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Johns Hopkins Medicine researchers report that a prospective study of 14 infants and children demonstrated that convalescent plasma — a blood product collected from patients recovered from infections with the coronavirus (SARS-CoV-2) that causes COVID-19— was safe in high risk children infected with or exposed to the virus.
A Johns Hopkins Medicine scientist who spent 30 years figuring out how to put chemical labels into cells to track their movement in living tissues has found that certain self-renewing stem cells have built-in tracers — made out of sugars — that can do the job without added chemical “labels” when injected into mouse brains.
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Amita Gupta, M.D., M.H.S., an expert in the global treatment, prevention and control of diseases such as acquired immunodeficiency syndrome (AIDS) and tuberculosis (TB), has been named as the seventh director of Johns Hopkins Medicine’s Division of Infectious Diseases.
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Johns Hopkins Medicine has announced that plastic and reconstructive surgeon Fan Liang, M.D., will become the next medical director of the Johns Hopkins Center for Transgender Health (CTH), one of the premier institutions of its kind in the nation.
A genome study undertaken by Johns Hopkins Kimmel Cancer Center researchers to look for variants in a gene considered a fundamental building block for microscopic structures that synthesize proteins took a surprising twist.
Haig Kazazian Jr., M.D., a pioneering scientist in the field of genetic medicine, died Jan. 19 of congestive heart failure. He was 84 and a resident of Baltimore.
Three Johns Hopkins University School of Medicine researchers have been elected by their peers as fellows of the American Association for the Advancement of Science (AAAS), an international nonprofit organization dedicated to advancing science, and the publisher of the Science family of journals.
For research to be applicable to all segments of the population, Swenor and her co-author, Jennifer Deal, Ph.D., M.H.S., assistant professor of epidemiology at the Johns Hopkins Bloomberg School of Public Health, say that guidelines for including people in specific studies should avoid ruling out people with disabilities.
In a study published Jan. 24 in The Lancet Regional Health – Americas, Scott Pilla, M.D., M.H.S., an assistant professor of medicine at the Johns Hopkins University School of Medicine, Ahmed Elhussein, M.P.H, Jeanne Clark, M.D., M.P.H and their colleagues conducted a study to determine how often patients of different racial or ethnic groups started newer diabetes medications.
About a fifth of young sexual minority males and transgender females are estimated to be engaging in transactional, or survival sex, according to results of a new survey study by Johns Hopkins Medicine researchers.
New pose estimation software has the potential to help neurologists and their patients capture important clinical data using simple tools such as smartphones and tablets, according to a study by Johns Hopkins Medicine...
Thousands of schools transitioned to online learning in 2020 due to the COVID-19 pandemic, during which time many children with cancer and other chronic health needs, as well as those with special education needs, faced significant challenges to learning online. An opinion paper by Johns Hopkins experts, published Jan. 4 in the journal JAMA Pediatrics, highlights some of the issues faced by families and offers suggestions to move forward.
Remdesivir, an antiviral drug used to treat COVID-19, increased the likelihood of clinical improvement in COVID-19 patients on low-flow oxygen or no oxygen, according to a new study authored by the Johns Hopkins University School of Medicine, the Johns Hopkins Bloomberg School of Public Health.
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Researchers from Johns Hopkins Medicine report that a rapid antigen test for SARS-CoV2 proved highly accurate in a study with patients aged 17 and younger.
A new analysis of national kidney transplant and organ discard data concludes that too many deceased donor organs with acute kidney injury (AKI) may be needlessly going to waste because of a change in the way kidneys are evaluated.
A patient believed to have suffered a stroke typically gets transported to the nearest emergency room for tests to determine the best course of action. Telemedicine at Johns Hopkins Medicine enabled one patient to have her stroke diagnosed and a treatment plan set up without ever stepping foot in a hospital.
The new year brings resolutions, and at the top of many lists are dieting and exercising. But, buying a treadmill to reach your goal comes with risks. It’s something 3-year-old Hazel Beckman’s family knows far too well.
Johns Hopkins Medicine researchers have developed a color-coded test that quickly signals whether newly developed nanoparticles — ultra small compartments designed to ferry medicines, vaccines and other therapies — deliver their cargo into target cells. The new testing tool, engineered specifically to test nanoparticles, could advance the search for next-generation biological medicines.
