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Released: 25-Aug-2003 5:00 PM EDT
Existing Anti-Inflammatory Drug Could Help Children Suffering from an Inherited Bone Disease
UT Southwestern Medical Center

A drug commonly used as an anti-inflammatory medication could also help children with an inherited form of rickets avoid complications from their disease, according to researchers.

Released: 19-Aug-2003 5:00 PM EDT
Obese Individuals May be More Susceptible to Altitude Sickness
UT Southwestern Medical Center

Obese individuals traveling to a high-altitude destination should take extra precautions, according to researchers.

Released: 15-Aug-2003 1:00 AM EDT
Researchers Identify Second Gene Responsible for Rare Syndrome Associated with Skeletal Defects
UT Southwestern Medical Center

Researchers have discovered a second gene responsible for a rare syndrome that causes the loss of bone from the lower jaw, fingers, toes and collarbone.

8-Aug-2003 4:00 PM EDT
Faster Method for Creating Antibodies in Mice Discovered
UT Southwestern Medical Center

Researchers have discovered a system to create antibodies in mice up to 10 times faster than previous laboratory techniques allowed.

7-Aug-2003 2:00 PM EDT
Main Regulator of Membrane Trafficking Not What Researchers Once Thought
UT Southwestern Medical Center

Researchers have identified a main regulator of the system that controls membrane trafficking, debunking what scientists for a decade had thought controlled this process.

29-Jul-2003 10:00 AM EDT
Report All Adverse Effects from New Drugs to Curtail Liver Injuries
UT Southwestern Medical Center

Physicians and pharmacists should be more proactive in reporting adverse drug reactions that result in liver damage after medications are approved by the FDA, writes a researcher.

Released: 30-Jul-2003 12:00 AM EDT
HAART Therapy Significantly Prolongs Survival In AIDS Patients Diagnosed with Central Nervous System Lymphoma
UT Southwestern Medical Center

AIDS patients with primary central nervous system lymphoma who receive the HAART "cocktail" therapy live much longer than those not treated with the therapy, researchers found.

25-Jul-2003 6:00 PM EDT
Protein Can Predict Progression of Most Common Childhood Brain Tumor
UT Southwestern Medical Center

Researchers have discovered that the presence of a particular protein can predict whether the most common childhood brain tumor will continue to grow or return following surgery.

25-Jul-2003 6:00 PM EDT
Researchers Discover Method of Postponing Labor in Mice
UT Southwestern Medical Center

Researchers have discovered a way to inhibit a biochemical process that accompanies labor and to postpone delivery for one to two days in pregnant mice.

16-Jul-2003 12:00 AM EDT
Link Between Neuronal Calcium Channel, Mutated Gene That Causes Huntington’s Disease
UT Southwestern Medical Center

Abnormally high calcium levels spurred on by a mutated gene may lead to the death of neurons associated with Huntington's disease, an inherited genetic disorder, characterized by mental and physical deterioration, for which there is no known cure.

Released: 16-Jul-2003 12:00 AM EDT
Tumor-Suppressor Gene in Fruit Flies That Controls Cell Production, Death
UT Southwestern Medical Center

UT Southwestern Medical Center at Dallas researchers have discovered a tumor-suppressor gene that, in fruit flies, simultaneously restricts cell proliferation and promotes cell death, a process that may also play an important role in the genesis of cancer in humans.

Released: 14-Jul-2003 12:00 AM EDT
Regions of Human Genes Highly Prone to Mutation
UT Southwestern Medical Center

UT Southwestern Medical Center at Dallas researchers have taken the first step in defining the sites in human genes most prone to mutation, which eventually could lead to discovery of the genetic bases of many human diseases.

7-Jul-2003 12:00 AM EDT
Gene Mutations Responsible for Congenital Heart Defects
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas have discovered a gene critical to the development of the human heart and that mutations in the gene lead to congenital heart defects -- the leading noninfectious cause of death in newborns.

4-Jul-2003 12:00 AM EDT
Gene Impacts Operation of Body's Internal Clock
UT Southwestern Medical Center

Removing a gene that helps control the body's internal clock dramatically changes patterns of sleep, activity and feeding in mice, researchers have discovered.

