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Released: 5-Mar-2020 3:35 PM EST
For the evaluation and treatment of diabetic eye disease, ultra-wide field imaging techniques cannot be used interchangeably
Joslin Diabetes Center

Diabetic retinopathy can be diagnosed and graded with the use of a newer scanning technology called ultra-wide field (UWF) imaging, a system that generates high-quality pictures showing most of the retina. Research from the Joslin Diabetes Center’s Beetham Eye Institute has now shown that one technique, UFW fluorescein angiography, detects over three times more microaneurysms than UWF color imaging

Released: 9-Jan-2020 2:25 PM EST
New Closed-Loop System Offers Promise as Novel Treatment for Post-Bariatric Hypoglycemia
Joslin Diabetes Center

Post-bariatric hypoglycemia is a profoundly life-altering condition for patients. Having unpredictable hypoglycemia that people can't detect is really an unsafe situation. Researchers at Joslin Diabetes Center and Harvard John A. Paulson School of Engineering and Applied Sciences have developed a closed-loop system that automatically provides patients with an appropriate, as-needed dose of liquid glucagon to treat this condition.

Released: 16-Oct-2019 8:05 PM EDT
Artificial pancreas system better controls blood glucose levels than current technology
Joslin Diabetes Center

A multi-center randomized clinical trial evaluating a new artificial pancreas system — which automatically monitors and regulates blood glucose levels — has found that the new system was more effective than existing treatments at controlling blood glucose levels in people with type 1 diabetes.The study showed that the system improved participants’ blood glucose control throughout the day and overnight.

Released: 3-Oct-2019 10:05 AM EDT
The diabetes pandemic and the promise of connected care
Joslin Diabetes Center

Digital diabetes management systems (“connected diabetes care”) have the potential to become part of a new diabetes care model, augmenting the traditional practice of diabetes care by providing continuous and on-demand assistance that aligns with the 24/7 demands of diabetes as a chronic disease.

Released: 1-Oct-2019 11:05 AM EDT
High-fructose + high-fat diet damages mitochondria in the liver increasing risk of fatty-liver disease and metabolic syndrome
Joslin Diabetes Center

BOSTON – (October 1, 2019) – Researchers at Joslin Diabetes Center have found that high levels of fructose in the diet inhibit the liver’s ability to properly metabolize fat. This effect is specific to fructose. Indeed, equally high levels of glucose in the diet actually improve the fat-burning function of the liver. This explains why high dietary fructose has more negative health impacts than glucose does, even though they have the same caloric content.

Released: 29-Jul-2019 11:05 AM EDT
Discovery enables clear identification of diseased beta cells in type 2 diabetes
Joslin Diabetes Center

BOSTON – (July 29, 2019) – Researchers at Joslin Diabetes Center, an affiliate of Harvard Medical School, have unlocked the key to clearly identifying diseased beta cells in type 2 diabetes. This discovery has both research and therapeutic implications.Studies of diabetes rely on the ability of researchers to sort diseased cells from healthy cells.

Released: 10-Jul-2019 3:05 PM EDT
Ann Lagasse Elected to Chair of Board of Trustees
Joslin Diabetes Center

Ann Lagasse, principal at Ocean's Havens, LLC, of Newburyport, MA, has been elected to be the next chair of the Joslin Diabetes Center Board of Trustees.

   
Released: 10-Jul-2019 10:05 AM EDT
Martin Pasqualini Elected to Joslin Diabetes Center Board of Trustees
Joslin Diabetes Center

Martin Pasqualini, Managing Director of the CGA Group, has been elected to the Board of Trustees of Joslin Diabetes Center, an affiliate of Harvard Medical School.

   
Released: 10-Jul-2019 10:05 AM EDT
Susan Dacey Elected to Joslin Diabetes Center Board of Trustees
Joslin Diabetes Center

Susan Dacey, CEO and Chair of the Board of Directors for Industrial Polymers and Chemicals, Inc. has been elected to the Joslin Board of Trustees.

   
Released: 10-Jul-2019 10:05 AM EDT
Todd Abbrecht Elected to Joslin Diabetes Center Board of Trustees
Joslin Diabetes Center

Todd Abbrecht, Head of Private Equity at Thomas H. Lee Partners, has been elected to its Board of Trustees of the Joslin Diabetes Center, an affiliate of Harvard Medical School.

