Latest News from: Johns Hopkins Medicine

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Newswise: Johns Hopkins Experts Available to Comment on Endometriosis Awareness Month
Released: 8-Mar-2023 11:00 AM EST
Johns Hopkins Experts Available to Comment on Endometriosis Awareness Month
Johns Hopkins Medicine

Endometriosis is a chronic condition affecting up to 10% of women between the ages of 15 and 44 in the United States, according to the U.S. Department of Health and Human Services. The uterus is lined with tissue — the endometrium — which is replenished every menstrual cycle to prepare for a fertilized egg. In people who have endometriosis, this tissue grows outside the uterus, and is commonly found on or around the reproductive organs including the fallopian tubes, ovaries, bladder and cervix.

Newswise: Heart Tissue Heads to Space to Aid Research on Aging and Impact of Long Spaceflights
Released: 7-Mar-2023 11:50 AM EST
Heart Tissue Heads to Space to Aid Research on Aging and Impact of Long Spaceflights
Johns Hopkins Medicine

Johns Hopkins Medicine researchers are collaborating with NASA to send human heart “tissue-on-a-chip” specimens into space as early as March. The project is designed to monitor the tissue for changes in heart muscle cells’ mitochondria (their power supply) and ability to contract in low-gravity conditions.

Newswise: Research Team Creates Statistical Model to Predict Covid-19 Resistance
Released: 22-Feb-2023 2:35 PM EST
Research Team Creates Statistical Model to Predict Covid-19 Resistance
Johns Hopkins Medicine

Researchers from Johns Hopkins Medicine and The Johns Hopkins University have created and preliminarily tested what they believe may be one of the first models for predicting who has the highest probability of being resistant to COVID-19 in spite of exposure to SARS-CoV-2, the virus that causes it.

Newswise: U.S. Study of Intravenous Mistletoe Extract to Treat Advanced Cancer
Released: 22-Feb-2023 10:00 AM EST
U.S. Study of Intravenous Mistletoe Extract to Treat Advanced Cancer
Johns Hopkins Medicine

Researchers at the Johns Hopkins Kimmel Cancer Center completed what is believed to be the first phase I trial of intravenous Helixor M in the U.S. aimed at determining dosing for subsequent clinical trials and to evaluate safety.

Released: 21-Feb-2023 11:55 AM EST
Let's Talk About Eating Disorders
Johns Hopkins Medicine

Eating disorders are behavioral conditions in which normal eating habits become disrupted and rewarded in an unhealthy way. They can affect a person’s physical and mental health, and often happen in combination with other psychiatric conditions such as depression, anxiety or substance use disorder.

Newswise: Researchers Map Mosquito Cells That May Help the Insects Choose Tastiest Humans
Released: 21-Feb-2023 10:00 AM EST
Researchers Map Mosquito Cells That May Help the Insects Choose Tastiest Humans
Johns Hopkins Medicine

In a bid to understand why mosquitoes may be more attracted to one human than another, Johns Hopkins Medicine researchers say they have mapped specialized receptors on the insects’ nerve cells that are able to fine-tune their ability to detect particularly “welcoming” odors in human skin.

Newswise: Media Advisory: Patients and Families Will Share Children’s Center Stories During Mix 106.5’s 34th Annual Radiothon
Released: 20-Feb-2023 9:00 AM EST
Media Advisory: Patients and Families Will Share Children’s Center Stories During Mix 106.5’s 34th Annual Radiothon
Johns Hopkins Medicine

What: Mix 106.5’s 34th Annual Radiothon benefiting Johns Hopkins Children’s Center kicks off this week on Thursday, Feb. 23, and runs through Friday, Feb. 24. It is the Children’s Center’s largest fundraising event of the year, and airs on the Baltimore radio station throughout the two days.

Newswise: Rapid Screening Test Predicts Effectiveness of Steroid Injections for Neck Pain
Released: 15-Feb-2023 9:00 AM EST
Rapid Screening Test Predicts Effectiveness of Steroid Injections for Neck Pain
Johns Hopkins Medicine

Researchers from Johns Hopkins Medicine and several other institutions say they have developed a quick clinical test that predicts which people with neck pain are more likely to benefit from epidural steroid injections, which deliver drugs directly around the spinal nerves to stop nerve inflammation and reduce pain.

