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5-Nov-2003 5:10 PM EST
Aspirin May Not Be Strong Enough to Prevent Clots in Some Heart Patients
Johns Hopkins Medicine

While an aspirin a day helps keep a heart attack at bay, it may need reinforcement to totally prevent blood clots among patients with chest pain, a study shows.

5-Nov-2003 12:40 PM EST
Region of Chromosome 1 Important in Blood Pressure Regulation
Johns Hopkins Medicine

Scientists are closing in on genetic contributors to high blood pressure and other causes of heart and cardiovascular disease. A research associate will present evidence that a region of chromosome 1 is involved in appropriately regulating blood pressure.

5-Nov-2003 12:30 PM EST
Genetic Aberration Helps Explain Variation in Cystic Fibrosis
Johns Hopkins Medicine

Researchers will reveal the existence of specific short repeats of particular genetic building blocks in the gene at the root of cystic fibrosis, an inherited and often fatal lung disease. The researchers will also show how the repetitious pattern may help predict the disease's severity.

5-Nov-2003 12:50 PM EST
Cellular Problem Discovered Behind Syndrome of Obesity, Learning Disabilities
Johns Hopkins Medicine

A research team has discovered a potential new contributor to obesity -- faulty cilia.

Released: 3-Nov-2003 4:50 PM EST
Children with HIV More Likely to Utilize Health Services Than Infected Adults
Johns Hopkins Medicine

Although more American adults than children are infected with the HIV virus, children with the disease use more HIV-related health care services, a researcher reports.

Released: 30-Oct-2003 4:20 PM EST
Excellent Survival Rates for Liver Cancer Patients Undergoing Transplant
Johns Hopkins Medicine

More than 60 percent of liver transplant patients with advanced liver cancer are still alive after five years, compared to nearly zero survival for those patients who did not undergo transplant, according to a study.

28-Oct-2003 3:40 PM EST
Team Approach Works Better to Reduce Blood Pressure in African-American Men
Johns Hopkins Medicine

A three-year study led by a nurse investigator has found that it may take a "village" to significantly lower the blood pressure of urban African-American men. "The traditional one-on-one doctor-patient visit in a doctor's office will simply not work."

24-Oct-2003 6:30 AM EDT
Biological Trick Reveals Key Step in Melatonin's Regulation
Johns Hopkins Medicine

Johns Hopkins researchers have uncovered a key step in the body's regulation of melatonin, a major sleep-related chemical in the brain. The research team reports finding the switch that causes destruction of the enzyme that makes melatonin -- no enzyme, no melatonin.

17-Oct-2003 7:40 AM EDT
Better Model of Cancer Development Sheds Light on Potential Angiogenesis Target
Johns Hopkins Medicine

Johns Hopkins Kimmel Cancer Center researchers have learned that a common, cancer-linked gene thought to control blood vessel growth may not turn out to be useful as an effective target for cancer drug development.

17-Oct-2003 1:10 PM EDT
Radiation Oncology Research News
Johns Hopkins Medicine

The following news tips are based on abstracts to be presented at the annual meeting of ASTRO. 1) Gene silencer may improve chemo and radiation; 2) Fighting the side effects of radiation

Released: 17-Oct-2003 12:30 PM EDT
Researchers Discover How Nitric Oxide Prevents Blood Vessel Inflammation
Johns Hopkins Medicine

Scientists investigating nitric oxide - the molecular messenger that contributes to body functions as wide-ranging as cell death, new blood vessel growth and erections - have figured out how it can block blood vessel inflammation and prevent clotting, a process that has long stumped biologists.

14-Oct-2003 4:50 PM EDT
Inability to Pump Oxygen During Exercise Could Pinpoint Early Heart Problems
Johns Hopkins Medicine

Mildly elevated blood pressure affecting millions of Americans could lead to heart pumping disorders if left untreated. The amount of oxygen that can be circulated throughout the body during each heart beat while exercising could reveal to doctors early signs of heart trouble in this population.

