A Johns Hopkins-led research team has successfully used a technique to rapidly find fruit fly genes involved in a cell signaling pathway called Hedgehog, which is critical to proper embryo development and a key trigger in some cancers, including the deadly childhood brain cancer medulloblastoma.
Listed below are story ideas from The Johns Hopkins University School of Medicine's Division of Sports Medicine.
Researchers from the Johns Hopkins Children's Center report that a group of rare urological defects, including bladder development outside the body, may be more common in children conceived through in vitro fertilization (IVF). The researchers caution, however, that the findings are preliminary, and should not necessarily dissuade couples from considering the procedure.
Johns Hopkins scientists have discovered that primitive human embryonic stem (ES) cells, temperamental in the lab, can be grown with the help of special cells from bone marrow, offering an easily obtained and well-studied source of human cells to nurture the human ES cells as they divide.
Johns Hopkins scientists have found a way to predict with a simple blood test which people may be at higher than normal risk for the most common form of colon cancer.
Johns Hopkins researchers last year reported that an experimental treatment for severe ragweed allergy consisting of just six shots in six weeks dramatically reduced allergic symptoms such as runny nose, nasal congestion and sneezing, and nearly eliminated the need for relief medications like antihistamines and decongestants.
Researchers at the Johns Hopkins Children's Center and the Johns Hopkins Bloomberg School of Public Health report that male rats whose mothers were fed diets containing genistein, a chemical found in soybeans, developed abnormal reproductive organs and experienced sexual dysfunction as adults.
Studying mice, scientists from Johns Hopkins have successfully prevented a molecular event in brain cells that they've found is required for storing spatial memories.
By studying mice, Johns Hopkins scientists have discovered that excessive activity of an important signaling protein, TGF-beta, likely underlies a variety of problems in Marfan syndrome, including the tendency to develop emphysema.
Treating women for precancerous cervical lesions the same day they are discovered could reduce cervical cancer rates in developing nations, according to a study of Thai women by researchers at Johns Hopkins and their Thai colleagues.
New work by researchers in the Kimmel Cancer Center at Johns Hopkins may allow them to halt the smoking-induced cellular events that lead to 99 percent of all small cell lung cancers.
As effective vaccines against HIV remain elusive, Johns Hopkins researchers have completed the first tests to see if a drug already used to treat HIV infection might one day be used to prevent sexual and blood-borne transmission of the virus that causes AIDS.
Research by Johns Hopkins epidemiologists has confirmed what some have long suspected about consent forms required of clinical trial volunteers: They use language far too difficult for most people to understand.
Below are brief descriptions of two presentations, one on using microarrays to study gene expression in the brain, and the other on the new vision of the nucleus.
A new study of teenage girls with menstrual problems and other hormone-related symptoms finds they are far more worried about their future fertility that their healthy age-mates and need more health care and counseling than they are getting.
A team of scientists from Johns Hopkins and the biotechnology company Genitope has unlocked the 3-D structure of a receptor that goes awry in 20 percent to 30 percent of breast cancers. The scientists also figured out how the receptor, known as HER2, interacts with an antibody, sold as Herceptin, that is used to treat thousands of breast cancer patients each year.
Combining an exercise stress test with an image of blood flow through the heart may be an effective method to predict and prevent heart attacks and other events among adult siblings of heart disease patients, a Johns Hopkins study has found.
Using specialized pacemakers to recharge the weakened hearts of heart failure patients can halve the death rate from the disease and reduce hospitalizations by nearly a third, a Johns Hopkins study has found.
Researchers at the Johns Hopkins Kimmel Cancer Center have discovered that loss of a gene already implicated in human cancers also leads to age- and gender-linked cancers in mice.
Doctors may not have to deliver a baby early if it has low amniotic fluid surrounding it, Johns Hopkins obstetricians report.
1) Food aphrodisiacs -- fact or fiction? 2) Weight loss and nutrition myths: how much do we know?; 3) Eating healthy with ethnic food. 4) New trends in exercise alternatives
Johns Hopkins' popular ABX (antibiotic treatment) Guide, currently used on mobile communications devices and personal computers by more than 115,000 registered individuals, is now available on BlackBerry Wireless Handhelds from Research In Motion.
Teenagers seeking confidential health care for such conditions as pregnancy or sexually transmitted diseases frequently get inaccurate information about their doctor's confidentiality policies.
Using the same technology that creates tiny, precisely organized computer chips, a Johns Hopkins research team has developed beds of thousands of independently moveable silicone "microneedles" to reveal the force exerted by smooth muscle cells.