   
Released: 3-Jul-2019 4:25 PM EDT
Joslin Diabetes Center Remembers Lee Iacocca
Joslin Diabetes Center

Joslin Diabetes Center, an affiliate of Harvard Medical School, is paying tribute to the late Lee Iacocca, who passed away on July 2, at age 94. Mr. Iacocca was a generous supporter of research to find a cure for type 1 diabetes.

Released: 3-Jul-2019 4:15 PM EDT
Joslin Researchers Uncover Protective Factor in Diabetic Eye Disease
Joslin Diabetes Center

Researchers at Joslin Diabetes Center have shown that a protein found in the eye can protect against and potentially treat diabetic eye disease. At high enough levels, Retinol Binding Protein 3 (or RBP3) prevents the development of diabetic retinopathy. If introduced early enough in the development of the disease, RBP3 was shown to reverse the effects of the complication in rodent models of diabetes.

Released: 2-Jul-2019 4:05 PM EDT
Study suggests genetic testing for young people diagnosed with type 1 diabetes
Joslin Diabetes Center

BOSTON — (July 2, 2019) — A Joslin Diabetes Center study among people treated for type 1 diabetes for many years has discovered that a minority may have monogenic diabetes, a non-autoimmune inherited condition that in some cases does not require insulin treatment. “Our finding has clinical implications,” says George L. King, MD, Joslin Senior Vice President and Chief Scientific Officer, and senior author on a paper describing the work published in the Journal of Clinical Investigation.

Released: 28-Jun-2019 11:05 AM EDT
Chan-Zuckerberg Initiative taps Joslin researchers for Human Cell Atlas project
Joslin Diabetes Center

BOSTON – (June 28, 2019 – Researchers from Joslin Diabetes Center have been selected by the Chan-Zuckerberg Initiative (CZI) as one of 38 collaborative science teams that will launch CZI’s Seed Networks for a Human Cell Atlas projects.These collaborative groups will bring together scientists, computational biologists, software engineers, and physicians to support the continued development of the Human Cell Atlas (HCA), an international effort to map all cells in the human body.

Released: 25-Jun-2019 11:05 AM EDT
Performance-Enhancing Bacteria Found in the Microbiomes of Elite Athletes
Joslin Diabetes Center

BOSTON – (June 24, 2019) -- New research has identified a type of bacteria found in the microbiomes of elite athletes that contributes to improved capacity for exercise. These bacteria, members of the genus Veillonella, are not found in the guts of sedentary people. By taking a closer look at the bacteria, the researchers from Joslin Diabetes Center determined Veillonella metabolizes lactic acid produced by exercise and converts it into propionate, a short chain fatty acid.

Released: 11-Jun-2019 2:05 PM EDT
Genetic marker linked to increased risk of diabetic peripheral neuropathy
Joslin Diabetes Center

BOSTON – (June 11, 2019) – Researchers from Joslin Diabetes Center, using a genome-wide association study, have identified a genetic factor linked to the development of diabetic peripheral neuropathy. This finding suggests a new target for preventive therapies. The research has been published online and will appear in the August print issue of Diabetes.

Released: 4-Jun-2019 4:05 PM EDT
Researchers Restore Beta-Cell Function by Deleting Old Cells
Joslin Diabetes Center

Research from Joslin Diabetes Center has shown in mice that insulin resistance increases the proportion of aged beta-cells which are dysfunction. Such an increase in aged beta-cells could lead to type 2 diabetes. These researchers confirmed similarly increased proportion of aged beta-cells in islets recovered from humans with type2 diabetes.

Released: 20-May-2019 1:05 PM EDT
Study identifies enzymes that prevent diabetic kidney disease
Joslin Diabetes Center

BOSTON -- (May 13, 2019) -- A new study from Joslin Diabetes Center has proven that certain biological protective factors play a large role in preventing diabetic kidney disease in certain people. The study was published today in Diabetes Care. This study built on the findings from a 2017 Joslin Medalist Study of protective factors and diabetic kidney disease (or DKD).

Released: 6-May-2019 11:05 AM EDT
Pushing early beta-cell proliferation can halt autoimmune attack in type 1 diabetes model
Joslin Diabetes Center

Researchers at Joslin have found that increasing the proliferation and turnover of beta cells before signs of type 1 diabetes could halt the development of the disease.



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