CHOP Researchers Establish Novel Approach for Developing New Antibiotics

Researchers at Children’s Hospital of Philadelphia (CHOP) have developed a novel method for producing new antibiotics to combat resistant bacteria. Through an approach that would target bacteria with an antibiotic that is masked by a prodrug,...
19-Jul-2021 10:55 AM EDT Add to Favorites

CHOP Researchers Use Base Editing in Preclinical Model to Correct Lethal Lysosomal Storage Disease Before Birth

Adding to the growing body of literature demonstrating the feasibility of correcting lethal genetic diseases before birth, researchers at Children’s Hospital of Philadelphia (CHOP) have used DNA base editing in a prenatal mouse model to correct a...
9-Jul-2021 11:15 AM EDT Add to Favorites

CHOP Researchers Discover Unique Immune Response by Cells Critical to Lung Health

Researchers at Children’s Hospital of Philadelphia (CHOP) have discovered that a specific type of lung cell exhibits unconventional immune properties and may contribute to the outcome of respiratory viral infections. The researchers focused on...
28-Jun-2021 11:05 AM EDT Add to Favorites

ADHD Medications Associated with Reduced Risk of Suicidality in Children with Significant Behavioral Symptoms

ADHD medications may lower suicide risk in children with hyperactivity, oppositional defiance and other behavioral disorders, according to new research from the Lifespan Brain Institute (LiBI) of Children’s Hospital of Philadelphia (CHOP) and the...
2-Jun-2021 2:05 PM EDT Add to Favorites

CHOP Researchers Develop Proof-of-Concept Treatment that Elevates Both Adult and Fetal Hemoglobin

Researchers at Children’s Hospital of Philadelphia (CHOP) have developed a proof-of-concept treatment for blood disorders like sickle cell disease and beta-thalassemia that could raise hemoglobin levels by activating production of both fetal and...
1-Jun-2021 10:30 AM EDT Add to Favorites

Children’s Hospital of Philadelphia Appoints Susan L. Furth, MD, PhD as New Chief Scientific Officer

Following an extensive national search, Children’s Hospital of Philadelphia (CHOP) has appointed Susan L. Furth, MD, PhD as Chief Scientific Officer. In her new position, effective June 1, 2021, Dr. Furth will oversee the CHOP Research Institute,...
1-Jun-2021 9:35 AM EDT Add to Favorites

Researchers Show How Mitochondrial Function Influences Schizophrenia Status in Patients with Genetic Disorder

A multidisciplinary team of researchers showed how the “batteries” of cells are highly implicated in whether patients with the chromosome 22q11.2 deletion syndrome develop schizophrenia. The results of the study may eventually lead to targeted...
18-May-2021 10:10 AM EDT Add to Favorites

Researchers Discover New Genetic Variants Responsible for Neurodevelopmental Disorders

Researchers have revealed how variants of a gene responsible for packing and condensing genetic material present a novel cause for certain neurodevelopmental disorders.
10-May-2021 10:35 AM EDT Add to Favorites