Vaccine Treatment for Advanced Breast Cancer
University of North Carolina Health Care SystemDoctors at the University of North Carolina have opened their first clinical trial of a vaccine treatment for advanced breast cancer.
Doctors at the University of North Carolina have opened their first clinical trial of a vaccine treatment for advanced breast cancer.
HIV, the virus that causes AIDS, may be adapted for use in gene therapy to treat genetic diseases and disorders of the immune system, even including AIDS, according to a scientist at the University of North Carolina at Chapel Hill.
In research carrying implications for human disease development, University of North Carolina scientists and others have linked gene defects to the inability of cells to repair damaged DNA (Cell, 4-13-00).
The effects of antidepressant drugs on the heart's response to stress will be looked at by a University of North Carolina at Chapel Hill study.
The University of North Carolina at Chapel Hill Division of Health Affairs, comprised of top-10 ranked schools of dentistry, medicine, nursing, pharmacy and public health, has created a media fellowship to address the issue of aging.
Women with a very severe form of premenstrual syndrome are more sensitive to pain and are more likely to have lower blood levels of beta-endorphins, according to University of North Carolina at Chapel Hill researchers.
The discovery by University of North Carolina scientists of a distinct family of proteins that bind to human sperm may offer important new clues to male fertility and possible male contraception (Endocrinology, 3-00).
A brain steroid called allopregnanolone is likely an important mediator of alcohol's well-known effects on anxiety and sedation, report University of North Carolina School of Medicine scientists (Journal of Neuroscience, 3-00).
Pregnant women with HIV may reduce the risk of transmitting the AIDS virus to their babies by taking a combination of AIDS drugs and giving birth by cesarean section, according to University of North Carolina researchers.
AIDS patients may be at significantly greater risk of death when cytomegalovirus (CMV) circulates in their blood, suggests research at the University of North Carolina.
A study, led by a University of North Carolina scientist, that focuses on the complex network of biochemical signals between proteins and enzymes sheds new light on the process of cell growth regulation (Nature, 1-20-00).
A distinguished scientist at the University of North Carolina has endowed a $10,000 national prize to be awarded annually for an outstanding scientific contribution to neuroscience.
Cooperation rather than competition may signal a new era of federally funded research for the nation's top scientists who develop and study mouse models of cancer.
A study led by scientists at the University of North Carolina at Chapel Hill points to a group of lipids (fats) that are crucial to proper formation of the myelin sheath surrounding nerve fibers. The findings add important new knowledge to the molecular biology of myelin and diseases of myelin loss.
Evidence for a possible gene on chromosome 13 that causes autism is reported by researchers at the University of North Carolina at Chapel Hill and collaborating institutions.
A new study at the University of North Carolina at Chapel Hill is the first to establish that a mutation in a gene associated with about 20 percent of all cases of hereditary deafness found in Whites is also found in Blacks.
The University of North Carolina at Chapel Hill has won a $42.1 million federal contract to determine the effectiveness and safety of a new class of anti-psychotic drugs for people with schizophrenia and those with behaviors associated with Alzheimer's disease.
A study at the University of North Carolina at Chapel Hill may have identified a new way to halt herpes simplex virus in its molecular tracks.
University of North Carolina at Chapel Hill researchers are studying the value of a new biomarker for improving cervical cancer screening. The clinical trial will examine cervical smears for telomerase, a protein released into cells when chromosomes shorten, stick together and become genetically unstable
New research at the University of North Carolina at Chapel Hill suggests that adhesions following gynecologic and abdominal surgery can be prevented by applying a special antibody solution at the end of the operation.
A program of telephone counseling and education by nurses helps cancer patients cope with the effects of their disease, according to studies at the University of North Carolina at Chapel Hill.
A study of fruit flies by scientists at the University of North Carolina at Chapel Hill may yield new clues to human colon cancer development.
Scientists at the University of North Carolina at Chapel Hill have won a five-year federal grant totaling more than $12 million to develop a safe and effective vaccine against HIV, the virus that causes AIDS.
A study at the University of North Carolina at Chapel Hill has identified a novel molecular mechanism in cell proliferation. The study shows that a molecular switch has a pivotal role in the regulation of cell growth and death.
Scientists at the University of North Carolina at Chapel Hill have used injections of protein fragments to prevent the development of type-I diabetes in a strain of mice that develop the disease.
