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A team of researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) has discovered that a transcription factor, TOX2, was aberrantly increased in patients with Natural killer/T-cell lymphoma (NKTL). The increased TOX2 level leads to the growth and spread of NKTL, as well as the overproduction of PRL-3 – an oncogenic phosphatase that is a known key player in the survival and metastasis of several other types of cancers. This breakthrough discovery presents a potential novel therapeutic target to treat NKTL.

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A community study involving 101 participants aged between 38 to 91 years old has found that weekly 10-min exposure to very low levels of pulsed electromagnetic field using the BIXEPS device developed by researchers from the National University of Singapore significantly improves mobility, especially in the elderly. This painless therapy produces comparable results to exercise, and also improves body composition and reduces pain

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Batteries play a crucial role in powering many modern devices, such as mobile phones, pacemakers, and electric vehicles. Yet, traditional lithium-ion batteries pose limitations such as safety risks, short life cycles, and long charging times. The pioneer niobium-graphene batteries developed by the Centre for Advanced 2D Materials (CA2DM) at the National University of Singapore (NUS), an innovator in the research of graphene and other 2-dimensional (2D) materials, and CBMM, the global leader in niobium products and technology, will address all these problems. The batteries are being tested at the new CBMM-CA2DM Advanced Battery Laboratory which was launched today by NUS and CBMM and established with a joint investment of USD3.8 million (S$5 million) over three years, supported by the National Research Foundation, Singapore.

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A research team from the National University of Singapore (NUS) Faculty of Science, led by Professor Liu Xiaogang from the Department of Chemistry, has developed a 3D imaging sensor that has an extremely high angular resolution, which is the capacity of an optical instrument to distinguish points of an object separated by a small angular distance. This allows the novel sensor to capture 3D images at higher depth resolution.

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A research team from the National University of Singapore (NUS) has successfully used common plant proteins to 3D-print an edible cell culture scaffold, allowing more affordable and sustainable lab-grown meat to be served on the table.

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A microsatellite for maritime communications developed by the Satellite Technology And Research Centre (STAR) under the National University of Singapore’s College of Design and Engineering (NUS CDE), and A*STAR’s Institute for Infocomm Research (I2R), has been successfully launched from the Satish Dhawan Space Centre in Sriharikotta, India, on 22 April 2023, at 4.50pm (Singapore time). The microsatellite – Lumelite-4 - will test the VDES technology for potential maritime applications, such as real-time maritime traffic and asset tracking for better predictive analysis, as well as secured and reliable ship-to-ship or ship-to-port communication for enhanced navigational safety and port efficiencies.

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Gastric cancer is one of the most common cancers worldwide. A new invention by NUS researchers could help improve the treatment of this cancer by enhancing the precision of radiotherapy, which is commonly used in combination with treatment options such as surgery, chemotherapy or immunotherapy.

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Researchers from the National University of Singapore have discovered a new single-element ferroelectric material that alters the current understanding of conventional ferroelectric materials and has future applications in data storage devices.

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A team of researchers from the College of Design and Engineering at the National University of Singapore, led by Professor Ho Ghim Wei from the Department of Electrical and Computer Engineering, has developed a revolutionary technique for producing ultrathin inorganic membranes.

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Researchers worldwide are actively investigating safer alternatives for the storage of natural gas—solidified natural gas (SNG), or natural gas hydrates, may just be the answer. These gas hydrates, however, are currently limited to the small scale of bench-top laboratory experiments. To that end, Professor Praveen Linga from the Department of Chemical and Biomolecular Engineering at the College of Design and Engineering, National University of Singapore, is working on advancing SNG technology for industrial viability.

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Slips, trips and falls (STFs) remain the top causes of major injuries in the workplace. Harnessing the power of research and technology to boost workplace safety, Professor Lim Chwee Teck from the National University of Singapore’s (NUS) Department of Biomedical Engineering, which is under the College of Design and Engineering, as well as Institute for Health Innovation & Technology (iHealthtech), collaborated with NUS start-up, FlexoSense, to develop a smart insole which can track workplace STFs in real time and is the first of its kind that can detect a person’s balance.

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A team of researchers from the Cancer Science Institute of Singapore at the National University of Singapore has breathed new life into an existing drug — combatting a type of blood cancer called T-cell acute lymphoblastic leukaemia, or T-ALL. The drug, called PIK-75, was initially discovered over a decade ago but was dismissed in favour of newer ones. Now, it has made a comeback that deems it unmissable — the researchers established that the drug could block not just one but two crucial cancer-causing pathways of T-ALL, enabling them to develop new treatments that could effectively stem the disease.

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A team of scientists from the National University of Singapore Tropical Marine Science Institute has developed a dolphin-inspired compact sonar with a novel echo processing method that allows for clearer visual imaging underwater compared to the conventional signal processing method of visualising sound echoes.

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A recent study by researchers from the NUS Yong Loo Lin School of Medicine and the Memory, Ageing and Cognition Centre under the National University Health System revealed that low levels of ergothioneine in blood plasma may predict an increased risk of cognitive impairment and dementia, suggesting possible therapeutic or early screening measures for cognitive impairment and dementia in the elderly.

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A global deal to protect nature and the benefits it provides to people will be negotiated during the United Nations COP15 biodiversity conference in Montreal, with a key target of the new biodiversity framework calling for at least 30 per cent of global land and sea areas to be conserved by 2030.

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Scientists from the National University of Singapore have discovered a novel low-cost method of testing for cancers. Called the Heatrich-BS assay, this new test sequences clinical samples that have been heated in order to isolate cancer-specific signatures found in a patient’s blood.

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A team of scientists from the National University of Singapore (NUS) has successfully identified the urinary biomarkers of an emerging subclass of synthetic cannabinoids, called OXIZID, to monitor potential abuse.

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The Darwin Online project at the National University of Singapore (NUS) released an exceptional manuscript handwritten by Charles Darwin in 1865. The manuscript has been placed on auction at Sotheby’s auction house in New York City, making international news. To understand this unique document, historian of science Dr John van Wyhe from the NUS Department of Biological Sciences, and founder and Director of Darwin Online, sheds light on the origins of the 157-year old manuscript, and why Darwin chose to handwrite the selected passage from Origin of Species.

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A team of researchers from the National University of Singapore have made a serendipitous scientific discovery that could potentially revolutionise the way water is broken down to release hydrogen gas - an element crucial to many industrial processes.

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Marine science is vital to the health and vitality of the regional seas around Singapore, which supports the nation’s survival and success.