Newswise: A Healthy Heart for Aidan
Released: 15-Feb-2023 8:00 AM EST
A Healthy Heart for Aidan
Johns Hopkins Medicine

If you look at Aidan Marcus, you would have no way of knowing everything he has gone through in his 17 months of life. His mom, Ambar, says, “He looks like a normal kid.” But when she was 22 weeks pregnant, she and her husband, Justin, who live in Silver Spring, Maryland, learned that their baby boy’s heart wasn’t developing properly. Aidan was diagnosed with hypoplastic left heart syndrome (HLHS), a congenital heart defect in which the left side of the heart is underdeveloped — a condition that affects about 1,000 newborns in the U.S. each year.

Newswise: CBD May Increase the Adverse Effects of THC in Edible Cannabis Products, Study Shows
Released: 13-Feb-2023 12:15 PM EST
CBD May Increase the Adverse Effects of THC in Edible Cannabis Products, Study Shows
Johns Hopkins Medicine

Contrary to some common claims, a study led by Johns Hopkins Medicine researchers found that relatively high doses of cannabidiol (CBD) may increase the adverse effects of delta-9-tetrahydrocannabinol (THC), the main active ingredient in cannabis that can cause a mood alteration or a “high” sensation. The findings show that in edible cannabis products, CBD inhibits the metabolism, or breakdown, of THC, which may result in stronger and longer drug effects.

Newswise: The Convergence of Epigenetics and Math to Predict and Intercept Cancer Cell Behavior
Released: 9-Feb-2023 3:45 PM EST
The Convergence of Epigenetics and Math to Predict and Intercept Cancer Cell Behavior
Johns Hopkins Medicine

It is now widely understood that cancer is a disease of acquired defects in genes and gene function. An article published Feb. 10 in Science, and authored by Andrew Feinberg, M.D., of the Johns Hopkins Kimmel Cancer Center and the Institute for Basic Biomedical Sciences (IBBS) and Andre Levchenko, Sc.D., M.S., of the Yale School of Engineering and Applied Science, addresses new quantitative approaches to better define and measure these defects in gene function, known as epigenetics, and their interplay with the genetic landscape of cancer.

Newswise: New Study Affirms Link Between Sickle Cell Disease and Risk of Increased Mortality in Pregnant People
Released: 2-Feb-2023 1:10 PM EST
New Study Affirms Link Between Sickle Cell Disease and Risk of Increased Mortality in Pregnant People
Johns Hopkins Medicine

Johns Hopkins Medicine researchers have further documented an association between a substantially higher risk of maternal morbidity and mortality among those with the inherited blood disorder sickle cell disease (SCD) compared to those without it. Their analysis, using a large national administrative database with records for pregnant people with SCD, found the maternal mortality rate was 26 times greater than the national average. This figure has not improved since the last time this population was assessed.

Newswise: Five Johns Hopkins Medicine Researchers Named Fellows of the American Association for the Advancement of Science
Released: 31-Jan-2023 10:05 AM EST
Five Johns Hopkins Medicine Researchers Named Fellows of the American Association for the Advancement of Science
Johns Hopkins Medicine

Five researchers from the Johns Hopkins University School of Medicine were elected as 2022 fellows of the American Association for the Advancement of Science (AAAS), the world’s largest general scientific society and a publisher of numerous journals, including Science.

Newswise: New Study Finds Depression, Poor Mental Health Linked to Higher Heart Disease Risks Among Young Adults
Released: 30-Jan-2023 10:00 AM EST
New Study Finds Depression, Poor Mental Health Linked to Higher Heart Disease Risks Among Young Adults
Johns Hopkins Medicine

Young adults who feel down or depressed are more likely to develop cardiovascular disease (CVD) and have poor heart health, according to a new study led by Johns Hopkins Medicine researchers who analyzed data from more than a half million people between the ages of 18 and 49. The findings add to a growing body of evidence connecting CVD with depression among young and middle-aged adults and suggest the relationship between the two could begin in early adulthood.