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A novel analysis of medical records for a racially diverse group of more than 6,000 women has added to evidence that some combination of biological, social and cultural factors — and not race alone — is likely responsible for higher rates of preeclampsia among Black women born in the United States compared with Black women who immigrated to the country.
South African geneticist Ambroise Wonkam, M.D., Ph.D., D.Med.Sc., has been selected as Johns Hopkins Medicine’s director of the Department of Genetic Medicine and the McKusick-Nathans Institute of Genetic Medicine.
The results of a nationwide, multicenter clinical trial led by Johns Hopkins Medicine and the Johns Hopkins Bloomberg School of Public Health provides solid evidence for the use of plasma from convalescent patients — those who have recovered from the disease and whose blood contains antibodies against SARS-CoV-2, the virus that causes COVID-19 — as an early treatment
To solve the mysteries of how learning and memory occur, Johns Hopkins Medicine scientists have created a system to track millions of connections among brain cells in mice — all at the same time — when the animals’ whiskers are tweaked, an indicator for learning.
Treating bacterial infections associated with orthopaedic implants has often been a case of too little, too late. The traditional therapy has been a combination of prolonged antibiotics, including rifampin, a 50-year-old drug that has been a staple in the global fight against tuberculosis and other bacterial diseases.
Johns Hopkins astrophysicist, Alexander Szalay, Ph.D., and Kimmel Cancer Center pathologist Janis Taube, M.D., M.Sc., received a Life Sciences 2021 award for AstroPath at this year’s Falling Walls Science Summit, an international event honoring research breakthroughs from across the globe.
REsearchers at Johns Hopkins Medicine, the University of Maryland Medical Center, the University of Maryland School of Medicine and four other collaborators report that a rapid antigen detection test for SARS-CoV-2, the virus that causes COVID-19, proved more effective than expected when compared with virus detection rates using the established standard test, the polymerase chain reaction (PCR) assay.
Human heart muscle cells cease to multiply after birth, making any heart injury later in life a permanent one, reducing function and leading to heart failure. Now, however, Johns Hopkins Medicine researchers say they have new evidence from mouse experiments that manipulating certain nerve cells or the genes that control them might trigger the formation of new heart muscle cells and restore heart function after heart attacks and other cardiac disorders.
Ever since the first barcode appeared on a pack of chewing gum in 1974, the now-ubiquitous system has enabled manufacturers, retailers and consumers to quickly and effectively identify, characterize, locate and track products and materials. In a paper first posted online Nov. 26, 2021, in the journal Cell, researchers at Johns Hopkins Medicine and The Johns Hopkins University demonstrate how they can do the same thing at the molecular level, studying the ways cancer cells “talk” with one another.
Johns Hopkins Medicine researchers report they have genetically mapped the cell types that make up the mouse iris — the thin disc of pigmented tissue that, in humans, gives eyes their distinct colors.
Clonal hematopoiesis, a condition in which mutations associated with blood cancers are found in the blood of healthy people, is common with aging. When looking for appropriate stem cell/bone marrow donors, clinicians tend to stay away from older donors with clonal hematopoiesis (CH) because of concerns about passing potentially premalignant stem cells to the recipient.
Johns Hopkins Medicine scientists have used glowing chemicals and other techniques to create a 3D map of the blood vessels and self-renewing “stem” cells that line and penetrate a mouse skull. The map provides precise locations of blood vessels and stem cells that scientists could eventually use to repair wounds and generate new bone and tissue in the skull.
An international study of more than 400 adults concludes that people who undergo mitral valve surgery (between the left atrium and the left ventricle of the heart) and also have less than severe leakage of the tricuspid valve (a section of the heart that directs blood from the right atrium to the ventricle) may benefit from having both valves repaired at the same time.
A recent study by Johns Hopkins Medicine researchers provides evidence that CD4+ T lymphocytes produced by people who received either of the two available messenger RNA (mRNA) vaccines for COVID-19 persist six months after vaccination at only slightly reduced levels from two weeks after vaccination.
A new study using genetically engineered mice and human cell and tissue samples has added to evidence that higher levels of inflammatory chemicals involved in fat metabolism occur in people with amyotrophic lateral sclerosis (ALS), the neuromuscular disorder, also known as Lou Gehrig’s disease.
Hopkins Medicine researchers say they have found that a protein that helps form a structural network under the surface of the cell’s “command center” — its nucleus — is key to ensuring that DNA inside it remains orderly.
