An international research team has developed a meta-scale approach to quantifying the human proteome and the massive number of protein variants produced by the human body. Proteomics is a cornerstone of biology and a precursor to understanding how protein dysfunction contributes to disease.
The public is invited to help determine the winners of the 2023 Ethics Cartooning Competition, an annual contest that encourages scientists to shed light on timely or recurring issues that arise in scientific research.
Wisconsin virologists have outlined in atomic detail the intricate RNA replication machines that coronaviruses create inside infected cells, giving rise to potential new strategies to fight disease.
For the first time, researchers have assembled a high-quality reference genome for the Nile rat, a promising model organism for diabetes research.
An advanced biomedical imaging techniques reveals how cancer cells can hijack the metabolic activity of certain non-cancer cells in the pancreas to fuel tumor growth.
The Morgridge Institute for Research will broadcast a free webinar on November 9, featuring a conversation with experts on the front lines of pediatric vaccine development and public health.
Morgridge researchers developed an imaging technique that can predict the efficiency of cardiac muscle cell differentiation from stem cells as a method of quality control for potential regenerative therapies.
The National Institutes of Health (NIH) is embarking on a massive research project to shed light on early child development, including the health and developmental implications of opioid use during pregnancy. The very first task is to ensure the study — the HEALthy Brain and Child Development study (HBCD) — is on solid legal and ethical ground.
Portable Flamingo microscopes have the potential to democratize science by opening up new opportunities to wide ranges of researchers and institutions.
Five prizes were awarded in the fourth annual Morgridge Institute for Research Ethics Cartooning Competition, addressing the social impacts of scientific research, like issues on public health and communication during the COVID-19 pandemic.
The Morgridge Institute for Research launched the fourth annual Ethics Cartooning Competition, and public voting is now open to select the winners out of 17 semi-finalists.
A Morgridge imaging study of macrophages — immune cells that are important to human health, but paradoxically can help some cancers grow and spread — is offering better ways to understand these cells and target them with immunotherapies.
Researchers from the Morgridge Institute for Research, the University of Wisconsin-Madison, and Albany Medical College have identified more than 200 molecular features that strongly correlate with COVID-19 severity, offering insight into potential treatment options for those with advanced disease.
A national research initiative announced today will place the University of Wisconsin-Madison at the forefront of a revolution in imaging fostered by cryo-electron microscopy and cryo-electron tomography - technologies that can illuminate life at the atomic scale.
A team of developmental biologists at the Morgridge Institute for Research has discovered a means by which schistosomes, parasitic worms that infect more than 200 million people in tropical climates, are able to outfox the host’s immune system.
A new imaging method developed by the Skala lab uses the natural autofluorescence within cells to assess T cell activity. The technique could help assess T cell involvement in immunotherapies.
For the first time, scientists at the Morgridge Institute for Research have generated near atomic resolution images of a major viral protein complex responsible for replicating the RNA genome of a member of the positive-strand RNA viruses.
The Rural Summer Science Camp typically invites participants from rural school districts across Wisconsin to a weeklong camp at the Morgridge Institute for Research. Due to the coronavirus pandemic, the Rural Summer Science Camp is celebrating a new milestone: an entirely digital experience.
The Morgridge Institute for Research will broadcast a free webinar on Tuesday, June 2 to offer insight on the basic science behind the COVID-19 pandemic, the state of virology research at Morgridge, and how that research will provide new ways to combat emerging viral threats.
Even after heroic medical and societal efforts finally break the back of the current COVID-19 pandemic, the global sigh of relief may not last long. The chilling reality is that viral threats are growing more common. And they’re getting deadlier.
A physician on the COVID-19 front lines—Dr. Ariel Jaitovich, a pulmonary and critical care physician at the Albany Medical Center in New York—sought out a collaboration with investigators at the Morgridge Institute for Research and the Department of Biomolecular Chemistry at the University of Wisconsin School of Medicine and Public Health (SMPH) to better understand the molecular profile of COVID-19 and provide insights that may improve treatment.
Schistosomiasis is one of the most devastating tropical diseases in the world, second only to malaria in its prevalence. The only treatment currently used is extremely limited in its effectiveness and in who it can help. The Newmark Lab wants to develop something that protects people from being infected in the first place.
Wearable, smart technologies are transforming the ability to monitor and improve health, but a decidedly low-tech commodity — the humble toilet — may have potential to outperform them all.
The recent development of physiologic cell culture media, which models in vivo conditions, holds immense potential to improve understanding of human biology.
A team at the Morgridge Institute for Research has characterized a natural chemical that paralyzes the parasite that causes schistosomiasis, offering a new pathway to fight the catastrophic neglected disease.
Pediatric anesthesia is a stressful and critical environment. Dr. Bilen-Rosas wants to help clinicians recognize dangerous sedation pathologies sooner. She teamed up with the Morgridge Fab Lab to create a new medical device that alerts clinicians to compromised airways.
Scientists show that the location of stem cells is essential in determining tapeworms’ ability to regenerate.
In the game against an essentially unlimited pool of virus threats, humanity is seriously outmatched. In order to shift the balance, scientists need to change the game.
Scientists at the Morgridge Institute for Research have created a new way to study early human developmental timing through a stem cell-based “clock in a dish."
Preterm birth is a global health problem without a solution. Dr. Helen Feltovich wants to develop non-invasive, safe imaging tools to better identify the risk of preterm birth. She teamed up with Melissa Skala’s Lab at the Morgridge Institute to take a closer look at placental membranes during pregnancy and delivery.
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