A primary care program promoting the health of older adults was well received by family medical practices but lacked clinical benefits, says a study led by McMaster University researchers, published in the Annals of Family Medicine.
Tobacco users in Canada are exposed to higher levels of cyanide than smokers in lower-income nations, according to a large-scale population health study from McMaster University.
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The trial, which concluded in 2021, found that 133 hemophilia patients treated weekly with injections of efanesoctocog alfafor a year improved their outcomes and quality of life compared to their previous treatment.
After eight years of work by more than 150 McMaster students and alumni, the NEUDOSE satellite is ready for liftoff.
Scientists who study the origins and evolution of the plague have examined hundreds of ancient human teeth from Denmark, seeking to address longstanding questions about its arrival, persistence and spread within Scandinavia.
Evolutionary geneticists and forensic experts who have spent years analyzing the remains of Chilean poet and Nobel laureate Pablo Neruda have added important new information to the case regarding a possible covert assassination.
Changing the tune of hospital medical devices could improve public health, according to researchers at McMaster University and Vanderbilt University. “By simply changing the sounds in medical devices, we can improve the quality of healthcare delivery and even save lives,” said Michael Schutz, co-author and professor of music cognition and percussion at McMaster.
“A potential pathway between obesity and these stressors could be related to weight bias and stigma; there was extensive media coverage highlighting obesity as a potential risk factor for COVID-19 mortality which may have increased weight stigma,” the researchers wrote. The study examined data from nearly 24,000 participants enrolled in the Canadian Longitudinal Study on Aging (CLSA), who were between the ages of 50 and 96 during the first year of the pandemic. The participants completed the CLSA COVID-19 Questionnaire Study, which collected longitudinal data from April to December 2020. The researchers also used data collected before the pandemic to examine if childhood adversity, such as abuse and neglect, was a factor that modified the relationship between obesity and stress.
Researchers tested lambda’s effectiveness using a randomized placebo-controlled trial involving adults with COVID-19 from both Canada and Brazil, who freely volunteered for the study. A total of 931 people received lambda and 1,018 received a placebo. Eighty-three per cent of the trial participants were vaccinated. Researchers ran the lambda trial from June 2021 to March 2022.
Postpartum depression (PPD) affects up to 20% of mothers and birthing parents, yet only 1 in 10 receive evidence-based treatment. Barriers include time limitations, long waitlists, and concerns about stigma and judgment by health care providers.
The study analyzed data from 1,445 participants aged 45 to 85 years from the Canadian Longitudinal Study on Aging. The participants provided blood samples for DNA methylation analysis and completed a self-report questionnaire on ACEs. These experiences include childhood exposure to physical, emotional or sexual abuse, neglect, as well as exposure to parental intimate partner violence or poor parental mental health. The data was analyzed to determine if there was an association between early childhood adversity and accelerated biological aging.
The sport of orienteering, which draws on athleticism, navigational skills and memory, could be useful as an intervention or preventive measure to fight cognitive decline related to dementia, according to new research from McMaster University.
Seeking to better understand more about the origins and movement of bubonic plague, in ancient and contemporary times, researchers at McMaster University, University of Sydney and the University of Melbourne, have completed a painstaking granular examination of hundreds of modern and ancient genome sequences, creating the largest analysis of its kind.
The use of synthetic food dyes such as Allura Red has increased significantly over the last several decades, but there has been little earlier study of these dyes’ effects on gut health. Khan and his team published their findings in Nature Communications. “What we have found is striking and alarming, as this common synthetic food dye is a possible dietary trigger for IBDs. This research is a significant advance in alerting the public on the potential harms of food dyes that we consume daily,” he said.
Researchers have created a powerful new weapon against bacterial contamination and infection by developing a way to spray bacteriophages – harmless viruses that eat bacteria – onto food and other materials to rid them of harmful pathogens.
An international study led by McMaster University researchers and published in The Lancet Global Health has found that influenza vaccines greatly reduce both pneumonia and cardiovascular complications in people with heart failure. An international study led by McMaster University researchers and published in The Lancet Global Health has found that influenza vaccines greatly reduce both pneumonia and cardiovascular complications in people with heart failure. Data gathered during flu season also showed the vaccine helped protect against cardiovascular complications, such as heart attacks and strokes.
Researchers discovered that by blocking the production of an enzyme called DHODH, they were able to halt the growth of MYC gene-amplified medulloblastoma in mouse models, the most aggressive subtype of this cancer.
Five key messages for general and specialist care providers, as well as caregivers, promote best practices for managing atopic dermatitis in infants.
Physicists at McMaster University have identified a natural delivery system which can safely carry potent antibiotics throughout the body to selectively attack and kill bacteria by using red blood cells as a vehicle.
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