For the second straight year, flu season is emerging against the backdrop of the COVID-19 pandemic. While the number of flu cases was relatively low last year, experts at Johns Hopkins Medicine say that this year, it could be much higher.
Johns Hopkins has received a $20 million grant from the National Institute on Aging that will spur the development of artificial intelligence devices (AI) to improve the health of older adults and help them live independently for longer — a relatively untapped use of this technology.
As the COVID-19 pandemic continues, many children have returned to school in-person this year for the first time in 18 months. The instruction may be the same, but the classrooms look and feel much different with safety measures in place to help prevent spread of the virus. These precautions range from masking to keeping children with runny noses and coughs home from school.
Leptin, a molecule produced by fat cells, appears to cancel out the effects of the estrogen-blocking therapy tamoxifen, a drug commonly used to treat and prevent breast cancers, suggests a new study led by researchers from the Johns Hopkins Kimmel Cancer Center.
Johns Hopkins researchers identified two distinct clusters of patients with PN: those who had increased inflammation in the blood, and those who did not but were more likely to have a history of spinal disease, which may sensitize the nerves. Identifying those with unique types of inflammation may help doctors provide more precise and personalized treatment for the disorder.
Combining the immunotherapy agent durvalumab with the chemotherapy agents pemetrexed and cisplatin or carboplatin may provide a new treatment option for patients who have inoperable pleural mesothelioma, a cancer of the tissues lining the lungs, according to a phase II clinical trial led by researchers at the Johns Hopkins Kimmel Cancer Center and the Bloomberg~Kimmel Institute for Cancer Immunotherapy.
Johns Hopkins Medicine (JHM) has been designated a National Organization for Rare Disorders (NORD) Rare Disease Center of Excellence. The newly established designation recognizes centers who are leaders in the diagnosis and care of people with rare diseases. JHM shares the recognition with the Kennedy Krieger Institute.
Researchers at Johns Hopkins Medicine and Italy’s Catholic University of the Sacred Heart medical school have provided solid evidence that copper, the first metal used medicinally, may now have a new role — helping save children from a devastating central nervous system cancer known as medulloblastoma.
The immune checkpoint protein B7-H3 may be a promising new target for immunotherapy in treatment-resistant prostate cancers, according to two new studies led by researchers at the Johns Hopkins Kimmel Cancer Center. The studies were presented recently at the European Society for Medical Oncology (ESMO) 2021 Conference.
A new analysis led by Johns Hopkins Medicine researchers finds that the number of U.S. adults who report they have a disability is 27%, representing 67 million adults, an increase of 1% since the data were last analyzed in 2016. In this new study, which used data collected in 2019, before the COVID-19 pandemic, the researchers found a wide array of disparities between socioeconomic and demographic factors that persists among those who identify as disabled and those who do not.
In what is believed to be one of the largest studies of its kind, Johns Hopkins Medicine researchers have shown that antibody levels against SARS-CoV-2 (the COVID-19 virus) stay more durable — that is, remain higher over an extended period of time — in people who were infected by the virus and then received protection from two doses of messenger RNA (mRNA) vaccine compared with those who only got immunized.
Johns Hopkins Medicine is one of three research institutions with scientists awarded $8.9 million to study the growing body of evidence that Parkinson’s disease originates among cells in the gut and travels up the body’s neurons to the brain. The research aims to develop treatments to prevent or halt progression of the disease.
Findings from a recent Johns Hopkins Medicine-led study of nearly 4,500 patients hospitalized with COVID-19 over a four-month period provide a stronger case for a very different conclusion: Statins likely did not confer any impact — positive or negative — on COVID-related mortality and may be associated with an significantly increased risk — nearly 1 chance in 5 — of more serious illness.
As more people travel into space, Johns Hopkins Medicine experts expect more physicians will see patients with space travel-related pain.
Ten faculty members of The Johns Hopkins University and Johns Hopkins Medicine have been elected to the National Academy of Medicine, an independent organization of leading professionals from diverse fields, including health, medicine and the natural, social and behavioral sciences. It serves alongside the National Academy of Sciences and the National Academy of Engineering as adviser for the nation and the international community.
Johns Hopkins Medicine was awarded a grant from the National Institutes of Health (NIH) to explore the potential impacts of psilocybin on tobacco addiction.
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