A genetic variant of HIV that is tied to more rapid disease progression in the United States and Europe is rare in Africa, according to a new study headed by researchers at the University of North Carolina at Chapel Hill.
Gene mutations tied to inherited diseases may cause only a portion of the expected disorder, according to scientists at the University of North Carolina at Chapel Hill. Implications are important for genetic screening and molecular diagnostics.
Physicians at the University of North Carolina at Chapel Hill are testing a new, less invasive method for repairing abdominal aortic aneurysms, potentially dangerous defects of the body's major artery found often in the elderly.
Scientific evidence points to a possible link between schizophrenia and altered brain development in the first three months of pregnancy, according to a new report from the University of North Carolina at Chapel Hill.
Researchers at the University of North Carolina at Chapel Hill have found that responses to stress during early adulthood could help predict one's risk for high blood pressure 10 years later.
Symptoms of major depression are most likely to persist in people who also have an anxiety disorder, according to a study headed by a psychiatrist at the University of North Carolina at Chapel Hill.
New results from gene therapy studies at the University of North Carolina at Chapel Hill may lead to an effective long-term treatment, if not a cure, for hemophilia A, the most common form of this inherited blood disease.
Married people who receive a high level of social support from their family -- especially from their spouse -- show better heart and blood pressure responses to stress than couples whose family support level is low.
Researchers at the University of North Carolina at Chapel Hill have shown that men infected with HIV will more rapidly develop AIDS as stressful events accumulate in their lives or if their social supports are weak.
The molecular role in cancer development of a mutated tumor suppressor gene known as ARF has been discovered by University of North Carolina at Chapel Hill scientists. The new findings help clarify why ARF is the second most frequently mutated gene in human cancers.
The co-directors of the UNC Center for Functional Gastrointestinal and Motility Disorders are senior authors of three scientific reports on Irritable Bowel Syndrome (IBS), slated for presentation at this year's American Gastroenterology Society Digestive Diseases Week meetings, May 16-19 in Orlando, Fla
The demand for the new sentinel lymph node biopsy has prompted a surge in requests from community-based surgeons for lessons in the technique.
Scientists at the University of North Carolina at Chapel Hill have discovered three genes crucial to the survival of cells, they reported in the April 23 issue of the journal Molecular Cell. The genes select cellular proteins for the disposal and eventual recycling of their components.
Clinical trials are now underway at the University of North Carolina at Chapel Hill on a promising new drug in the fight against malignant and recurrent brain tumors that have so far proved very difficult to treat.
Women with a history of sexual and physical abuse are more likely to have poor health during pregnancy and after childbirth, according to a study at the University of North Carolina at Chapel Hill.
New research at the University of North Carolina at Chapel Hill ties estrogen replacement to reducing blood pressure in older women with hypertension.
A new study at the University of North Carolina at Chapel Hill links increased levels of the hormone oxytocin to lower blood pressure among mothers who nurse their babies. The findings help explain why many breast-feeding mothers report feeling mellow and relaxed after nursing.
A study by researchers at the University of North Carolina at Chapel Hill has identified molecular changes in nerve cells that may play an important role in an abnormal pain syndrome -- causalgia -- which often eludes effective treatment.
In a medical first for North Carolina, pediatric surgeons at the University of North Carolina at Chapel Hill have corrected a common chest-wall deformity called "funnel chest" by using a new, simpler operation.
In a study of life's beginnings, scientists at the University of North Carolina at Chapel Hill have moved a step closer to unraveling the biochemical mystery of embryogenesis, the process by which an egg cell transforms into an embryo.
AIDS investigators at the University of North Carolina at Chapel Hill are testing the first of a new class of drugs that attacks HIV before it enters the cell and may prove effective for patients with drug-resistant HIV.
An associate professor of social medicine and history at the University of North Carolina at Chapel Hill, has been named one of 10 international recipients of a $1 million James S. McDonnell Centennial Fellowship.
A gene therapy clinical trial for Fanconi anemia, a fatal inherited blood disease, is set to begin at the University of North Carolina at Chapel Hill.
Molecular doorways on the surface of cells may be important factors in the success or failure of human gene therapy using altered viruses, according to researchers at the University of North Carolina at Chapel Hill, who reported their study Jan. 4 in the journal Nature Medicine.
Researchers at the University of North Carolina at Chapel Hill confirmed the safety of digoxin, one of the oldest and most frequently prescribed medicines and the most common digitalis drug for heart failure, in the December 7-21 issue of the Archives of Internal Medicine.