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Women with metastatic breast cancer to the bone may be able to receive bisphosphonates, the bone-targeting class of drugs like zoledronic acid, less often after the first year of monthly administration. With that practice change, women may also reduce their risk of serious side effects, according to a study led by researchers at The University of Texas MD Anderson Cancer Center.

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Researchers at The University of Texas MD Anderson Cancer Center and other institutions have applied a newly developed software tool to identify genetic mutations that contribute to a person’s increased risk for developing common, complex diseases, such as cancer.

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Dr. Condoleezza Rice was the honoree of The University of Texas MD Anderson Cancer Center’s A Conversation With a Living Legend®, Wednesday, May 21 at the Westin Galleria. Significantly surpassing all past years’ fundraising totals for the Houston event, it attracted 930 guests and raised more than $1,031,000 for MD Anderson’s Moon Shots Program, an unprecedented, comprehensive effort to significantly reduce cancer deaths and to transform cancer care, initially focusing on eight cancers. Proceeds will be used specifically to support the Prostate Cancer Moon Shot.

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Oncologists now have a new understanding of the toxicity levels of specific chemotherapy regimens used for women with early stage breast cancer, according to research from The University of Texas MD Anderson Cancer Center.

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In a small study, researchers from The University of Texas MD Anderson Cancer Center found that 93 percent of head and neck cancer patients treated with multi-field optimization intensity modulated proton therapy (MFO-IMPT) were cancer-free 28 months after treatment.

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Myeloid-derived suppressor cells (MDSCs), are found abundantly in the microenvironment around tumors. They interfere with immune response, promoting cancer progression. MD Anderson researchers have found a potential route to target MDSCs

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Fibrous tissue long suspected of making pancreatic cancer worse actually supports an immune attack that slows tumor progression but cannot overcome it, scientists at The University of Texas MD Anderson Cancer Center report in the journal Cancer Cell.

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In an effort to combat lung cancer and other serious diseases, The University of Texas MD Anderson Cancer Center will adopt a tobacco-free hiring policy beginning, Jan. 1, 2015.

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The University of Texas MD Anderson Cancer Center this week honored 16 junior faculty members who are expected to become some of America's future cancer leaders. The faculty members are the first R. Lee Clark Fellow award winners. The new award was established to recognize outstanding work by junior faculty members and to help support their future efforts.

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A tumor-suppressing protein acts as a dimmer switch to dial down gene expression. It does this by reading a chemical message attached to another protein that’s tightly intertwined with DNA, a team led by scientists at The University of Texas MD Anderson Cancer Center reported at the AACR Annual Meeting 2014.

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Agreement finalizes institution’s program with large pharmaceutical companies

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Comprehensive genomic analysis of low-grade brain tumors sorts them into three categories, one of which has the molecular hallmarks and shortened survival of glioblastoma multiforme

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Inhibiting cancer-promoting prolactin causes unconventional cell death in preclinical research

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Elite recognition for life-saving innovations of drug combinations, immunotherapy for cancer.

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MD Anderson’s Allison honored; “Many cancer patients are alive today because of his vision”

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Two champions of gender equality in medicine and research will be honored by The University of Texas MD Anderson Cancer Center at 4 p.m., today in MD Anderson’s Onstead Auditorium.

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MD Anderson Cancer Center and MedImmune, the global biologics research and development arm of AstraZeneca, will collaborate to develop therapies that unleash patients’ immune systems to attack their cancers.

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Computed tomography (CT) scans routinely taken to guide the treatment of pancreatic cancer may provide an important secondary benefit. According to new research from The University of Texas MD Anderson Cancer Center, the scans also reflect how well chemotherapy will penetrate the tumor, predicting the effectiveness of treatment.

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Airways near lung tumors provide clues to genetics of cancer

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For women with breast cancer undergoing radiation therapy, yoga offers unique benefits beyond fighting fatigue, according to research from The University of Texas MD Anderson Cancer Center.

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Research at The University of Texas MD Anderson Cancer Center is finally unearthing some of the ancient mysteries behind leprosy, also known as Hansen’s disease, which has plagued mankind throughout history. The new research findings appear in the current edition of journal PLOS Neglected Tropical Diseases. According to this new hypothesis, the disease might be the oldest human-specific infection, with roots that likely stem back millions of years.