1-Jul-2003 12:00 AM EDT
Cross Talk Between Bacteria, Host Leads to E. Coli Infection
UT Southwestern Medical Center

A strain of E. coli that causes severe, sometimes deadly, intestinal problems relies on signals from beneficial human bacteria and a stress hormone to infect human cells, a researcher at UT Southwestern Medical Center at Dallas has discovered.

Released: 26-Jun-2003 12:00 AM EDT
Role Cell Surface Proteins Play in Brain Function
UT Southwestern Medical Center

A specific group of brain proteins is essential to activate communication between neurons, and without this group of proteins all functions of the central nervous system are disrupted, researchers at UT Southwestern Medical Center at Dallas have discovered.

Released: 25-Jun-2003 12:00 AM EDT
"Sleep Docs" Learn to Treat Patients with Slumber Problems
UT Southwestern Medical Center

People know to contact a doctor when they're sick or injured. But if they can't sleep, they may benefit by waking up to a new specialty at UT Southwestern Medical Center at Dallas and contacting a sleep doctor.

25-Jun-2003 12:00 AM EDT
Development of Prostate Drug
UT Southwestern Medical Center

A new finding revealing that the drug finasteride reduces the risk of prostate cancer by nearly 25 percent represents the culmination of three decades of research that began in the early 1970s at UT Southwestern Medical Center.

Released: 17-Jun-2003 12:00 AM EDT
Inherited Gene and Post-Traumatic Injury Seizures
UT Southwestern Medical Center

People who inherit a particular gene involved in lipid metabolism in the brain appear to be at higher risk of developing seizures after traumatic brain injury, according to researchers at UT Southwestern Medical Center at Dallas.

10-Jun-2003 12:00 AM EDT
Stages Used by Immune System Cells to Eliminate Viral Infections, Cancer Cells
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas have partially uncovered the stages in the elimination of viral infections and cancer cells by the human immune system, a finding that may lead to better treatments for certain cancers.

Released: 3-Jun-2003 12:00 AM EDT
Fatty-Acid Oxidation, Nutrient Source in Placenta
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas have helped discover that an expectant mother's placenta nourishes her fetus by oxidizing fatty acids in addition to providing the developing fetus with glucose -- previously believed to be the placenta's only energy source.

20-May-2003 12:00 AM EDT
New Cause for Incurable Muscle Condition Identified
UT Southwestern Medical Center

Researchers from UT Southwestern Medical Center at Dallas and the Mayo Clinic have discovered a novel genetic mutation that leads to a debilitating muscle condition known as myasthenia.

Released: 7-May-2003 12:00 AM EDT
Insulin-Degrading Enzyme May Affect Risk of Alzheimer's Disease
UT Southwestern Medical Center

Low levels of an enzyme that degrades insulin could increase the risk for Alzheimer's disease, according to a new study in mice by doctors at UT Southwestern Medical Center at Dallas.

Released: 1-May-2003 12:00 AM EDT
Researchers, Nobel Prize Winners Share Prize
UT Southwestern Medical Center

Dr. Michael S. Brown and Dr. Joseph L. Goldstein, whose groundbreaking studies have led to the development of lifesaving, cholesterol-lowering statin drugs used by millions of people worldwide, have been named co-recipients of the $500,000 Albany Medical Center Prize in Medicine and Biomedical Research.

Released: 24-Apr-2003 12:00 AM EDT
Organized Sports among Safest Outdoor Activities for Kids
UT Southwestern Medical Center

Participating in organized sports is one of the safest outdoor activities for children, say physicians at UT Southwestern Medical Center at Dallas.

22-Apr-2003 12:00 AM EDT
Cholesterol-Lowering Drugs Shown to Decrease Predictor of Alzheimer's Disease
UT Southwestern Medical Center

Cholesterol-lowering medications known as statins also play an important role in reducing levels of a strong predictor of Alzheimer's disease, according to a new study from UT Southwestern Medical Center at Dallas researchers.