Released: 13-Oct-2003 4:40 PM EDT
Study Confirms Benefits of Hemispherectomy Surgery
Johns Hopkins Medicine

A new study confirms the lasting benefits of hemispherectomy, a dramatic operation in which half the brain is removed to relieve frequent severe seizures that medications cannot control.

6-Oct-2003 11:00 AM EDT
Hospitalization Injuries Prove Costly to Patients, Health Care System
Johns Hopkins Medicine

An analysis of more than 7 million recent discharge records from hospitals in 28 states reveals that a group of 18 medical injuries that occur during hospitalization may account for 2.4 million extra hospital days, $9.3 billion in excess charges, and almost 32,600 attributable US deaths annually.

Released: 3-Oct-2003 4:00 PM EDT
The Neighborhood Matters: Scientists Show Cell Environment Important in ALS
Johns Hopkins Medicine

In amyotrophic lateral sclerosis (ALS), neighborhood may be everything, if a new study in mouse models of the disease holds true for patients.

30-Sep-2003 4:00 PM EDT
Thorough, Searchable Database of Human Proteins Unveiled
Johns Hopkins Medicine

Like expert curators who verify and create catalogs of the world's great art collections, an international team of scientists has developed a human protein database they say will change the way biology is done. The team unveils the online Human Protein Reference Database.

Released: 30-Sep-2003 2:00 PM EDT
Manual, Low-Tech Method for 2nd Trimester Abortions Found Safe and Effective
Johns Hopkins Medicine

A hand-held vacuum aspiration device works as well as a more expensive electrical one for ending second-trimester pregnancies, according to results of a study.

Released: 24-Sep-2003 3:30 AM EDT
Avon Foundation Gives Landmark $10 Million Gift to Johns Hopkins Kimmel Cancer Center
Johns Hopkins Medicine

The Avon Foundation has awarded $10 million to the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins to build a new breast center, support research designed to decrease breast cancer incidence and death rates and fund education and outreach initiatives.

22-Sep-2003 6:00 AM EDT
Exercise Measures Identify Heart Disease in Seemingly Healthy Women
Johns Hopkins Medicine

A woman's fitness level and the time it takes for her heart to return to normal after exercise are more accurate predictors of female heart disease risk than electrical recordings of the heart, according to a national study led by Johns Hopkins researchers.

21-Sep-2003 12:00 AM EDT
Cellular Problem Discovered Behind Syndrome of Obesity, Learning Disabilities
Johns Hopkins Medicine

A research team led by Johns Hopkins scientists has discovered a potential new contributor to obesity -- faulty cilia.

Released: 16-Sep-2003 5:00 PM EDT
Surgeons Successfully Separate Nigerian Conjoined Twin Girls
Johns Hopkins Medicine

Surgeons on Thursday successfully separated 2-month-old conjoined twins Faithful and Favour Sobowale-Davies. The twins, from Lagos, Nigeria, had been joined at the abdomen and sternum (chest), and their livers had been fused.

11-Sep-2003 9:00 AM EDT
Simple Way To Reduce HIV Transmission From Mom to Baby
Johns Hopkins Medicine

Researchers report final results of a study showing that a safe, simple and inexpensive treatment reduces transmission of HIV from mothers to babies during childbirth and the first few weeks of life, offering a good chance to curb the spread of HIV.

11-Sep-2003 9:00 AM EDT
Bracing Is Less Effective In Overweight Teens With Scoliosis
Johns Hopkins Medicine

In teenagers, being overweight appears to threaten the success of wearing a back brace, the most commonly prescribed and only proven non-surgical treatment for curvature of the spine, say researchers.

Released: 10-Sep-2003 10:00 AM EDT
Similar Genetic Origins Possible for Schizophrenia and Bipolar Disorder
Johns Hopkins Medicine

A study appears to offer the first hard evidence that schizophrenia and bipolar disorder, severe psychoses that affect 2 percent of the population, may have similar genetic roots.

Released: 3-Sep-2003 5:00 PM EDT
Herbal Weight-Loss Product Information Can Be Misleading
Johns Hopkins Medicine

Many Internet sites marketing and advertising dietary supplements containing the herb ephedra are posting false or misleading information, a study demonstrates.

