Morbidity and Mortality of Meningioma Resection Increases in Octogenarians

A presentation at the 2016 American Association of Neurological Surgeons Annual Scientific Meeting

Article ID: 652467

Released: 2-May-2016 11:05 AM EDT

Source Newsroom: American Association of Neurological Surgeons (AANS)

Newswise — Winner of the Integra Foundation Award, Jeremy Steinberger, MD, presented his research, Morbidity and Mortality of Meningioma Resection Increases in Octogenarians, during the 2016 American Association of Neurological Surgeons (AANS) Annual Scientific Meeting.

This study utilizes a large national database to assess outcomes in octogenarians undergoing surgery for meningioma, as large-scale studies examining the effect outcomes in this group after meningioma surgery had not been conducted.

Patients were identified by CPT code in the NSQIP database. Univariate analysis was performed to compare demographics, comorbidities and postoperative complications in patients of different ages. Multivariate step-wise logistic regression was performed on each complication that demonstrated significant association with age in the univariate comparison.

In the database, 1,568 patients were identified. On univariate analysis, patients under 50 had overall complication rates of 17.9 percent, while patients aged 71-80 had rates of 29.6 percent and patients above 80 had rates of 31.2 percent. Specifically, patients in the 71–80 group and <80 group had higher rates of pulmonary complications, deep venous thromboses/pulmonary embolisms and urinary tract infections. Patients under 50 had a length of stay greater than five days 32.3 percent of the time, while patients aged 71–80 and over 80 rates were 49.2 percent and 64.5 percent, respectively.

Age had a significant impact on mortality. Patients under 50 had a 30-day mortality rate of 0.7 percent, while patients 71-80 had mortality rates of 2.5 percent and patients over 80 had mortality rates of 8.6 percent. On multivariate analysis, patients over the age of 80 were at higher risk of overall complications and prolonged length of stay. Death within 30 days was 15 times higher in patients over 80, compared to the younger groups.

In evaluating the effect of age in 1,568 patients undergoing meningioma surgery, 80 years old seems to be the statistical cut off for significantly increased morbidity and mortality.

Author Block: Jeremy Steinberger, MD; Nathan Lee, BA; Parth Kothari, BA; Ahmed Awad, MD; Christopher Sarkiss, MD; Eric Oermann, MD; John Caridi, MD; Raj Shrivastava, MD (New York)

Disclosure: The author reported no conflicts of interest.

Media Representatives: The 2016 AANS Annual Scientific Meeting press section will include releases on highlighted scientific research, AANS officers and award winners, Neurosurgery Awareness Month and other relevant information about the 2016 program. Releases will be posted under the “Media” area on the 2016 AANS Annual Scientific Meeting website. If you have interest in a topic related to neurosurgery or would like to interview a neurosurgeon — either onsite or via telephone — during the event, please contact Alice Kelsey, AANS associate executive director, via email at aik@aans.org.

About the 2016 AANS Annual Scientific Meeting: Attended by neurosurgeons, neurosurgical residents, medical students, neuroscience nurses, clinical specialists, physician assistants, allied health professionals and other medical professionals, the AANS Annual Scientific Meeting is the largest gathering of neurosurgeons in the nation, with an emphasis on the field’s latest research and technological advances. More than 1,200 scientific abstracts were submitted for the 2015 AANS Annual Scientific Meeting; the scientific presentations accepted for the 2016 event will represent cutting-edge examples of the incredible developments taking place within the field of neurosurgery. Additional information about the 2016 AANS Annual Scientific Meeting and the meeting program can be found here.

Founded in 1931 as the Harvey Cushing Society, the American Association of Neurological Surgeons (AANS) is a scientific and educational association with more than 10,000 members worldwide. The AANS is dedicated to advancing the specialty of neurological surgery in order to provide the highest quality of neurosurgical care to the public. Fellows of the AANS are board-certified by the American Board of Neurological Surgery, the Royal College of Physicians and Surgeons of Canada or the Mexican Council of Neurological Surgery, A.C. Neurosurgery is the medical specialty concerned with the prevention, diagnosis, treatment and rehabilitation of disorders that affect the spinal column, spinal cord, brain, nervous system and peripheral nerves.

For more information, visit www.AANS.org.

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