By comparing the genomes of an alga, a weed and humans, a team of researchers has identified a new gene behind Bardet-Beidl syndrome (BBS), a complex condition marked by learning disabilities, vision loss and obesity.
A team that included a trauma surgeon renowned for his treatment of gunshot victims has found that exposing at-risk children and teenagers to grisly videos and photos of these patients' wounds can significantly change the youths' beliefs about the value and consequences of aggression.
1) High blood testosterone levels associated with increased prostate cancer risk; 2) Obese men may have increased risk for prostate cancer recurrence after surgery; 3) American Urological Association awards highest honor to Urology Chairman at Johns Hopkins
A new study finds that many hospitalized patients prefer visits from their own physician to those of the physicians on duty, even when those "visits" are virtual "telerounds."
Peanut allergy sufferers and their parents take note: a study finds that most soaps and household cleaners will remove enough peanut allergen from hands and dining surfaces at home and in schools to prevent an attack.
Once expected to die in early childhood, children born with HIV are now surviving into their teens and early adulthood. But it's also likely they will develop drug resistance. Researchers say that with careful planning and adherence to treatment plans, these patients can stay healthy.
The development of an aggressive but rare type of esophageal cancer in African-Americans may follow a different path than the same disease in whites, and is more likely to be fatal, according to results of a study.
The combination of real-time PET and CT is a highly sensitive tool for identifying non-small cell lung cancer and can assist in identifying patients whose cancer has not yet spread to lymph nodes, according to results of a study.
In experiments with rodents, Johns Hopkins scientists have used properly directed stem cells to successfully overcome what is thought to be a basic hurdle in restoring function to severely damaged central nervous systems -- getting new motor neurons to migrate through the spinal cord.
Kimmel Cancer Center researchers have identified a gene that when altered makes cells and animals age prematurely and die. The findings may provide a new target for therapies that force cancer cells to an early death.
An international team of researchers has discovered how disruption of a single gene contributes to a complex syndrome characterized in part by insatiable appetite.
Researchers have discovered that nitric oxide, a chemical messenger involved in bodily functions from erection to nerves' communication, also shuts down a protein involved in Parkinson's disease.
Two scientists have figured out a simple way to make millions upon millions of drug-like peptides quickly and efficiently, overcoming a major hurdle to creating and screening huge "libraries" of these super-short proteins for use in drug development.
Scientists have successfully used new techniques to search the yeast genome for genes that help keep copied chromosomes together, protecting the integrity of the organism's genetic material during cell division.
Scientists report that restricting the shape and personal space of human stem cells from bone marrow is more important than any known molecular signal in determining the cell type they become.
For students, residents and postdoctoral fellows at Johns Hopkins, conducting research is an opportunity to learn -- not just things they don't know, but things the world doesn't know.
So-called "exercise hypertension," an abnormally high spike in blood pressure experienced by generally healthy people during a workout, is a known risk factor for permanent and serious high blood pressure at rest. But who gets it, and why, has been largely unknown.
Older adults who volunteer in troubled urban schools not only improve the educational experience of children, but realize meaningful improvements in their own mental and physical health, say researchers.
Researchers at the Children's Center have designed an online, Web-based system for ordering total parenteral nutrition (TPN) that identifies and pre-emptively eliminates potentially serious calculation errors.
Researchers at the Children's Center report that 20 percent of children with asthma do not get enough exercise, even though physical activities such as running and swimming have been shown to decrease the severity of asthma symptoms.
This information tip sheet highlights newsworthy presentations from the Johns Hopkins Kimmel Cancer Center, scheduled at the 95th annual meeting of the American Association for Cancer Research.
Fetal heart monitoring does not identify babies who are diagnosed with white matter brain injury after birth, according to a new study. The study helps explain why the incidence of cerebral palsy in term infants has not changed since the 1960s.
Researchers have discovered a genetic defect that may be associated with a severe and often fatal infant lung disease.
Scientists at the Howard Hughes Medical Institute at Johns Hopkins have uncovered the first cue to the carefully choreographed growth of tiny blood vessels in the eye and ear. Their report will help improve understanding of major eye diseases, most of which stem from abnormal blood vessel growth in the light-detecting retina.
Scientists have discovered why arsenic has long been a successful way to treat certain leukemias, and in the process have shown that a combination of the poison and a second naturally occurring toxin may provide a potent new therapy for them.
Scientists have identified a switched-off family of genes that may prove to be a significant and early dent in a colon cell's anti-cancer armor. The inactivated genes, SFRPs (secreted frizzled-related protein), put the brake on a pathway of cell-growth genes that is a step en route to cancer.