Released: 18-Apr-2003 12:00 AM EDT
1-Year-Old Twins to Have Cochlear Implants Turned On
UT Southwestern Medical Center

One-year-old twin brothers Hunter and Haydn Corker of West Texas have all sorts of similarities like blond hair, sparkling blue eyes and infectious laughs. They also have profound hearing loss.

18-Apr-2003 12:00 AM EDT
Drugs Restore Immune Response Blocked by Hepatitis C Virus in Human Cells
UT Southwestern Medical Center

A new generation of drugs restores the immune response blocked by the hepatitis C virus, reducing the virus to nearly undetectable levels in a matter of days, according to researchers at UT Southwestern Medical Center at Dallas and UT Medical Branch at Galveston.

16-Apr-2003 12:00 AM EDT
Estrogen Patch Compared to Pill Minimizes Cardiovascular Risk Factor
UT Southwestern Medical Center

Administering estrogen replacement therapy via a skin patch rather than a pill minimizes a cardiovascular risk factor in postmenopausal women, according to researchers at UT Southwestern Medical Center at Dallas.

13-Apr-2003 12:00 AM EDT
Combination Drug Therapy Reduces Risk Factors of Coronary Heart Disease
UT Southwestern Medical Center

Combining two lipid-lowering medications safely and effectively reduces multiple coronary heart disease risk factors, according to UT Southwestern Medical Center at Dallas researchers.

11-Apr-2003 12:00 AM EDT
Protein Mechanism for Potential Atherosclerosis Development
UT Southwestern Medical Center

Inactivating a protein that helps regulate the proliferation of vascular cells increases the chance of developing atherosclerosis, a major cause of heart disease, researchers at UT Southwestern Medical Center at Dallas have discovered.

1-Apr-2003 12:00 AM EST
Defect of Cilia-Assembly Protein, Genetic Cause of Kidney Failure
UT Southwestern Medical Center

A protein responsible for the assembly of cell cilia -- the hair-like projections from cells -- may cause polycystic kidney disease, the most common genetic cause of kidney failure, according to a new study at UT Southwestern Medical Center at Dallas.

Released: 26-Mar-2003 12:00 AM EST
April 2003 Health News Tips
UT Southwestern Medical Center

Get tips on how to talk honestly to children about war, the realtionship between weight loss and breakfast, making the most of sunscreen, fighting heartburn with gum and getting a jump on diagnosing rheumatoid arthritis.

18-Mar-2003 12:00 AM EST
Monkey Species that Fights off AIDS May Lead to New Human Treatments
UT Southwestern Medical Center

A deactivation of the immune system in patients infected with HIV could be one way to inhibit progression to the immunodeficiency diseases associated with AIDS, researchers from UT Southwestern Medical Center at Dallas and Emory University report.

Released: 5-Mar-2003 12:00 AM EST
March 2003 Health News Tips
UT Southwestern Medical Center

March 2003 Health News Tips from UT Southwestern Medical Center at Dallas, including information on eye strain, anxiety, heart attacks, West Nile virus and kidney stones.

Released: 4-Mar-2003 12:00 AM EST
Relevant, Reader-Friendly Story Ideas with Experts
UT Southwestern Medical Center

1) allergy meds not for colds, 2) water amoeba and contact lenses, 3) watch out for ticks, 4) staying safe in electrical storms, 5) treating the ears after leaving the water, and others.

Released: 1-Mar-2003 12:00 AM EST
Leukemia Drug May Not Treat Certain Forms of Disease
UT Southwestern Medical Center

A drug used to treat a rare form of leukemia may not fight the same disease in the central nervous system, according to researchers at UT Southwestern Medical Center at Dallas.

Released: 20-Feb-2003 12:00 AM EST
Parkinson's Drug Linked to Heart Disease Risk Factor
UT Southwestern Medical Center

A drug used for the last 40 years to treat Parkinson's disease increases blood levels of an amino acid that could put patients at increased risk for heart disease, according to researchers at UT Southwestern Medical Center at Dallas.