Released: 26-Aug-2003 4:00 PM EDT
Scientists: Cloak of Human Proteins Gets HIV Into Cells
Johns Hopkins Medicine

Researchers propose, for the first time, that HIV and other retroviruses can use a Trojan horse style of infection, taking advantage of a cloak of human proteins to sneak into cells.

14-Aug-2003 2:00 PM EDT
Ketogenic Diet Raises Cholesterol, Lipid Levels in Children
Johns Hopkins Medicine

Researchers report that the rigorously high-fat, low-carbohydrate diet known as the ketogenic diet, shown to reduce or eliminate difficult-to-control seizures in children with epilepsy, significantly raised children's cholesterol and levels of lipids and lipoproteins in the blood.

Released: 19-Aug-2003 12:00 PM EDT
Disease-Causing Genetic Mutations In Sperm Increase with Men's Age
Johns Hopkins Medicine

There's a lot said about a woman's ticking biological clock, but male biology doesn't age as gracefully as men might like to think. Scientists have discovered that older men's sperm is more likely to contain disease-causing genetic mutations that also seem to increase a sperm's chances of fertilizing an egg.

Released: 13-Aug-2003 4:00 PM EDT
Dedicated Trauma Program Improves Patient Outcomes
Johns Hopkins Medicine

A dedicated trauma service staffed by full-time specialists at hospitals can significantly reduce patient triage times in the emergency department (ED), help reduce ED overcrowding and lower death rates.

Released: 12-Aug-2003 3:00 PM EDT
Natural Hormone Could Reverse Heart Damage
Johns Hopkins Medicine

By altering the signaling pathway of the natural hormone leptin doctors may one day be able to minimize or even reverse a dangerous enlarged heart condition linked to obesity.

Released: 11-Aug-2003 2:00 PM EDT
Summer News Tips
Johns Hopkins Medicine

Story ideas from The Johns Hopkins Medical Institutions: 1)How to achieve that healthy tan without the harm; 2)Being sun safe; 3)Prevent dehydration; 4)Prevent commonplace injuries this summer

5-Aug-2003 5:00 PM EDT
Gene Therapy Delays Death in Mouse With Symptoms of Lou Gehrig's Disease
Johns Hopkins Medicine

It's not a cure, but a novel form of gene therapy has delayed symptoms and almost doubled life expectancy in mice with the equivalent of Lou Gehrig's disease.

Released: 7-Aug-2003 2:00 PM EDT
Home Visits From Community Health Workers Spur Blood Pressure Reduction
Johns Hopkins Medicine

As little as one home visit by a community health worker, as part of a community/academic health center program, may be enough to encourage someone with high blood pressure to take measures to lower it.

Released: 6-Aug-2003 4:00 PM EDT
Home Ownership = Fewer Emergency Department Visits By Local Population
Johns Hopkins Medicine

A study has found that even in relatively impoverished neighborhoods, home ownership is linked to lower rates of use of emergency departments for emergent and general medical care.

Released: 5-Aug-2003 5:00 PM EDT
Dr. Robot Tested
Johns Hopkins Medicine

It lacks the warm bedside manner of Marcus Welby or Dr. Kildare, but a high-tech robot could be used to link patients with their physicians in a whole new way.

Released: 4-Aug-2003 1:00 PM EDT
Reproductive Genetics Advisory Committee Named
Johns Hopkins Medicine

The Genetics and Public Policy Center at The Johns Hopkins University has established the Reproductive Genetics Advisory Committee to provide expert advice on the scientific, medical, legal, social, ethical, and policy issues that accompany genetic testing, gene transfer and cloning technologies and their potential applications to human reproduction.

Released: 1-Aug-2003 5:00 PM EDT
Surgeons Perform World's First 'Triple Swap' Kidney Transplant
Johns Hopkins Medicine

Surgeons on July 28 performed what is believed to be the world's first "triple swap" kidney transplant operation, giving a woman from Miami, a woman from Pittsburgh and a child from Washington, D.C., new leases on life.

