Researchers at the Moores Cancer Center at the University of California, San Diego (UCSD) are conducting clinical trials of a novel therapy aimed at revving up the immune system to combat a particularly difficult-to-treat form of leukemia.
An international research team, including University of California, San Diego School of Medicine professor Ajit Varki, M.D., has uncovered the first example of a bacterium that causes food poisoning in humans when it targets a non-human molecule absorbed into the body through red meats such as lamb, pork and beef.
The University of California, San Diego School of Medicine has received a contract from the National Institutes of Health (NIH) to enhance and maintain the Neuroscience Information Framework (NIF) "“ a dynamic inventory of web-based neurosciences data, resources, and tools that scientists and students can access via any computer connected to the Internet.
The Skaggs School of Pharmacy and Pharmaceutical Sciences at UCSD will collaborate with the American Pharmacists Association, the American Society of Health-System Pharmacists, and the American Association of Colleges of Pharmacy to promote PharmGenEd, in an educational campaign to more than 100,000 pharmacy practitioners and students across the country.
Researchers at the University of California, San Diego School of Medicine have identified a critical metabolic "switch" in fruit flies that helps oxygen-deprived cells survive.
"Essentials of Glycobiology," the largest and most authoritative text in its field, will be freely available online beginning October 15, through collaboration between the Consortium of Glycobiology Editors, the Cold Spring Harbor Laboratory Press, and the National Center for Biotechnology Information (NCBI), a division of the National Library of Medicine (NLM) at the National Institutes of Health (NIH).
A clinical trial led by Paul S. Aisen, M.D., professor of neurosciences at the University of California, San Diego School of Medicine, showed that high-dose vitamin B supplements did not slow the rate of cognitive decline in patients with mild to moderate Alzheimer disease.
Oncologists at the Moores UCSD Cancer Center are hoping to stave off the relentless march of advanced lung cancer by treating patients with a novel kind of cancer vaccine. While many vaccines attempt to pump up the immune system to fight off a cancer, the new vaccine, Lucanix, is genetically engineered to also trick the cancer into turning off its immune system-suppressing activities.
A study led by researchers at the University of California, San Diego School of Medicine suggests that use of oral Vitamin D supplements bolsters production of a protective chemical normally found in the skin, and may help prevent skin infections that are a common result of atopic dermatitis, the most common form of eczema.
A study of the first approximately 100 patients who have received partial breast irradiation with a small, whisk-like, expandable device inserted inside the breast has shown that after one year, the device is effective at sparing nearby healthy tissue from the effects of radiation.
In an editorial response to a report in the September 25 issue of The New England Journal of Medicine on the efficacy of intravenous thrombolysis treatment in the hours after acute ischemic stroke, Patrick Lyden, M.D., professor of neurosciences and director of the UC San Diego Stroke Center, cautions that the study should not be interpreted to mean that such therapy can be withheld for hours or even minutes.
Peter Novick, Ph.D., whose groundbreaking work in the field of cell biology has contributed to a novel understanding of internal cellular transportation systems, has been named the George E. Palade Endowed Chair of Cellular and Molecular Medicine at the UC San Diego School of Medicine.
On Tuesday, September 16, 2008, the UCSD center for the Future of Surgery performed the nation's first gastrectomy, a partial removal of the stomach, through the vagina. This new "natural orifice" technique may be an attractive alternative for the 200,000 U.S. patients who undergo surgery for the treatment of obesity each year.
University of California, San Diego is partnering with The University of Alabama at Birmingham (UAB) to develop new methods to treat and prevent kidney failure. UAB's Division of Nephrology has been awarded a five-year, $4.23 million George M. O'Brien Kidney Research Center grant from the National Institutes of Health.
The University of California, San Diego School of Medicine will lead a $60 million, five-year, 10-site Clinical Consortium funded by the Department of Defense Psychological Health/Traumatic Brain Injury Research Program to conduct studies leading to the prevention and treatment of posttraumatic stress disorder and traumatic brain injury.
A multidisciplinary group of researchers at UCSD, along with colleagues at the Salk Institute for Biological Studies in La Jolla, have established a center to formally explore the origins of humanity and the many facets of what makes us human. To celebrate its opening, The Center for Academic Research and Training in Anthropogeny, will present a symposium featuring expert speakers from around the world.
Reviewing findings from multiple disciplines, Jamey Marth, Ph.D., UCSD Professor of Cellular and Molecular Medicine and Investigator with the Howard Hughes Medical Institute, realized that only 68 molecular building blocks are used to construct these four fundamental components of cells: the nucleic acids (DNA and RNA), proteins, glycans and lipids.
