While people who eat a lot of red meat are known to be at higher risk for certain cancers, other carnivores are not, prompting researchers at the University of California, San Diego School of Medicine to investigate the possible tumor-forming role of a sugar called Neu5Gc, which is naturally found in most mammals but not in humans.
A new study led by researchers at University of California, San Diego School of Medicine finds that the brains of obese children literally light up differently when tasting sugar.
Thomas Savides, MD has been named as the first Chief Experience Officer at UC San Diego Health System. In the newly created role, Savides will be responsible for the strategy, leadership and implementation of the plan to improve the total health care experience of patients, families, providers and staff.
The bacterium Salmonella Typhi causes typhoid fever in humans, but leaves other mammals unaffected. Researchers at University of California, San Diego and Yale University Schools of Medicine now offer one explanation — CMAH, an enzyme that humans lack. Without this enzyme, a toxin deployed by the bacteria is much better able to bind and enter human cells, making us sick.
For the second time, The Leapfrog Group has named UC San Diego Health System to its annual list of Top Hospitals. Awarded to hospitals nationwide for demonstrating excellence in hospital safety and quality, the Leapfrog Top Hospital award is an elite distinction given to less than seven percent of all eligible hospitals.
UC San Diego Health System and Imperial Valley Family Care Medical Group are pleased to announce a comprehensive affiliation that will enhance the depth and quality of multi-specialty health care services and clinical trials available to patients in the Imperial Valley and surrounding communities.
The bacterium Helicobacter pylori is strongly associated with gastric ulcers and cancer. To combat the infection, researchers at University of California, San Diego School of Medicine and Jacobs School of Engineering developed LipoLLA, a therapeutic nanoparticle that contains linolenic acid, a component in vegetable oils. In mice, LipoLLA was safe and more effective against H. pylori infection than standard antibiotic treatments.
High blood pressure and nonalcoholic fatty liver disease (NAFLD) are two emerging health problems related to the epidemic of childhood obesity. In a recent study, researchers at University of California, San Diego School of Medicine sought to determine the prevalence of high blood pressure in children with NAFLD, which places them at risk for premature cardiovascular disease.
UC San Diego Health System in partnership with the U.S. Hereditary Angioedema Association (HAEA) has opened the nation’s first dedicated center for diagnosing and treating diverse forms of swelling, known collectively as angioedema.
People with moderate to severe obstructive sleep apnea may have an intrinsic inability to burn high amounts of oxygen during strenuous aerobic exercise, according to a new study led by researchers at University of California, San Diego School of Medicine.
UC San Diego Health System is a world leader in chronic thromboembolic pulmonary hypertension and now with a $7.6 million grant, has helped launch the first national CTEPH registry to improve best practices and patient care.
While investigating a rare genetic disorder, researchers at the University of California, San Diego School of Medicine have discovered that a ubiquitous signaling molecule is crucial to cellular reprogramming, a finding with significant implications for stem cell-based regenerative medicine, wound repair therapies and potential cancer treatments.
For more than a century, the laboratory mouse has stood in for humans in experiments ranging from deciphering disease and brain function to explaining social behaviors and the nature of obesity. The small rodent has proven to be an indispensable biological tool, the basis for decades of profound scientific discovery and medical progress.
An antibody therapy already in clinical trials to treat chronic lymphocytic leukemia may also prove effective against ovarian cancer – and likely other cancers as well, report researchers at the University of California, San Diego School of Medicine.
Triclosan is an antimicrobial commonly found in soaps, shampoos, toothpastes and many other household items. Despite its widespread use, researchers at University of California, San Diego School of Medicine report potentially serious consequences of long-term exposure to the chemical.
Researchers at University of California, San Diego School of Medicine have developed a way to chemically disguise RNAi drugs so that they are able to enter cells. Once inside, cellular machinery converts these disguised drug precursors — called siRNNs — into active RNAi drugs.
Bess Marcus, PhD, has been appointed senior associate dean for Public Health with the UC San Diego School of Medicine.
