foundation Names UNC as 'Center of Excellence'
University of North Carolina Health Care System

The National Parkinson Foundation has designated UNC as an NPF Center of Excellence. With this accolade, the UNC School of Medicine and UNC Hospitals became the first medical center in North Carolina to join the ranks of only 42 NPF Centers of Excellence worldwide.

Released: 30-Jun-2004 6:00 PM EDT
Scientists Discover Molecular Pathway to Nerve Growth, Regeneration
University of North Carolina Health Care System

Scientists have discovered key steps involved in regulating nerve growth and regeneration that may have implications for spinal cord research.



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