In a collaborative study at the University of California, San Diego, investigators from neurosciences, chemistry and medicine, as well as the San Diego Supercomputer Center (SDSC) have investigated how proteins involved in neurodegenerative diseases such as Alzheimer's and Parkinson's disease interact to form unique complexes.
Researchers at the Moores Cancer Center at the University of California, San Diego (UC SD) in La Jolla have found evidence explaining why a common chemotherapy drug, cisplatin, may not always work for every cancer patient. They have shown that when a variant version of a key protein that normally causes cell death is active, patients may be resistant to the cancer-killing drug.
In a study that underscores the important role that individual genetic profiles will play in the development of new therapies for disease, a multi-institutional research team "“ led by Kang Zhang, MD, PhD professor of ophthalmology and human genetics at Shiley Eye Center at the UCSD School of Medicine "“ has made two important discoveries related to age-related macular degeneration (AMD).
School children across the world may speak different languages but there is one experience an estimated 90 percent of all students share: wearing a backpack. Researchers from the University of San Diego, California School of Medicine say those students also share a common problem: low back pain due to overloaded backpacks.
"Flesh-eating" or "Strep" bacteria are able to survive and spread in the body by degrading a key immune defense molecule, according to researchers at the UCSD School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences. The finding will be reported in the August 14 issue of the journal Cell Host & Microbe.
Researchers at UC San Diego Medical Center have launched a comprehensive program to study how breast milk can be fed to premature infants and to identify the ingredients that give human milk its life-boosting qualities. Called Supporting Premature Infant Nutrition (SPIN), the new program is focused on the provision, analysis, and research of human milk.
In a double-blind, placebo-controlled clinical trial to assess the impact of smoked medical cannabis, or marijuana, on the neuropathic pain associated with HIV, researchers at the University of California, San Diego School of Medicine found that reported pain relief was greater with cannabis than with a placebo.
Texas Hold'em poker has exploded in popularity over the past few years. Its popularity has extended to academic researchers. Now, poker-playing artificial intelligence systems, developed by a researcher at the University of California, San Diego School of Medicine, have been released for free use by the public.
With heart disease maintaining top billing as the leading cause of death in the United States, a team of University of California, San Diego School of Medicine physician-researchers is proposing that aggressive intervention to lower cholesterol levels as early as childhood is the best approach available today to reducing the incidence of coronary heart disease.
In a study that sheds new light on how memory and spatial cognition are related to each other in the brain, researchers at the University of California, San Diego School of Medicine and the Veteran Affairs (VA) San Diego Healthcare System studied memory-impaired patients as they navigated their environment.
Researchers at the University of California, San Diego Medical Center say that their first-of-its-kind study of a telemedicine program which transports stroke specialists via computer desktop or even laptop to the patient's bedside, using highly sophisticated video, audio and Internet technology, could have an immediate and profound impact on the treatment of stroke patients throughout the world.
Male injection drug users deported from the United States to Tijuana have four-fold higher odds of HIV infection compared to those living in Tijuana who were not deported there, according to a study to be presented at the International AIDS Conference on August 5, 2008 in Mexico City.
A team of researchers at the University of California, San Diego School of Medicine has uncovered a new signaling mechanism used to activate protein kinases that are critical for the body's inflammatory response. Their work will be published in the July 18 online edition of Science (Science Express).
A University of California, San Diego School of Medicine researcher has developed the first tissue culture of normal, human liver cells that can model infection with the Hepatitis C virus (HCV) and provide a realistic environment to evaluate possible treatments.
A new treatment strategy using molecular "smart bombs" to target metastasis with anti-cancer drugs leads to good results using significantly lower doses of toxic chemotherapy, with less collateral damage to surrounding tissue, according to a collaborative team of researchers at the University of California, San Diego.
Patients suffering from severe arthritis now have an option for total ankle replacement that offers increased mobility and pain relief without permanent metal implants. Pioneered by Daniel K. Lee, D.P.M., F.A.C.F.A.S., at UC San Diego Medical Center, this technique is the first in the U.S to offer arthritis sufferers a non-metal, biological ankle replacement.
The University of California, San Diego Medical Center's Hyperbaric Medicine Center is part of a nationwide effort to compile and evaluate data in order to validate whether cancer patients being treated for radiation-related wounds heal more quickly and more thoroughly with hyperbaric oxygen therapy.