Thomas Moore, MD has been named dean of Clinical Affairs and CEO for Faculty Practice at UC San Diego Health Sciences.
With the help of mouse models, induced pluripotent stem cells (iPSCs) and the “tooth fairy,” researchers at the University of California, San Diego School of Medicine have implicated a new gene in idiopathic or non-syndromic autism.
Imagine being able to recognize your car as your own but never being able to remember where you parked it. Researchers at University of California, San Diego School of Medicine have induced this all-too-common human experience – or a close version of it – permanently in rats and from what is observed perhaps derive clues about why strokes and Alzheimer’s disease can destroy a person’s sense of direction.
Updating its unique Hospital Safety Score, which assigns A, B, C, D and F grades to hospitals nationwide based on their ability to prevent errors, injuries and infections, UC San Diego Health System has again been awarded separate A ratings for its hospitals in Hillcrest and La Jolla by The Leapfrog Group.
Researchers at University of California, San Diego School of Medicine are launching a new program to help businesses in the San Diego region end the epidemic of distracted driving and the suffering and loss of life that can result.
Researchers at the University of California, San Diego School of Medicine describe the surprising and crucial involvement of a pro-inflammatory signaling protein in the creation of hematopoietic stem cells (HScs) during embryonic development, a finding that could help scientists to finally reproduce HSCs for therapeutic use.
Every day in America, roughly 10,000 people turn age 65. To help keep roadways safe as America grays and to help preserve the freedom of mobility of older drivers, researchers at University of California, San Diego School of Medicine are training law enforcement officers to recognize warning signs of impaired driving skills and to take appropriate, compassionate action.
In a study published in the Nov. 1 issue of Neural Computation, researchers at the University of California, San Diego School of Medicine report that a high quality brand of coenzyme Q10 (CoQ10) – a compound commonly sold as a dietary supplement – provides health benefits to persons suffering from Gulf War illness symptoms.
Researchers at University of California, San Diego School of Medicine have validated an EEG test to study and treat schizophrenia. The findings, published in two separate studies, offer a clinical test that could be used to help diagnose persons at risk for developing mental illness later in life, as well as an approach for measuring the efficacies of different treatment options.
In a push to further speed clinical development of emerging stem cell therapies, Sanford Stem Cell Clinical Center at UC San Diego Health System was named today one of three new “alpha clinics” by the California Institute for Regenerative Medicine, the state’s stem cell agency.
Richard Kronick, PhD, a health policy expert and faculty member at University of California, San Diego School of Medicine, has been elected to the prestigious Institute of Medicine.
UC San Diego Sanford Stem Cell Clinical Center is pushing therapeutic stem cell-based science out of the laboratory and closer to real-world medical applications. The unprecedented trials involve potential therapies for spinal cord injuries, Type 1 diabetes and chronic lymphocytic leukemia.
Researchers at the University of California, San Diego School of Medicine have identified a new fusion protein found in approximately 15 percent of secondary glioblastomas or brain tumors. The finding offers new insights into the cause of this cancer and provides a therapeutic target for personalized oncologic care.
Researchers at University of California, San Diego School of Medicine have been awarded a $9.2 million grant to help modernize and transform how researchers share, use, find and cite biomedical datasets.
Using X-rays and neutron beams, a team of researchers from the University of California, San Diego School of Medicine, University of Utah and Oak Ridge National Laboratory have teased out new information about Protein Kinase A, a ubiquitous master switch that helps regulate fundamental cellular functions like energy consumption and interactions with hormones, neurotransmitters and drugs.
Two professors of psychiatry at University of California, San Diego School of Medicine have been honored by the New York City-based Brain & Behavior Research Foundation for their work studying the genetics, dysfunction and treatment of schizophrenia, a chronic and severe brain disorder affecting roughly 1 percent of the general population or approximately 3 million people.
Researchers at the University of California, San Diego School of Medicine have, for the first time, clearly defined the epidemiology of gastrointestinal stromal tumors (GIST), which occur primarily in the lining of the stomach and small intestine. One key finding: Patients of Asian descent, who have not previously been identified as an at-risk population, are 1.5 times more likely than other patient groups to be diagnosed with this type of tumor.