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The angiogenesis inhibitor bevacizumab (Avastin) failed to increase overall survival (OS) or statistically significant progression-free survival (PFS) for glioblastoma patients in the frontline setting, according to a study led by researchers at The University of Texas MD Anderson Cancer Center.

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Discovering key elements of immune system T cell biology and applying that knowledge to create a new way to treat cancer has earned Jim Allison, Ph.D., the 2014 Szent-Györgyi Prize for Progress in Cancer Research from the National Foundation for Cancer Research.

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Quality leaders outline action plan for national oversight, collaboration and patient-centered approaches

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Today, CVS Caremark, the company that operates 7,600 CVS stores nationwide, announced the bold decision to stop selling tobacco products before the end of the year. The University of Texas MD Anderson Cancer Center applauds this decision. MD Anderson President Ron DePinho, M.D., today released the following statement.

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When comparing treatments designed to enable long-term breast preservation for older women with invasive breast cancer, researchers found those treated with brachytherapy were at higher risk for a later mastectomy, compared to women treated with standard radiation therapy.

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The once sketchy landscape of the molecular defects behind bladder cancer now resembles a road map to new, targeted treatments thanks to the unified efforts of scientists and physicians at 40 institutions.

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Two proteins compete for one binding site with metastasis at stake

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The University of Texas MD Anderson Cancer Center will collaborate with Johnson & Johnson Innovation, LLC, and its affiliate Janssen Biotech, Inc., to develop immunology-based cancer treatments through the MD Anderson Moon Shots Program immunotherapy platform.

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Fifty years ago this month, The U.S. Surgeon General jumpstarted America’s efforts to combat lung cancer and other diseases caused by smoking with the release of the 1964 U.S. Surgeon General’s Report on Smoking and Health.

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IMRT reduces side effects, also improves outcomes

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A simple blood test that can locate gene defects associated with cancer? New MD Anderson research suggests the technology may not be too far off

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Pfizer and MD Anderson sign first agreement to advance cancer immunotherapy through MD Anderson's Moon Shots Program immunotherapy platform

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Freeing the immune system to track down and kill tumors is helping a widening circle of patients.

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Basic science research that exposed vital details of cancer’s defense against the immune system, revealing an entirely new way to combat these diseases, has earned Jim Allison, Ph.D., a Breakthrough Prize in Life Sciences.

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Abstract #P3-06-02

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Drug combination reins in follicular lymphoma.

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PKM2 controls mitosis, saving cancer cells from death and promoting brain tumor growth

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A protector for PTEN, a tumor-thwarting protein often missing in cancer cells, has emerged from research led by scientists at The University of Texas MD Anderson Cancer Center published online at Nature Cell Biology this week.

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Andreeff, Do, Dmitrovsky and Wood honored for distinguished scientific efforts.

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Phase III trial examines pathological complete response rate

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Lung cancer is the number one cancer killer in the U.S., causing more deaths than the next three most common cancers – colon, breast and prostate – combined. Worldwide, lung cancer accounts for 1.3 million deaths annually. An estimated $10.3 billion per year is spent in the U.S. on lung cancer treatment alone, yet those diagnosed with the disease have just a 15 percent survival rate.

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James Allison wins @TheEconomist 2013 Innovation Award for bioscience.

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Tobacco misconceptions prevail in the United States despite the dramatic drop in smoking rates since the release of the first Surgeon General’s Report on smoking and health in January 1964. Experts at The University of Texas MD Anderson Cancer Center dispel common myths and share new educational resources to address this persistent challenge.

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Two leaders at The University of Texas MD Anderson Cancer Center have been elected to the Institute of Medicine (IOM) of the National Academies in recognition of their contributions to medical science and health care.

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Children of melanoma survivors were more likely to wear hats and re-apply sunscreen after receiving a multi-media informational program designed specifically for them. These new findings were included in research published in the journal of Cancer Epidemiology, Biomarkers and Prevention – a publication of the American Association for Cancer Research.

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NIH awards MD Anderson anti-asthma project.

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Commentary in Nature Genetics describes the new initiative and its potential implications for cancer research and future treatment.