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Medicine

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Cancer, Radiotherapy, Immune Response

Ludwig Researchers Unravel Novel Mechanism by Which Tumors Grow Resistant to Radiotherapy

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A Ludwig Cancer Research study has uncovered a key mechanism by which tumors develop resistance to radiation therapy and shown how such resistance might be overcome with drugs that are currently under development.

Science

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Ocean, microplastics, Plastic, Sea, environmenntal science, Environment, Environment and Life Sciences, Environment And Sustainability, micrometre

‘Lost’ 99% of Ocean Microplastics to Be Identified with Dye?

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The smallest microplastics in our oceans – which go largely undetected and are potentially harmful – could be more effectively identified using an innovative and inexpensive new method, developed by researchers at the University of Warwick.

Science

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Diabetes, Angiogenesis, Blood Vessel Formation, Ischemic Injury, VEGF, Ras protein

Scientists Find Key to Regenerating Blood Vessels

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Florida researchers have identified a signaling pathway that is essential for angiogenesis, the growth of new blood vessels from pre-existing vessels. The findings, published in Nature Communications, may improve current strategies to improve blood flow in ischemic tissue, such as that found in atherosclerosis and peripheral vascular disease associated with diabetes.

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Business

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WINE, Australia, salt-tolerance, grapevine, Salinity, plantbreeding, Genetics, Genetic Markers, rootstocks

New Discovery to Accelerate Development of Salt-Tolerant Grapevines

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A recent discovery by Australian scientists is likely to improve the sustainability of the Australian wine sector and significantly accelerate the breeding of more robust salt-tolerant grapevines.

Medicine

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Congenital Heart Disease

Children with Heart Disease Are Being Let Down by Lack of Clinical Trials, Study Finds

Less than one per cent of UK children born with congenital heart disease are enrolled in clinical trials looking to improve treatments, research by the University of Birmingham has found.

Medicine

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ACA, Affordable Care Act , Affordable Care Act (ACA), Cardiovascular care, aspirin therapy, Diabetes, High Blood Pressure and Heart Disease, High Blood Pressure, Hypertension, Smoking, U.S. Preventive Services Task Force, Uspstf

Under Affordable Care Act, Americans Have Had More Preventive Care for Heart Health, UCLA Study Finds

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By reducing out-of-pocket costs for preventive treatment, the Affordable Care Act appears to have encouraged more people to have health screenings related to their cardiovascular health, a UCLA study found.

Science

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Energy, Building Design, Renewable Energy, Solar Energy, Chemical Sciences & Engineering, Materials Science

Solar Cell Discovery Opens a New Window to Powering Tomorrow’s Cities

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Windows that generate electricity may have a clearer path to prominent roles in buildings of the future due to an Argonne-led discovery.

Medicine

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Case Western Reserve School of Medicine, NIH, Creutzfeldt Jacob Disease, CJD, Prions, prion transmission, National Prion Disease Pathology Surveillance Center , Wenquan Zou, CJD diagnosis, prion infections, Brain Health, Byron Caughey, Surgeries, Brain Surgery, non-neurosurgeries, Neurosurgeries, University Hospitals Cleveland Medical Center

Researchers Find Infectious Prions in Creutzfeldt-Jakob Disease Patient Skin

In a Science Translational Medicine study published today, Case Western Reserve University School of Medicine researchers found that CJD patients also harbor infectious prions in their skin, albeit at lower levels. In the study, the researchers collected skin samples from 38 patients with assistance from the National Prion Disease Pathology Surveillance Center at Case Western Reserve School of Medicine and measured their prion levels. Using a highly sensitive in vitro assay developed and conducted by Byron Caughey’s group at the NIH, they detected prion protein aggregates in the skin samples from all of CJD patients. Prion levels were 1,000-100,000 times lower in the skin than in the brain, and only detectable by this extremely sensitive assay. The researchers further demonstrated that such skin prions are infectious, since they are capable of causing disease in humanized mouse models.

Medicine

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High Deductible Health Plans, Deductibles, Health Insurance, Chronic Illness

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 27-Nov-2017 11:00 AM EST

Medicine

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Superbugs, Carbapenem-resistant Enterobacteriaceae , Epidemiology, whole-genome analysis, Bioinfomatics, Systems Biology, Klebsiella

New Approach to Tracking How Deadly 'Superbugs’ Travel Could Slow Their Spread

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Using a real-world outbreak as a test case, a team combined patient transfer data and whole-genome sequencing to identify hotspots for transmission of antibiotic-resistant bacteria.







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