Opioid Dependence Found to Permanently Change Brains of Rats

Approximately one-quarter of patients who are prescribed opioids for chronic pain misuse them, with five to 10 percent developing an opioid use disorder or addiction. In a new study, UC San Diego researchers found that opioid dependence produced...
24-Jan-2020 1:05 PM EST Add to Favorites

Liver Fibrosis 'Off Switch' Discovered in Mice

UC San Diego School of Medicine researchers identified several genetic switches, or transcription factors, that determine whether or not liver cells produce collagen — providing a new therapeutic target for liver fibrosis.
23-Jan-2020 1:45 PM EST Add to Favorites

Zika Virus’ Key into Brain Cells ID’d, Leveraged to Block Infection and Kill Cancer Cells

Two different UC San Diego research teams identified the same molecule — αvβ5 integrin — as Zika virus’ key to brain cell entry. They found ways to take advantage of the integrin to both block Zika virus from infecting cells and turn it into...
14-Jan-2020 3:35 PM EST Add to Favorites

Researchers Identify Gene with Functional Role in Aging of Eye

Researchers say a gene known to be a biomarker of age plays a key role in age-associated functional and anatomical aging in mouse retinas, a finding that has direct relevance to age-related eye diseases.
15-Jan-2020 1:15 PM EST Add to Favorites

In Mice, Alcohol Dependence Results in Brain-Wide Remodeling of Functional Architecture

Using novel imaging technologies, researchers produce first whole-brain atlas at single-cell resolution, revealing how alcohol addiction and abstinence remodel neural physiology and function in mice.
14-Jan-2020 4:50 PM EST Add to Favorites

Unfruitful: Eating More Produce Will Not Cure, Stop Prostate Cancer

University of California San Diego School of Medicine researchers report that patients with prostate cancer assigned to eat seven or more servings of vegetables and fruits daily saw no extra protection from the increased consumption of...
14-Jan-2020 12:30 PM EST Add to Favorites

How Marijuana Accelerates Growth of HPV-related Head and Neck Cancer Identified

University of California San Diego School of Medicine researchers identified how THC from marijuana accelerates cancer growth in patients with human papillomavirus (HPV)-positive head and neck cancer.
13-Jan-2020 11:55 AM EST Add to Favorites

Taking One for the Team: How Bacteria Self-Destruct to Fight Viral Infections

UC San Diego School of Medicine researchers have discovered how a new immune system works to protect bacteria from phages, viruses that infect bacteria — new information that could be leveraged to improve treatment of multidrug-resistant bacterial...
8-Jan-2020 4:05 PM EST Add to Favorites

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