Newswise: Study Shows FDA-Approved TB Regimen May Not Work Against the Deadliest Form of TB Due to Multidrug-Resistant Strains
Released: 27-Jan-2023 9:20 AM EST
Study Shows FDA-Approved TB Regimen May Not Work Against the Deadliest Form of TB Due to Multidrug-Resistant Strains
Johns Hopkins Medicine

Johns Hopkins Medicine investigators say their research indicates a new combination of drugs is needed to find an effective treatment for TB meningitis due to multidrug-resistant (MDR) strains

Newswise: Johns Hopkins Physicians and Engineers Develop Search for AI Program That Accurately Predicts Risk of 'ICU Delirium'
Released: 26-Jan-2023 11:00 AM EST
Johns Hopkins Physicians and Engineers Develop Search for AI Program That Accurately Predicts Risk of 'ICU Delirium'
Johns Hopkins Medicine

More than one-third of all people admitted to the hospital, and as many as 80% of all patients in an intensive care unit (ICU), develop delirium, a type of brain dysfunction marked by sudden bouts of confusion, inattention, paranoia, or even agitation and hallucinations. An intensivist at Johns Hopkins Medicine, in collaboration with Johns Hopkins University engineering students, report they have developed artificial intelligence (AI) algorithms that can detect the early warning signs of delirium and can predict — at any time during an ICU stay — a high risk of delirium for a significant number of patients.

Newswise: ‘Hard to Lose’ Mutations in Tumors May Predict Response to Immunotherapy
25-Jan-2023 9:15 AM EST
‘Hard to Lose’ Mutations in Tumors May Predict Response to Immunotherapy
Johns Hopkins Medicine

Investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy have found that a subset of mutations within the overall TMB, termed “persistent mutations,” are less likely to be edited out as cancer evolves, rendering tumors continuously visible to the immune system and predisposing them to respond to immunotherapy.

Newswise: Keys to Making Immunotherapy Work Against Pancreatic Cancer Found in Tumor Microenvironment
Released: 26-Jan-2023 10:00 AM EST
Keys to Making Immunotherapy Work Against Pancreatic Cancer Found in Tumor Microenvironment
Johns Hopkins Medicine

A new study that analyzed the tumor microenvironment of pancreatic cancer revealed the cause of tumor cell resistance to immunotherapy and resulted in new treatment strategies.

Newswise: Researchers Unravel Why Episodes of Low Blood Sugar Worsen Eye Disease in People with Diabetes
Released: 26-Jan-2023 9:00 AM EST
Researchers Unravel Why Episodes of Low Blood Sugar Worsen Eye Disease in People with Diabetes
Johns Hopkins Medicine

People with diabetes who experience periods of low blood sugar — a common occurrence in those new to blood sugar management — are more likely to have worsening diabetic eye disease. Now, researchers at Johns Hopkins Medicine say they have linked such low blood sugar levels with a molecular pathway that is turned on in oxygen-starved cells in the eye.

Newswise: Nanofiber-Hydrogel Loaded with Stem Cells Shows Success Treating Severe Complication of Crohn’s Disease
Released: 25-Jan-2023 10:00 AM EST
Nanofiber-Hydrogel Loaded with Stem Cells Shows Success Treating Severe Complication of Crohn’s Disease
Johns Hopkins Medicine

In a new study using a rat model of Crohn’s disease, a biodegradable hydrogel composite loaded with stem cells, developed by Johns Hopkins Medicine researchers, in a collaborative effort with the Whiting School of Engineering, has shown significant success in treating perianal fistulas (PAF) — one of the many complications of Crohn’s disease.

Newswise: New Studies Suggest Social Isolation Is a Risk Factor for Dementia in Older Adults, Point to Ways to Reduce Risk
Released: 12-Jan-2023 10:00 AM EST
New Studies Suggest Social Isolation Is a Risk Factor for Dementia in Older Adults, Point to Ways to Reduce Risk
Johns Hopkins Medicine

In two studies using nationally representative data from the National Health and Aging Trends Study gathered on thousands of Americans, researchers from the Johns Hopkins University School of Medicine and Bloomberg School of Public Health have significantly added to evidence that social isolation is a substantial risk factor for dementia in community-dwelling (noninstitutionalized) older adults, and identified technology as an effective way to intervene.

Newswise: Key Change in Genetics of SARS-CoV-2 Evolved to Counter Weakness Caused by the Virus’ Initial Mutation that Enabled Its Spread
Released: 12-Jan-2023 9:00 AM EST
Key Change in Genetics of SARS-CoV-2 Evolved to Counter Weakness Caused by the Virus’ Initial Mutation that Enabled Its Spread
Johns Hopkins Medicine

Researchers at Johns Hopkins Medicine say their new studies suggest that the first pandemic-accelerating mutation in the SARS-CoV-2 virus, which causes COVID-19, evolved as a way to correct vulnerabilities caused by the mutation that started the SARS-CoV-2 pandemic.