Researchers at the University of California, San Diego School of Medicine have identified a microRNA molecule as a surprisingly crucial player in managing cell survival and growth. The findings underscore the emerging recognition that non-coding RNAs help regulate basic cellular processes and may be key to developing new drugs and therapies.
Researchers at University of California, San Diego School of Medicine have discovered that T-cells – a type of white blood cell that learns to recognize and attack microbial pathogens – are activated by a pain receptor.
Researchers at University of California, San Diego School of Medicine are co-recipients of a $4.1-million grant from the National Institutes of Health to advance treatments for type 1 diabetes. Using human stem cells, the team plans to culture bits of human pancreas in a dish and, using microfluidics, mimic blood flow through the islet.
More than 600 health care and construction workers donned pink hard hats while forming a giant human ribbon at the UC San Diego Jacobs Medical Center construction site today in support of National Breast Cancer Awareness month.
Researchers at the University of California, San Diego School of Medicine have launched a Phase III clinical trial to evaluate the drug isradipine, a calcium channel blocker often used to treat high blood pressure, as a potential new treatment for Parkinson disease.
Researchers have found that a key neuronal protein called alpha-synuclein normally gathers in synapses, where aggregates of it help regulate neurotransmissions. In overabundance, though, a-synuclein can choke off communication altogether, leading to neuronal death and related diseases.
In a paper published this week online in Global Society, researchers with University of California, San Diego School of Medicine and the Urban Studies and Planning Program, also at UC San Diego, present a bioregional guide that merges place-based (territorial) city planning and ecosystem management along the United States-Mexico border as way to improve human and environmental health.
More than 100 physicians from UC San Diego Health System were named “Top Docs” in the annual San Diego Magazine “Physicians of Exceptional Excellence” annual survey. These physicians represent 40 diverse specialties, from internal medicine and oncology to obstetrics, cardiovascular and surgical care.
The concept of a whole eye transplant seems futuristic, if not impossible. But with a $1million grant from the U.S. Department of Defense, researchers at University of California, San Diego School of Medicine hope to someday make implantation of an entire, functional eye a reality.
In a paper published September 17 in the online journal Magnetic Resonance in Medicine, researchers at the University of California, San Diego School of Medicine, University of Pittsburgh and elsewhere describe the first human tests of using a perfluorocarbon (PFC) tracer in combination with non-invasive magnetic resonance imaging to track therapeutic immune cells injected into patients with colorectal cancer.
UC San Diego Sulpizio Cardiovascular Center (SCVC) has been named among "100 Hospitals with Great Heart Programs" by Becker's Hospital Review, a business and legal news publication for hospital and health system leadership.
Researchers at University of California, San Diego School of Medicine have identified a control mechanism for an area of the brain that processes sensory and emotive information that humans experience as “disappointment.”
Researchers at the University of California, San Diego School of Medicine have launched a phase 1 human clinical trial to assess the safety and efficacy of a new monoclonal antibody for patients with chronic lymphocytic leukemia, the most common form of blood cancer in adults.
During cancer development, tumor cells decorate their surfaces with sugar compounds called glycans that are different from those found on normal, healthy cells. Researchers at the University of California, San Diego School of Medicine report that sialic acids at the tips of these cancer cell glycans are capable of engaging with immune system cells and changing the latter’s response to the tumor – for good and bad.
Using human induced pluripotent stem cells (hiPSCs), researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California, San Diego have discovered that neurons from patients with schizophrenia secrete higher amounts of three neurotransmitters broadly implicated in a range of psychiatric disorders.
Napoleone Ferrara, MD, Distinguished Professor of Pathology and Distinguished Adjunct Professor of Ophthalmology at the University of California, San Diego School of Medicine and senior deputy director for basic sciences at UC San Diego Moores Cancer Center, was named today as one of seven recipients of the António Champalimaud Vision Award in Lisbon, Portugal.
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