Shedding Light on Disease: A Briefing for Journalists

Thursday, October 23, 2003, 10 a.m. - 12 p.m., Eastern TimeLive Webcast at http://www.bnl.gov/video

Slides posted at: http://newsroom.mbooth.com/bnl/PressBriefing_10-03/

WHAT: A two-hour Webcast on leading edge disease research, sponsored by the U.S. Department of Energy's Brookhaven National Laboratory, exclusively for working journalists. Hear directly from scientists at Brookhaven's National Synchrotron Light Source (NSLS), who are using advanced imaging technologies in order to identify and understand a range of diseases.

SCHEDULE: 10 a.m. — Welcome -- John Carter, Director of Community Affairs, U.S. Department of Energy, Brookhaven Area Office10:05 a.m. — Overview -- Steven Dierker, Ph.D., Associate Laboratory Director for Light Sources and Chair of the NSLS

10:10 a.m. — Developing Novel Drugs to Treat Infectious Diseases Walter F. Mangel, Ph.D., Biology DepartmentMany viruses, bacteria, and parasites continue to baffle modern medicine. But scientists at Brookhaven's NSLS are discovering the biochemical reactions that activate these pathogens and are using this knowledge to develop novel drugs to treat them.

10:35 a.m. — Understanding Microdamage in Osteoporosis Treatment Lisa Miller, Ph.D., National Synchrotron Light SourceDrugs to treat osteoporosis are now used routinely because they can effectively increase bone density"¦ but do they also cause damage to bones? Hear about just-published studies on the microscopic effects of these medications.

11:00 a.m. — Inhibiting the Effects of Botulism Subramanyam Swaminathan, Ph.D., Biology DepartmentBotulinum toxin is among the most neurotoxic of nerve agents. Discover how research at the NSLS has helped identify the three-dimensional structure of this paralyzing protein, and how these structural studies may lead to ways to inhibit the toxin's debilitating effects.

11:25 a.m. — High-Contrast, Low-Dose X-Rays for Soft-Tissue Imaging Zhong Zhong, Ph.D., National Synchrotron Light SourceWhile there have been tremendous advances in x-ray imaging, there is still not an optimal way to image soft tissues. Now, Brookhaven scientists have developed a new X-ray technique that has produced the most detailed images yet of the breast and other soft tissues.

11:50 a.m. — Open Q & A for all speakers