CHOP Researchers Find NTRK Fusions More Common than Expected in Pediatric Tumors

In a large study of pediatric cancer patients, researchers from Children’s Hospital of Philadelphia (CHOP) have analyzed the frequency, fusion partners, and clinical outcome of neurotrophic tyrosine receptor kinase (NTRK) fusions, which are...
15-Jan-2021 9:45 AM EST Add to Favorites

CHOP and Penn Researchers Identify Nanoparticles that Could Be Used in Therapeutic mRNA Delivery before Birth

Researchers at Children’s Hospital of Philadelphia and the School of Engineering and Applied Science at the University of Pennsylvania have identified ionizable lipid nanoparticles that could be used to deliver mRNA as part of fetal therapy. The...
13-Jan-2021 7:50 AM EST Add to Favorites

Youth with Family History of Suicide Attempts Have Worse Neurocognitive Functioning

Children and adolescents with a family history of suicide attempts have lower executive functioning, shorter attention spans, and poorer language reasoning than those without a family history, according to a new study by researchers from the...
11-Jan-2021 9:45 AM EST Add to Favorites

Long-Term Study Finds Dozens of New Genetic Markers Associated with Lifetime Bone Growth

A multidisciplinary team of researchers has discovered several genetic markers associated with bone mineral accrual, which could ultimately help identify causes of eventual osteoporosis earlier in life through genetic testing
6-Jan-2021 9:40 AM EST Add to Favorites

Nearly Half of Young Drivers Are Resuming Driving Just Weeks After Sustaining a Concussion

Researchers found that nearly half of adolescents who sought specialty care for a concussion were back to driving when asked approximately two weeks after the injury, even though few had returned to exercise and sports.
11-Dec-2020 10:55 AM EST Add to Favorites

CHOP Researchers Find Elevated Biomarker Related to Blood Vessel Damage in All Children with SARS-CoV-2 Regardless of Disease Severity

Researchers at Children’s Hospital of Philadelphia (CHOP) have found elevated levels of a biomarker related to blood vessel damage in children with SARS-CoV-2 infection, even if the children had minimal or no symptoms of COVID-19. They also found...
8-Dec-2020 10:15 AM EST Add to Favorites

Study Finds No Change in Preterm Birth or Stillbirth in Philadelphia During Pandemic Period

Despite early reports suggesting a decline in preterm births during the COVID-19 pandemic period, an analysis by researchers at Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania has...
7-Dec-2020 3:35 PM EST Add to Favorites

Kidney Injury in Diabetic Ketoacidosis Linked to Brain Injury

Researchers have identified factors that make children with diabetic ketoacidosis more likely to experience acute kidney injury. Analyzing data from a large, multicenter clinical trial, the researchers also found that children who experience acute...
2-Dec-2020 2:00 PM EST Add to Favorites

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