A study led by UNC Lineberger Comprehensive Cancer Center researchers found that preference for preserving sexual function was not strongly reflected in the treatment choices of men with low-risk prostate cancer.
UNC researchers use their new research platform to discover new cell subpopulations and crucial cellular players in the process of turning damaged heart tissue back into healthy heart muscle. The research platform could be used to study other biological processes and create tailored therapies.
In a new study published in Cell Systems, UNC Lineberger's Jeremy Purvis, PhD, and colleagues report that the timing of when DNA damage occurs within these different checkpoints matters to a cell’s fate.
UNC-Chapel Hill and UC-San Francisco scientists solved the crystal structure of a specific dopamine receptor called D4 at an incredibly high resolution and designed a new compound that tightly binds only to D4 and none of the other 320 receptors they tested.
Using laboratory equipment readily available in developing countries, researchers from UNC and Abbott Diagnostics were able to define and map the burden of hepatitis C virus for the first time in the Democratic Republic of the Congo. Their findings were published in Clinical Infectious Diseases.
The book, titled “Drinking, Drug Use and Addiction in the Autism Community,” explores why addiction is more common among individuals with ASD than it is within the general population and investigates how addiction and autism affect one another.
The UNC Center for Health Innovation is included in a new list of 58 Hospitals and Health Systems with Innovation Programs, published today by Becker’s Hospital Review.
During head injury, a common problem is damage to axons – long stalks that grow out of the bodies of neurons. After a strong jolt to the head, axons can break or swiftly degenerate. UNC’s Anne Taylor and colleagues have revealed new molecular details of this and a path toward repairing axons.
UNC-Chapel Hill has a new study in JAMA that challenges long-held practices of testing AMH and FSH levels to predict reproductive potential.
Researchers report in JAMA Dermatology that surgical treatment delays – defined as surgery that occurred more than six weeks after diagnosis – were common. Medicaid patients were 36 percent more likely than private insurance patients to experience delays.
Preliminary findings presented at this year’s American Society for Radiation Oncology Annual Meeting suggest a genetic test for HPV16 in the blood could be useful to help assess risk for patients, and could help identify patients suitable for lower treatment doses.
UNC School of Medicine cardiologist Anil Gehi, MD, will use a $1.7 million grant from the Bristol-Myers Squibb Foundation to further innovate a care model, launched in 2015, that reduced hospitalizations for patients with atrial fibrillation (Afib) presenting in the emergency room by more than 30 percentage points in its first year.
Scientists at the UNC School of Medicine and elsewhere are exploring ways to reprogram scar tissue cells into healthy heart muscle cells, and now UNC researchers have published the first scientific paper to compare in great detail the two leading reprogramming techniques.
Eva Anton’s lab at UNC has shown how the deletion of the protein APC in progenitor cells – which give rise to neurons – disrupts the Wnt protein pathway, which previously was linked to genes associated with autism.
In a study published in PLOS ONE, UNC School of Medicine researchers found that skills developed during science PhD programs translate to success in a wide range of fields.
The calculator estimates the impact of differences in breastfeeding rates, providing policy makers and advocates with ways to approximate return on investment for measures that help enable breastfeeding.
Cost savings fell below expectations for generic versions of an orally administered cancer treatment in an analysis by University of North Carolina Lineberger Comprehensive Cancer Center researchers. The findings raise questions about the extent to which generic drugs can help control care costs for cancer treatments.
Mucin levels – the proteins that make mucus thick – is abnormally high in chronic bronchitis and mucin concentrations are associated with disease severity. This finding could become the first-ever objective marker of chronic bronchitis and lead to the creation of diagnostic and prognostic tools.
Scientists have known that abnormal protein deposits and swarms of activated immune cells accumulate in brains of people with Alzheimer’s. Now researchers have untangled how these proteins and inflammation interact in lab experiments to reveal how therapies might reverse the disease process.
Working at a health center in rural Uganda, researchers from the University of North Carolina at Chapel Hill demonstrated for the first time the potential of using a low-cost, routinely available rapid diagnostic test to distinguish between severe and uncomplicated malaria in children.
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