Released: 29-Jul-2003 1:00 PM EDT
Immune System Drug May Increase Availability of Liver Transplants
Johns Hopkins Medicine

Animal research has found that a drug already approved by the FDA for testing in people might one day dramatically expand the number of livers useable for human transplantation.

Released: 23-Jul-2003 4:00 PM EDT
Treatment for Depression is Safe and Effective for Alzheimer's
Johns Hopkins Medicine

Researchers have shown that a drug commonly used for depression, also improves quality of life and alleviates disruption in daily activities for the one-quarter of Alzheimer's patients who also suffer from major depression.

22-Jul-2003 4:00 PM EDT
Growth-Stimulating Cue Identified for Nerve Cells
Johns Hopkins Medicine

For decades, scientists have hunted for signals that guide nerve cells' tentacle-like axons, hoping to understand how these cell tips reach out to distant targets. It's knowledge that might one day help researchers learn how to rebuild nerves lost to spinal cord injuries or diseases like Huntington's.

11-Jul-2003 12:00 AM EDT
Depression in African-American Men and High Blood Pressure Control
Johns Hopkins Medicine

A study from The Johns Hopkins University School of Nursing concludes depression may sabotage efforts to control high blood pressure in urban, African-American men.

Released: 15-Jul-2003 12:00 AM EDT
Inflammation Blocks Impact of Heart Healthy Diets for Some
Johns Hopkins Medicine

Results of a Johns Hopkins study suggest that natural chemicals released in the body as a result of chronic inflammation may underpin the failure of low-fat, so-called heart healthy diets to actually reduce cholesterol and heart disease risk in some people.

Released: 14-Jul-2003 12:00 AM EDT
Changing Focus of Hospital "Rounds" Improves Patient Care
Johns Hopkins Medicine

Researchers at Johns Hopkins are challenging a practice that's almost as old as American medicine: the venerable doctors' "rounds," visiting hospitalized patients daily to check their health status with eager, white-coated medical students and residents scurrying along from bed to bed as each case is reviewed and discussed.

13-Jul-2003 12:00 AM EDT
Adult and Embryonic Stem Cells and the Future of Research
Johns Hopkins Medicine

At an American Association for Cancer Research forum Johns Hopkins' Curt Civin, M.D., will lead a discussion about stem cell research and policy and their relation to cancer research.

10-Jul-2003 12:00 AM EDT
Children May Outgrow Peanut Allergies
Johns Hopkins Medicine

Parents whose kids are allergic to peanuts may be relieved to know that it's possible their children could outgrow their allergy over time.

Released: 8-Jul-2003 12:00 AM EDT
Pre-Diabetic Adults at Increased Risk of Colon Cancer
Johns Hopkins Medicine

People with impaired glucose tolerance (IGT), a precursor to diabetes, are at increased risk of dying from colon and other cancers, according to a study directed by Johns Hopkins researchers.

1-Jul-2003 12:00 AM EDT
Unemployment, Access to Guns Turn Domestic Violence Deadly
Johns Hopkins Medicine

Access to guns, threats to kill and most of all, unemployment, are the biggest predictors of the murder of women in abusive relationships, concludes a nationwide case control study led by a professor at The Johns Hopkins University School of Nursing.

28-Jun-2003 12:00 AM EDT
Human Stem Cells Improve Movement in Paralyzed Rats
Johns Hopkins Medicine

Johns Hopkins researchers report that injection of human stem cells into the fluid around the spinal cord of each of 15 paralyzed rats clearly improved the animals' ability to control their hind limbs -- but not at all in the way the scientists had expected.

Released: 24-Jun-2003 12:00 AM EDT
"Reverse CPR" Performed on Back Could Better Restore Blood Flow
Johns Hopkins Medicine

A pilot study of the first proposed major change in decades to cardiopulmonary resuscitation suggests that performing the maneuver while patients are on their stomachs offers far better restoration of blood flow and blood pressure than the standard practice of keeping patients on their backs.



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