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By studying the genetic makeup of breast cancer patients, doctors are taking the next steps forward in delivering more personalized care to patients. Whole genome sequencing from cancers is not a new concept, but recently researchers have delved more deeply into the evolution of breast cancers identifying that it comes in four distinct types. Breaking down how the cells of each sub-type of the disease function is allowing for doctors to customize treatments for improved outcomes.

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In a new paper published early online by the Annals of Surgery, physician-researchers at University Hospitals Case Medical Center describe a new tool called the HARM score that reliably measures quality and clinical outcomes for colon and rectal surgery patients. The name of the tool reflects the data sources used to calculate the score: HospitAl stay, Readmission rate, and Mortality. The paper demonstrates a strong correlation between the HARM score, and the quality of clinical outcomes achieved by surgeons and hospitals for patients having major abdominal surgery.

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University Hospitals Seidman Cancer Center breaks ground today on a $30 million center for proton therapy, an advanced type of radiation treatment that uses a powerful beam of protons to precisely target a tumor and at the same time reduce radiation to uninvolved tissues. There are currently only 11 operational proton therapy centers in the nation, and this will will be the first in Ohio. First patients will be in 2015.

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Researchers publish findings that a new form of imaging – PET/MRI – is promising for several types of cancer. Article is titled “PET/MRI: Applications in Clinical Imaging,” and is published in the September issue of Current Radiology Reports.

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In a first-of-its-kind clinical trial, physician-scientists at University Hospitals Case Medical Center found that sleep quality impacts skin function and aging. The study, commissioned by Estée Lauder, demonstrated that poor sleepers had increased signs of skin aging and slower recovery from a variety of environmental stressors, such as disruption of the skin barrier or ultraviolet (UV) radiation. Poor sleepers also had worse assessment of their own skin and facial appearance.

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After an extensive national search, Case Western Reserve University School of Medicine and University Hospitals Case Medical Center have named Douglas Rhee, MD, an accomplished glaucoma specialist, eye surgeon and researcher, chair of the Department of Ophthalmology and Visual Sciences.

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Case Western Reserve University has signed an exclusive worldwide licensing agreement granting University Hospitals (UH) Case Medical Center rights to a series of diagnostic tests to determine drug resistance and co-receptor tropism in human immunodeficiency virus (HIV).

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University Hospitals Eye Institute will be one of the first medical centers in the United States to offer the Argus® II Retinal Prosthesis System (“Argus II”).

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University Hospitals Case Medical Center clinical researchers have launched an innovative clinical trial, unique in its design, which will evaluate the ability of a patient’s own stem cells to prevent leg amputations in end stage peripheral arterial disease (PAD).

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Physicians at University Hospitals Case Medical Center enrolled their first patients in the ROADSTER Study, a global, multicenter clinical trial evaluating a novel, less-invasive procedure to help clear blockages in carotid arteries and prevent strokes.

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Researchers from University Hospitals Case Medical Center’s (UHCMC) Seidman Cancer Center will present findings from two studies evaluating new technologies designed to address common barriers to patient enrollment in clinical trials. Results from a large-scale, randomized trial demonstrated that the use of tailored, web-based videos delivering educational information to patients before an oncologist visit can significantly improve knowledge and reduce attitudinal barriers that impact enrollment in clinical trials. A second, preliminary study showed that a new automated technology created by UHCMC researchers helped oncologists identify clinical trials for individual patients in a busy outpatient oncology clinic.

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A cancer patient at the Ireland Cancer Center at University Hospitals of Cleveland is the first person in the world to be treated with a new class of drugs that targets and destroys cancer-feeding blood vessels.

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To meet the special needs of both adoptive parents and their children, Rainbow Babies and Childrens Hospital has developed a new program called the Rainbow Center for International ChildHealth. Children who are adopted from overseas sometimes carry rare diseases, or have psychological or behavioral problems associated with neglect or deprivation common to institutionalization.