In a first-of-its-kind study, research results show that toenail nicotine levels can help predict risk of coronary heart disease (CHD) in women. Researchers at UCSD School of Medicine, in collaboration with colleagues from Harvard University, showed that the higher the level of nicotine in the toenails, the higher the risk of coronary heart disease.
New analysis of a drug approved for osteoporosis prevention and treatment has provided definitive evidence that the medication is also effective as a breast cancer preventative for certain cancers. Women who took the drug raloxifene were less likely to develop invasive, estrogen-receptor (ER) positive breast cancer compared with women who did not take the drug.
Sun exposure and vitamin D levels may play a strong role in risk of type 1 diabetes in children, according to new findings by researchers at the Moores Cancer Center at University of California, San Diego and the Department of Family and Preventive Medicine. This association comes on the heels of similar research findings by this same group regarding vitamin D levels and several major cancers.
New research from the University of California, San Diego Department of Medicine, Division of Nephrology, shows that the anti-rejection drug sirolimus (brand name Rapamune) may help prolong the clinical benefit of transplanted kidneys and delay rejection, especially in patients who do not regularly take their prescribed medications (are "non-compliant").
Through an advanced minimally-invasive procedure called laparoscopy, Andrew M. Lowy, M.D., chief of surgical oncology at Moores UCSD Cancer Center, has completely removed a cancerous tumor without the need for a large 8-12 inch incision.
Every year more than 100,000 U.S. patients undergo gastric bypass surgery for the treatment of obesity. 20 percent of these patients will regain weight within a few years after the surgery and will be at renewed risk for diseases. The Center for the Treatment of Obesity at UC San Diego Medical Center now offers a new incision-free procedure to reverse weight gain after gastric bypass surgery.
Researchers at UC San Diego School of Medicine are challenging conventional thinking with a study showing that modest wine consumption, defined as one glass a day, may not only be safe for the liver, but may actually decrease the prevalence of Non-Alcoholic Fatty Liver Disease (NAFLD).
"Every week, someone arrives at UC San Diego Medical Center facing significant life changes because of a split-second accident," said Abrams. "My role as a surgeon is to offer treatment options that deliver satisfying lifelong solutions. You decide what's viable and remove what's not. A finger that is painful, stiff, or with no feeling, may not be worth keeping."
Victor Nizet, M.D., a professor of pediatrics and pharmacy at the University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences, and physician at the Rady Children's Hospital San Diego, has been selected as the 2008 recipient of the most prestigious award in pediatric research by the Pediatric Academic Societies.
Stuart Jamieson, M.D., F.R.C.S, Distinguished Professor of Surgery, Chief, Division of Cardiothoracic Surgery, and Director of the Lung Transplant Program at the UC San Diego Medical Center will receive the Ellis Island Medal of Honor May 10, 2008 in the Great Hall on Ellis Island.
Division of Hospital Medicine at the UCSD Medical Center has received national recognition for a program that protects hospital patients from developing those blood clots. The medical center's Venous Thromboembolism Prevention Team was awarded the Society of Hospital Medicine's first ever Team Approaches in Quality Improvement Award at the Hospital Medicine 2008 meeting in San Diego in April.
A $2.5 million basic research core grant to establish a Digestive Diseases Research Development Center (DDRDC) has been awarded to UC San Diego's Division of Gastroenterology. The grant, funded by The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH), is the first-ever NIH Center award for the division.
Mark A. Talamini, M.D., professor and chairman of the department of surgery at UC San Diego Medical Center has assumed the role of president of The Society of American Gastrointestinal and Endoscopic Surgeons, the largest professional organization of gastrointestinal surgeons in the United States and the leading international society for modern minimally invasive and endoscopic surgery.
A strain of tuberculosis called Mycobacterium bovis, associated more often with cattle than humans, is increasing in San Diego and is concentrated mostly in Hispanics of Mexican origin, according to a study conducted by researchers at the UCSD School of Medicine in collaboration with San Diego County public health officials.
More than 30 years ago, Kenneth Lyons Jones, M.D., pediatrician and pioneering specialist in the study of birth defects, helped identify what is now commonly known as fetal alcohol syndrome (FAS). Now, Jones has received a grant from The Hartwell Foundation to examine another possible link: poor diet, pregnancy, and birth defects.
Across the United States, parents are invited to take their sons and daughters to work on April 24. In a hospital environment where patient privacy and safety are paramount, bringing loved ones to work isn't always possible, especially for an employee of an operating room. The staff at UC San Diego Medical Center devised a heartfelt solution.
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