Newswise: The Nose Knows: Study Suggests It May Be Wise to Screen for Smell Loss to Predict Frailty and Unhealthy Aging
Released: 10-Jan-2023 9:40 AM EST
The Nose Knows: Study Suggests It May Be Wise to Screen for Smell Loss to Predict Frailty and Unhealthy Aging
Johns Hopkins Medicine

In a study using data from nearly 1,200 older adults, Johns Hopkins Medicine researchers have added to a growing body of evidence that loss of the sense of smell is a predictive marker for an increased risk of frailty as people age.

Newswise: New Year, New Habits: Johns Hopkins Children’s Center Experts Weigh in on Tips to Kick-start Healthy Habits in 2023
Released: 9-Jan-2023 10:00 AM EST
New Year, New Habits: Johns Hopkins Children’s Center Experts Weigh in on Tips to Kick-start Healthy Habits in 2023
Johns Hopkins Medicine

The year 2023 is here. A new year symbolizes a fresh start and offers a renewed focus on health and well-being. Many people make resolutions regarding their health — and resolutions aren’t just for adults. They are for kids, too. Johns Hopkins Children’s Center experts are available to help parents kick-start healthy habits for their children and families in 2023.

Newswise: Taming Overactive mTOR in Renal Cell Cancer
Released: 3-Jan-2023 11:00 AM EST
Taming Overactive mTOR in Renal Cell Cancer
Johns Hopkins Medicine

In a new study from the Johns Hopkins Kimmel Cancer Center, researchers described a novel mechanism of tumor formation in kidney cancers.

Newswise: When Grandpa Can’t Hear Words at a Noisy Holiday Gathering, Too Many Brain Cells May Be Firing at Once, Say Researchers
Released: 22-Dec-2022 1:30 PM EST
When Grandpa Can’t Hear Words at a Noisy Holiday Gathering, Too Many Brain Cells May Be Firing at Once, Say Researchers
Johns Hopkins Medicine

Looking for answers about how the brain works amid age-related hearing loss, Johns Hopkins Medicine researchers say they found that old mice were less capable than young mice of “turning off” certain actively firing brain cells in the midst of ambient noise.

Newswise: Found! Lost Puzzle Piece Involved in Gene Regulation Revealed in Search That Began in Water-Loving, One-Celled Organism
Released: 22-Dec-2022 10:00 AM EST
Found! Lost Puzzle Piece Involved in Gene Regulation Revealed in Search That Began in Water-Loving, One-Celled Organism
Johns Hopkins Medicine

After an intrepid, decade-long search, Johns Hopkins Medicine scientists say they have found a new role for a pair of enzymes that regulate genome function and, when missing or mutated, are linked to diseases such as brain tumors, blood cancers and Kleefstra syndrome — a rare genetic, neurocognitive disorder.

Newswise: Program That Trains Community Health Workers to Deliver Hearing Care Shows Success Among Low-Income Older Adults
Released: 20-Dec-2022 11:20 AM EST
Program That Trains Community Health Workers to Deliver Hearing Care Shows Success Among Low-Income Older Adults
Johns Hopkins Medicine

A first-in-kind program that trains trusted older adult community health workers to fit and deliver low-cost hearing technology to peers with hearing loss significantly improved communication function among participants, according to the results of a randomized clinical trial led by Johns Hopkins Medicine researchers.

Newswise: New Computer Model Tracks Origin of Cell Changes That Drive Development
Released: 9-Dec-2022 5:05 PM EST
New Computer Model Tracks Origin of Cell Changes That Drive Development
Johns Hopkins Medicine

Scientists at Johns Hopkins Medicine say they have developed a computer model — dubbed quantitative fate mapping — that looks back in the developmental timeline to trace the origin of cells in a fully grown organism.

Newswise: Johns Hopkins Researchers Explore the Concept of Belief Changes Related to Psychedelic Experiences
Released: 9-Dec-2022 9:00 AM EST
Johns Hopkins Researchers Explore the Concept of Belief Changes Related to Psychedelic Experiences
Johns Hopkins Medicine

Johns Hopkins Medicine researchers continue their exploration into psychedelics and how these drugs may produce a wide range of profound changes in perception, cognition and mood.



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