Released: 18-Feb-2003 12:00 AM EST
New Laser Vision Corrective Surgery
UT Southwestern Medical Center

Ophthalmologists at UT Southwestern Medical Center at Dallas have begun using the newest technology in laser eye surgery, which promises to give patients better vision than traditional laser surgeries and make more people candidates for procedures.

Released: 6-Feb-2003 12:00 AM EST
Criteria for Safe, Rapid Treatment of Cocaine-Related Chest Pain
UT Southwestern Medical Center

Close observation and testing of patients with cocaine-related chest pain in the first 12 hours after diagnosis is sufficient to safely determine the risk of heart complications, according to a researcher at UT Southwestern Medical Center at Dallas.

Released: 4-Feb-2003 12:00 AM EST
Procedures to Make Bone-Marrow Transplants Safer
UT Southwestern Medical Center

Researchers at UT Southwestern Medical Center at Dallas are helping develop new procedures that may reduce infections and diseases resulting from bone-marrow transplants.

Released: 4-Feb-2003 12:00 AM EST
$10 Million Solomon Gift Endows General Medicine Division
UT Southwestern Medical Center

UT Southwestern Medical Center at Dallas will use a $10 million gift from Mr. and Mrs. William T. Solomon to help develop a model for clinical service in general internal medicine, enabling physicians and staff to center their attention on patients in a time when health care has become increasingly impersonal and perplexing.

25-Jan-2003 12:00 AM EST
Gene That Could Have Important Role in Human Wasting Disorder Identified
UT Southwestern Medical Center

A gene regulating muscle formation in fruit flies could play an important role in a wasting disorder in humans, researchers at UT Southwestern Medical Center at Dallas have discovered.

Released: 14-Jan-2003 12:00 AM EST
New Model for Understanding Obesity, Diabetes
UT Southwestern Medical Center

Through the study of fat storage in nematode worms, researchers at UT Southwestern Medical Center at Dallas have formulated a new model for understanding the mechanisms of obesity and diabetes in humans.

Released: 3-Jan-2003 12:00 AM EST
Angioplasty More Effective than Clot Busters in Treating Heart Attack
UT Southwestern Medical Center

Angioplasty offers a better prognosis than clot-dissolving medications for treating patients with the deadliest type of heart attack, report researchers at UT Southwestern Medical Center at Dallas.

Released: 3-Jan-2003 12:00 AM EST
Cobb Named Dean of Graduate School of Biomedical Sciences
UT Southwestern Medical Center

Dr. Melanie H. Cobb, professor of pharmacology at UT Southwestern Medical Center at Dallas, has been named dean of Southwestern Graduate School of Biomedical Sciences, effective Jan.1.

Released: 31-Dec-2002 12:00 AM EST
Former Astronaut to Join UT Southwestern's Biotech Effort
UT Southwestern Medical Center

Dr. Mary Ellen Weber -- former NASA astronaut, instrument-rated pilot, world-class skydiver and recent MBA graduate -- has been named associate vice president for commerce and public policy at UT Southwestern Medical Center at Dallas.

Released: 20-Dec-2002 12:00 AM EST
Gene Responsible for Hereditary Nerve Disease Linked to Cardiovascular Problems
UT Southwestern Medical Center

While studying a gene that can cause tumors in the nervous system, UT Southwestern Medical Center at Dallas researchers found the gene's absence in certain blood vessel cells also can trigger cardiovascular problems such as hypertension and congenital heart disease.

Released: 19-Dec-2002 12:00 AM EST
More Dialysis, Highly Permeable Artificial Kidney May Not Aid Some
UT Southwestern Medical Center

Longer dialysis treatment and use of a highly permeable artificial kidney may not improve survival rates or reduce hospitalization of patients with end-stage kidney disease, a researcher at UT Southwestern Medical Center at Dallas has discovered.

Released: 17-Dec-2002 12:00 AM EST
Overdoses of Acetaminophen Cause Most Cases of Acute Liver Failure
UT Southwestern Medical Center

Unintentional acetaminophen overdose is the most common cause of acute liver failure in the United States, research from UT Southwestern Medical Center at Dallas shows.



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