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Biomarker, Clues to Possible Therapy Found in Novel Childhood Neurogenetic Disease

Researchers studying a rare genetic disorder that causes severe, progressive neurological problems in childhood have discovered insights into biological mechanisms that drive the disease, along with early clues that an amino acid supplement might...
22-Feb-2018 11:00 AM EST Add to Favorites

Hearing Loss Is Common After Infant Heart Surgery

Children who have heart surgery as infants are at risk for hearing loss, coupled with associated risks for language, attention and cognitive problems, by age four. In a single-center group of 348 preschoolers who survived cardiac surgery,...
15-Feb-2018 3:00 PM EST Add to Favorites

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T Cell Therapy Shows Persistent Benefits in Young Leukemia Patients

Updated results from a global clinical trial of the CAR T-cell therapy, tisagenlecleucel, a landmark personalized treatment for a high-risk form of acute lymphoblastic leukemia (ALL), reveal that children and young adults continued to show high...
26-Jan-2018 12:20 PM EST Add to Favorites

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For Children with Respiratory Infections, Antibiotics with Narrower Targets Are Better

A study of 30,000 children with earaches, strep throat and other common infections found that narrow-spectrum antibiotics had fewer adverse effects than broad-spectrum antibiotics. A more selective approach is better, said researchers.
30-Jan-2018 3:05 PM EST Add to Favorites

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Can Vitamins and Dietary Supplements Benefit Patients with Mitochondrial Disease?

Defects in mitochondria, the tiny structures that power our cells by functioning as biological batteries, cause an array of complex, often life-threatening disorders that can affect any and all organs and systems. In the absence of validated,...
10-Jan-2018 12:05 PM EST Add to Favorites

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One-Dose Gene Therapy Produces Clotting Factor, Safely Stops Bleeding in Hemophilia B Patients

A team of gene therapy researchers has reported positive results in a phase 1/2 clinical trial for the inherited bleeding disorder hemophilia B. A single intravenous infusion of a novel bioengineered gene therapy treatment enabled adult participants...
1-Dec-2017 4:55 PM EST Add to Favorites

Brain Remaps Itself in a Child with Double Hand Transplant

The first child to undergo a successful hand transplant also is the first child in whom scientists have detected massive changes in how sensations from the hands are represented in the brain. The brain reorganization is thought to have begun six...
5-Dec-2017 9:30 AM EST Add to Favorites

Researchers from Children's Hospital of Philadelphia Highlight Advances in Pediatric Heart Disease at 2017 A.H.A. Scientific Sessions

Physician-researchers from the Cardiac Center at Children’s Hospital of Philadelphia recently presented new findings on pediatric cardiovascular disease at the American Heart Association’s Scientific Sessions 2017 in Anaheim, Calif. Among many...
28-Nov-2017 1:45 PM EST Add to Favorites


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Our Experts on Newswise

Over 50 experts from Children’s Hospital of Philadelphia will address colleagues at this year’s annual meeting of the American Academy of Pediatrics (AAP) on current issues in vaccine education, autism, sports injuries, gastroenterology,...
15-Sep-2017 6:05 AM EDT

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4-Apr-2016 3:05 PM EDT

An international group of more than 800 medical experts at the nation’s largest pediatric cardiology conference are discussing challenges in treating congenital heart disease in fetuses, neonates, children and young adults.
11-Feb-2015 4:00 PM EST

Guidelines released today by Canadian pediatric emergency medicine researchers are in line with the work that has been taking place over the past several years at CHOP to help improve pediatric concussion diagnosis and treatment and standardize...
25-Jun-2014 4:20 PM EDT

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28-May-2014 1:00 PM EDT

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16-Jan-2013 7:00 AM EST

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