UC San Diego and its collaborating partners have been awarded $10 million from the Howard Hughes Medical Institute to leverage the biomedical promise of viruses known as bacteriophages as new therapeutic agents in the fight against the rising crisis of antibiotic-resistant bacterial infections.
For the first time, researchers at UC San Diego have created an atomic-level computer model of the H1N1 virus that reveals new vulnerabilities, suggesting possible strategies for the design of future vaccines and antivirals against influenza.
Engineers and physicians have developed a wearable ultrasound device that can assess both the structure and function of the human heart. The portable device, which is roughly the size of a postage stamp, can be worn for up to 24 hours and works even during strenuous exercise.
UC San Diego Herbert Wertheim School of Public Health and Human Longevity Science study: senior women were less likely to develop mild cognitive impairment or dementia if they did more daily walking and moderate-to-vigorous physical activity.
Researchers at University of California San Diego and UC Riverside have further elucidated the molecular pathway used by the SARS-CoV-2 virus to infect human lung cells, identifying a key host-cell player that may prove a new and enduring therapeutic target for treating COVID-19.
UC San Diego researchers describe how pancreatic cancer stem cells leverage a protein in a family of proteins that normally suppress tumors to instead do the opposite, boosting their resistance to conventional treatments and spurring growth.
Five years after the deadliest and most destructive wildfire in California history, UC San Diego researchers document persistent differences in cognitive function among survivors.
Researchers have developed a new system for developing gene drives for areas ranging from human health to global food supplies. The new “hacking” system converts split gene drives into full drives, offering new flexibility for safely conducting gene drive experiments in a range of applications.
UC San Diego researchers identify mutation that causes excessive folding in human brain’s wrinkly cerebral cortex, resulting in diminished cognitive function.
Publicly available salary information prompts organizations to reduce the gender pay gap, according to a new study from the University of California San Diego’s School of Global Policy and Strategy.
UC San Diego scientists discover a molecular pathway critical to the initiation of pancreatic tumors. The findings may inspire new chemotherapeutic drugs targeting early stages of tumor formation and spread.
Human cells are often a mixture of both abnormal and normal DNA – a mosaic, so to speak, and like the art form, this complex montage is difficult to understand. Neuroscience researchers are training computers to unveil new methods for DNA mosaic recognition.
An international consortium led by UC San Diego has identified at least some of the genetic drivers of a mysterious form of pediatric epilepsy.
From volunteering in a beach cleanup to learning new ways to promote equity, the start of a new year is the perfect time to take steps to help spark positive change. During UC San Diego’s Changemaker Kickoff Week, campus community members can jump into opportunities to continue building the knowledge and skills needed to make the world a better place for all.
UC San Diego researchers suggest that rising levels of manmade chemicals, accumulating in marine plankton, might be used to monitor the impact of human activity on ecosystem health and perhaps study links between ocean pollution and land-based rates of childhood and adult chronic illnesses.
UC San Diego researchers describe a method for teaching a computer how to spot complex “mosaic mutations” using an artificial intelligence approach termed “deep learning.”
UC San Diego study reveals critical insights into the complex biology of tissue-specific T cells, paving the way for a new branch of precision therapeutics in immunity, autoimmunity, and cancer.
For the first time, researchers at UC San Diego have shown that changes in gene expression happen almost entirely during the transcription stage while the cells are growing. The researchers have provided a simple quantitative formula linking regulatory control to mRNA and protein levels.
Researchers at UC San Diego provide new insights into the pathology of limbic predominate age-related TDP-43 encephalopathy, which mimics Alzheimer’s, making it very difficult to identify in living patients.
UC San Diego Herbert Wertheim School of Public Health and Human Longevity Science led 70 participants from 14 nations in a discussion on the ways in which a gene drive project registry could both contribute to and detract from the fair development, testing and use of gene-drive modified organisms.
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