Title:  International Consensus Definition of Low Anterior Resection Syndrome
Description: This is the first definition of low anterior resection syndrome developed with direct input from a large international patient panel. The involvement of patients in all phases has ensured that the definition presented encompasses the vital aspects of the patient experience of low anterior resection syndrome. The novel separation of symptoms and consequences may enable greater sensitivity to detect changes in low anterior resection syndrome over time and with intervention.


Title: Increased 30-day mortality risk in patients with diabetes following colon cancer surgery: a mediation analysis
Video Creator:  Mario Schootman; Donna Jeffe; Kendra Ratnapradipa; Jan Eberth; Nicholas Davidson
Description:  Better management and prevention of anemia and sepsis among patients with diabetes mellitus may reduce their increased risk of death after colon
cancer resection.

Title: Prediction of poor response to neoadjuvant chemoradiation in rectal cancer patients using a DNA repair deregulation score - Picking the losers instead of winners
Video Creator:  Leandro Jimenez, MS; Rodrigo Oliva Perez, MD, PhD; Guilherme Pagin São Julião, MD; Bruna Vailati, MD; Laura Fernandez, MD; Joaquim Gama-Rodrigues, MD, PhD; Angelita Habr-Gama, MD, PhD; Jennifer DeVecchio, MB; Matthew Kalady, MD, PhD; Anamaria Camargo, PhD
Description: A DNA repair gene score may predict patients likely to have poor response to chemoradiation. This score may be a relevant tool to be investigated in future studies focused on chemoradiation used in the context of organ preservation.

Title: Centralizing Rectal Cancer Surgery: What’s the Impact on Travel for Patients?
Video Creator:  Zhaomin Xu, MD, MPH; Christopher T. Aquina, MD, MPH; Carla F. Justiniano, MD, MPH; Adan Z. Becerra, PhD; Francis P. Boscoe, PhD; Maria J. Schymura, PhD; Larissa K. Temple, MD, MSc; Fergal J. Fleming, MD  
Description: The number of hospitals performing rectal cancer resections in New York State is decreasing and volume by center is increasing. There was a statistically significant difference in the mean distance traveled by patients over time. If rectal cancer resections were centralized to high-volume centers, the mean travel distance would increase by 9.5 miles. There would be a 321% increase in the number of patients having to travel 50+ miles for surgery. Any plan for centralization in New York State will require careful planning to avoid placing undue travel burden on patients.

Title: Short-term and long-term outcome of endoluminal vacuum therapy for colorectal or coloanal anastomotic leakage: Results of a nationwide multicenter cohort study from the French GRECCAR group
Video Creator:  Solafah Abdalla, MD; Eddy Cotte, MD, PhD; Antoine Epin, MD; Karoui Mehdi, MD, PhD; Jérémie H Lefèvre, MD, PhD; Anne Berger, MD, PhD; Frederic Marchal, MD; Quentin Denost, MD; Christophe Penna, MD; Stephane Benoist, MD, PhD; Antoine Brouquet, MD, PhD
Description:  Endoluminal vacuum therapy appears to be effective to treat colorectal anastomotic leakage especially when it is used as primary treatment of the fistula. Long-term functional outcome of patients undergoing conservative management of anastomotic leakage may be improved with endoluminal vacuum therapy.

Title: Neutropenic enterocolitis – clinical features and outcomes
Video Creator:   Hamzah Abu-Sbeih, MD; Faisal S. Ali, MD; Ellie Chen, MD; Niharika Mallepally, MD; Wenyi Luo, MD; Yang Lu, MD; Wai Chin Foo, MD; Wei Qiao, PhD; Pablo C. Okhuysen, MD; Javier A. Adachi, MD; Ray Y. Hachem, MD; Mehmet Altan, MD; Robert R. Jenq, MD; Yinghong Wang, MD PhD
Description:  The prompt diagnosis and management of neutropenic enterocolitis are critical to prevent complications. The use of granulocyte colony-stimulating factor can be beneficial to shorten the duration of neutropenia.


 Authors: Beyer-Berjot, Laura M.D., Ph.D.1; Maggiori, Léon M.D., Ph.D.2; Loiseau, Didier M.D.3; De Korwin, Jean-Dominique M.D., Ph.D.4; Bongiovanni, Jean-Pierre M.D.5; Lesprit, Philippe M.D.6; Salles, Nathalie M.D.7; Rousset, Pascal M.D., Ph.D.8; Lescot, Thomas M.D., Ph.D.9; Henriot, Aymeric M.D.10; Lefrançois, Magalie M.D.11; Cotte, Eddy M.D., Ph.D.12; Parc, Yann M.D., Ph.D.13
Description: High-quality studies showed that laparoscopic peritoneal lavage was associated with an increased morbidity and that Hartmann procedure was associated with poorer long-term outcomes than primary resection with anastomosis with ileostomy, but Hartmann procedure is still acceptable, especially in high-risk patients.


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Diseases of the Colon & Rectum Journal, March 2020