After years spent analyzing blood banking and transfusion practices in China, a Johns Hopkins-led research team says that major improvements are needed to ensure the safety and reliability of the blood supply that serves 20 percent of the world's population.
Johns Hopkins infection control experts who last year traced the source of a bacterial infection in 32 patients to three defective bronchoscopes say more rigorous regulation and faster recall of the devices may have prevented the outbreak.
A research team led by Johns Hopkins scientists has discovered that a special, tiny group of cells at the back of the eye help tell the brain how much light there is, causing the pupil to get bigger or smaller.
Computed tomography (CT) scans widely marketed to consumers may not be valuable for mass screening of lung cancer, a Johns Hopkins study has found.
Researchers at Johns Hopkins report success in using high doses of the anti-cancer drug cyclophosphamide to treat patients with moderate and severe forms of lupus, a chronic and sometimes fatal autoimmune disease.
Whether or not a doctor recommends a child for kidney transplantation often depends on the child's track record for sticking to a medication regimen, researchers at the Johns Hopkins Children's Center report.
Scientists from Johns Hopkins and the University of Wisconsin have discovered that a protein called Sir2, which is found in nearly all living cells, has a new function that might help explain how calorie restriction can increase lifespans for some animals, the scientists say.
Race, gender and other social factors may explain why some parents allow their children to play with toy guns, while others shudder at the thought, a Johns Hopkins researcher reports.
Faulty cell communication is at the root of a complex and rare disorder that affects many of the body's structures and systems, including the eyes, face, teeth, fingers and toes, a Hopkins-led research team has discovered.
Researchers at the Johns Hopkins Children's Center report that two doses of the varicella vaccine for chicken pox given one to two months apart can be safe and effective in children with chronic kidney disease.
Scientists from the Kimmel Cancer Center at Johns Hopkins and Northwestern University have found a new target to squeeze off a tumor's blood supply. Research shows how a common cancer-causing gene controls the switch for tumor blood vessel growth known as angiogenesis.
Men infected with a combination of hepatitis B virus and HIV are 17 times more likely to die from liver disease than men infected with hepatitis B alone, according to a study by researchers at Johns Hopkins.
A review of scores of studies testing the benefits of exercise in people with cramping leg pain, the most common symptom of peripheral arterial disease, suggests that regular walking -- while painful -- is worth it.
Tipsheet: 1) Extended-release drugs convenient and safer for seizure patients; 2) Cause of seizures may play a role in predicting success of pediatric hemidecortication surgery.
The notion of a trim, fighting force probably dates back more than 2,000 years. Today, each branch of the U. S. armed services has developed a "Maximum Allowable Weight" chart to screen and determine eligibility for entry into the military.
Researchers from the Johns Hopkins Children's Center report that hemispherectomy -- a procedure in which half the brain is removed -- may reduce or eliminate severe seizures even in older children with a rare congenital disorder associated with epilepsy.
Hopkins radiologists have found that a combination of positron emission tomography and computed tomography detects cancer spread better than PET alone.
1) Eating disorders and young adults; 2) Ways to watch your waistline at the holidays; 3) Holiday food tips for people with diabetes.
The Johns Hopkins scientists who first discovered that knocking out a particular muscle gene results in "mighty mice" now report that it also softens the effects of a genetic mutation that causes muscular dystrophy.
Bilirubin has been a mystery of a molecule, associated with better health if there's just a little more than normal, but best known for being at the root of the yellow color in jaundice and, at high levels, for causing brain damage in newborns. Johns Hopkins scientists have now solved the enigma of how this toxic molecule can also be beneficial.
A battery-operated compression belt buckled around the chest restores blood flow better than manual chest compressions and conventional CPR, according to a Johns Hopkins-led animal study.
Scientists at Johns Hopkins have successfully detected ovarian cancer using a blood test for DNA shed by tumors. The test is based on digital analysis of single nucleotide polymorphisms, in which investigators separate the two strands of code found in every gene to search for imbalances that are a hallmark of cancer cell DNA.
A Johns Hopkins-led study shows that two proteins, C-reactive protein and albumin, are accurate predictors of heart attack or stroke in kidney dialysis patients.
Scientists from Johns Hopkins and Washington University School of Medicine in St. Louis have discovered that in vitro fertilization appears to be associated with a rare combination of birth defects characterized by excessive growth of various tissues.
Researchers at Johns Hopkins Bayview Medical Center have found evidence of a physiologic basis for the frailty often observed in geriatric patients.
There is reassuring news for families and medical staff who care for children who spike fevers following hemispherectomy, a surgery in which half the brain is removed to relieve frequent severe seizures that medications cannot control.
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