Scientists have found mutations in a gene linked to the progression of colon and other cancers. The research findings may lead to new therapies and diagnostic tests that target this gene.
Researchers report from annual meeting: 1) Doctors identify new predictor of coronary artery disease; 2) A mom, not dad, with heart disease increases coronary heart disease risk in offspring; 3) Exercise prescriptions may significantly reduce coronary heart disease
Magnetic resonance imaging (MRI), coupled with the use of the contrast dye gadolinium, may help pediatricians better diagnose children with ulcerative colitis and Crohn's disease, according to a study by researchers.
Surgeons performed on Feb. 29, 2004, what is believed to be the world's first "triple swap" kidney transplant involving a new technique, called plasmapheresis, for removing the harmful antibodies that create incompatibilities between donors and recipients.
Researchers have for the first time used a chemical marker detected by proton magnetic resonance spectroscopic imaging to successfully diagnose breast cancer. The diagnostic technique produces pictures of choline within breast tumors.
The School of Nursing will host a special symposium highlighting the leadership role of nurses in addressing the health care and health policies needed to support the aging population.
A first-of-its-kind patient satisfaction study suggests that many patients tethered to a life-saving artificial kidney machine that cleanses the blood stream of wastes might have preferred a second option -- home-based peritoneal dialysis that uses the lining of the patient's belly as a natural filter -- if only they had been given a truly informed choice.
By identifying a 30-year-old mistaken assumption, scientists have found that substituting a simple bleach solution for more complex tools makes a DNA separation technique called electrophoresis five times faster and less costly.
In the rare but serious case of shoulder dystocia, in which an infant's shoulders get stuck in the birth canal after its head emerges, mother and baby might fare better if doctors use their hands to manipulate the baby's position to ease delivery than if they cut perineal tissue to widen the opening.
Medical malpractice cases frequently try to link injuries to the white matter of a newborn's brain "” a precursor to cerebral palsy and other disorders "” to the baby's delivery, though a new study demonstrates that such injuries are more closely associated with neonatal infections.
C-reactive protein (CRP) -- a marker of inflammation circulating in the blood already associated with increased risk of heart disease -- can also be used to identify a person's risk of developing colon cancer, according to a study.
Researchers at Johns Hopkins Children's Center and 35 other institutions nationwide report that two-thirds of current pediatric residents in the United States are satisfied with their required pediatric primary care training. Resident satisfaction was found to be most closely tied to the resident's preceptor, or mentor, and as a result, satisfied residents are more likely to identify good mentors, the researchers say.
Scientists hunting for culprits that lead to brain damage after strokes have discovered that one likely "bad guy" is actually a "good guy."
Limitations in the curricula of American medical schools may be preventing students from getting enough basic skills training to succeed in clinical settings, according to two studies.
A new report by the Genetics and Public Policy Center at Johns Hopkins University outlines policy options to address the scientific and ethical challenges raised by genetic testing of human embryos.
Efforts to increase organ donation among Native Americans may get a boost from research that is identifying the specific genetic makeup of the HLA system of human transplantation antigens among different Indian tribes. HLAs are used to determine the suitability of a match between an organ donor and recipient.
Researchers at Johns Hopkins have linked versions of two different genes with the inflammatory bowel diseases known as Crohn's disease and ulcerative colitis. The discoveries are a crucial step in developing new treatments and prevention strategies for these disabling conditions that together afflict one million Americans, the scientists say.
Scientists have discovered the first direct evidence in mammals that a chemical intermediate in the production of fatty acids is a key regulator of appetite, according to a report.
The international team of scientists working to determine the most common variations of the human genome report the details of their plans, known as the "HapMap" project.
Routine annual testing for abnormally high levels of protein in the urine "“ an early marker of kidney malfunction and premature death "“ should be limited to those with other risk factors and older Americans, a study indicates.
John Hopkins University Genetics and Public Policy Center is convening a diverse panel of thought leaders to discuss this potent new technology. The technique, called Preimplantation Genetic Diagnosis, can help parents avoid the birth of a child with a devastating genetic disease.
Researchers at Johns Hopkins say that combining various types of magnetic resonance imaging techniques more accurately sorts cancers from benign masses in breast tissues than any single imaging techniques.
Along with helping some people shed unwanted pounds, the popular low-carbohydrate, high-fat Atkins diet may also have a role in preventing seizures in children with epilepsy, say researchers.
A study gives eye doctors a precise way to identify premature babies at the highest risk of abnormal blood vessel growth in the retina and subsequent blindness. The computerized risk assessment tool they used should lead to treatment of retinopathy of prematurity at its earliest stages.
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