THE JOHNS HOPKINS UNIVERSITYOFFICE OF NEWS AND INFORMATION3003 N. Charles Street, Suite 100Baltimore, Maryland 21218-3843Phone: (410) 516-7160 / Fax (410) 516-5251

DATE: February 25, 2003

TO: Reporters, producers and editors

RE: New contraceptive microbicide in clinical trials

Researchers at the Johns Hopkins University and ReProtect LLC have developed a gel for women that may both help block the spread of sexually transmitted diseases and reduce unwanted pregnancies.

The compound, known as BufferGel, is currently in advanced clinical trials for its ability to prevent pregnancy. Trials of its ability to block HIV transmission are scheduled to be under way soon.

When applied vaginally prior to intercourse, BufferGel maintains vaginal acidity at its normal levels, which can kill both sperm and many germs. A video news release on BufferGel is available online at:

http://www.jhu.edu/news_info/news/audio-video/buffergel.html

Copies of the videotape are available on request. An earlier news release on BufferGel is online at http://www.jhu.edu/news_info/news/home02/jan02/germs.html

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